 Antibody Affinity
"Antibody Affinity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
| Descriptor ID |
D000915
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| MeSH Number(s) |
G12.040 G12.122.125
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| Concept/Terms |
Antibody Affinity- Antibody Affinity
- Affinity, Antibody
- Affinities, Antibody
- Antibody Affinities
Antibody Avidity- Antibody Avidity
- Antibody Avidities
- Avidities, Antibody
- Avidity, Antibody
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Below are MeSH descriptors whose meaning is more general than "Antibody Affinity".
Below are MeSH descriptors whose meaning is more specific than "Antibody Affinity".
This graph shows the total number of publications written about "Antibody Affinity" by people in this website by year, and whether "Antibody Affinity" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 1 | 2 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 2 | 2 | | 2009 | 0 | 2 | 2 | | 2010 | 2 | 2 | 4 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 2 | 2 | | 2019 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antibody Affinity" by people in Profiles.
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Sprenger KG, Louveau JE, Murugan PM, Chakraborty AK. Optimizing immunization protocols to elicit broadly neutralizing antibodies. Proc Natl Acad Sci U S A. 2020 08 18; 117(33):20077-20087.
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Duan T, Tradtrantip L, Phuan PW, Bennett JL, Verkman AS. Affinity-matured 'aquaporumab' anti-aquaporin-4 antibody for therapy of seropositive neuromyelitis optica spectrum disorders. Neuropharmacology. 2020 01 01; 162:107827.
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Su Y, Liu Y, Behrens CR, Bidlingmaier S, Lee NK, Aggarwal R, Sherbenou DW, Burlingame AL, Hann BC, Simko JP, Premasekharan G, Paris PL, Shuman MA, Seo Y, Small EJ, Liu B. Targeting CD46 for both adenocarcinoma and neuroendocrine prostate cancer. JCI Insight. 2018 09 06; 3(17).
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Weisberg SP, Shaz BH, Tumer G, Silliman CC, Kelher MR, Cohn CS. PAS-C platelets contain less plasma protein, lower anti-A and anti-B titers, and decreased HLA antibody specificities compared to plasma platelets. Transfusion. 2018 04; 58(4):891-895.
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Eliaz I, Patil A, Navarro-Alvarez N, Wang Z, Eliaz A, Weil E, Wilk B, Sachs DH, Huang CA. Methods for the detection and serum depletion of porcine galectin-3. J Clin Apher. 2017 Oct; 32(5):335-341.
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Steck AK, Fouts A, Miao D, Zhao Z, Dong F, Sosenko J, Gottlieb P, Rewers MJ, Yu L. ECL-IAA and ECL-GADA Can Identify High-Risk Single Autoantibody-Positive Relatives in the TrialNet Pathway to Prevention Study. Diabetes Technol Ther. 2016 07; 18(7):410-4.
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Yu L, Laeyendecker O, Wendel SK, Liang F, Liu W, Wang X, Wang L, Pang X, Fang Z. Short Communication: Low False Recent Rate of Limiting-Antigen Avidity Assay Among Long-Term Infected Subjects from Guangxi, China. AIDS Res Hum Retroviruses. 2015 Dec; 31(12):1247-9.
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Bruderer U, van de Velde J, Frantzen I, De Bortoli F. Discrimination within epitope specific antibody populations against Classical swine fever virus is a new means of differentiating infection from vaccination. J Immunol Methods. 2015 May; 420:18-23.
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Gaensbauer JT, Rakhola JT, Onyango-Makumbi C, Mubiru M, Westcott JE, Krebs NF, Asturias EJ, Fowler MG, McFarland E, Janoff EN. Impaired haemophilus influenzae type b transplacental antibody transmission and declining antibody avidity through the first year of life represent potential vulnerabilities for HIV-exposed but -uninfected infants. Clin Vaccine Immunol. 2014 Dec; 21(12):1661-7.
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Fernández G, Manzardo C, Montoliu A, Campbell C, Fernández G, Casabona J, Miró JM, Matas L, Rivaya B, González V. Evaluation of an antibody avidity index method for detecting recent human immunodeficiency virus type 1 infection using an automated chemiluminescence immunoassay. Enferm Infecc Microbiol Clin. 2015 Apr; 33(4):238-42.
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