 Agrin
"Agrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein component of the synaptic basal lamina. It has been shown to induce clustering of acetylcholine receptors on the surface of muscle fibers and other synaptic molecules in both synapse regeneration and development.
| Descriptor ID |
D018171
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| MeSH Number(s) |
D12.776.631.050
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Agrin".
Below are MeSH descriptors whose meaning is more specific than "Agrin".
This graph shows the total number of publications written about "Agrin" by people in this website by year, and whether "Agrin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Agrin" by people in Profiles.
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Pawlikowski BT, Maimone MM. alpha-Dystrobrevin isoforms differ in their colocalization with and stabilization of agrin-induced acetylcholine receptor clusters. Neuroscience. 2008 Jun 23; 154(2):582-94.
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Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF. Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron. 2005 May 19; 46(4):569-79.
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Ferayorni AJ, Gunville CF, Grow WA. Nicotine decreases agrin signaling and acetylcholine receptor clustering in C2C12 myotube culture. J Neurobiol. 2004 Jul; 60(1):51-60.
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Cornish T, Chi J, Johnson S, Lu Y, Campanelli JT. Globular domains of agrin are functional units that collaborate to induce acetylcholine receptor clustering. J Cell Sci. 1999 Apr; 112 ( Pt 8):1213-23.
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