 GATA2 Transcription Factor
"GATA2 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential GATA transcription factor that is expressed primarily in HEMATOPOIETIC STEM CELLS.
| Descriptor ID |
D050989
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| MeSH Number(s) |
D12.776.260.235.625 D12.776.260.257.200 D12.776.930.216.625 D12.776.930.314.200
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| Concept/Terms |
GATA2 Transcription Factor- GATA2 Transcription Factor
- Transcription Factor, GATA2
- Transcription Factor GATA-2
- GATA-2, Transcription Factor
- Transcription Factor GATA 2
- NFE1B Erythroid Transcription Factor
- Nuclear Factor-Erythroid 1B
- Nuclear Factor Erythroid 1B
- GATA-Binding Protein 2
- GATA Binding Protein 2
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Below are MeSH descriptors whose meaning is more general than "GATA2 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GATA2 Transcription Factor".
This graph shows the total number of publications written about "GATA2 Transcription Factor" by people in this website by year, and whether "GATA2 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 2 | 0 | 2 | | 2017 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "GATA2 Transcription Factor" by people in Profiles.
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Wanet A, Bassal MA, Patel SB, Marchi F, Mariani SA, Ahmed N, Zhang H, Borchiellini M, Chen S, Zhang J, Di Ruscio A, Miyake K, Tsai M, Paranjape A, Park SY, Karasuyama H, Schroeder T, Dzierzak E, Galli SJ, Tenen DG, Welner RS. E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates. Sci Immunol. 2021 02 05; 6(56).
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Li Y, Gao J, Kamran M, Harmacek L, Danhorn T, Leach SM, O'Connor BP, Hagman JR, Huang H. GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers. Nat Commun. 2021 01 21; 12(1):494.
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Kamran M, Liang J, Liu B, Li Y, Gao J, Keating A, Mohamed F, Dai S, Reinhardt R, Jiong Y, Wu Z, Huang H. The Clusters of Transcription Factors NFATC2, STAT5, GATA2, AP1, RUNX1 and EGR2 Binding Sites at the Induced Il13 Enhancers Mediate Il13 Gene Transcription in Response to Antigenic Stimulation. J Immunol. 2020 12 15; 205(12):3311-3318.
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Hai L, Szwarc MM, He B, Lonard DM, Kommagani R, DeMayo FJ, Lydon JP. Uterine function in the mouse requires speckle-type poz protein. Biol Reprod. 2018 06 01; 98(6):856-869.
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Li Y, Liu B, Harmacek L, Long Z, Liang J, Lukin K, Leach SM, O'Connor B, Gerber AN, Hagman J, Roers A, Finkelman FD, Huang H. The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis. J Allergy Clin Immunol. 2018 10; 142(4):1173-1184.
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Robinson JL, Tzou KS, Parker AS, Heckman MG, Wu KJ, Hilton TW, Pisansky TM, Schild SE, Peterson JL, Vallow LA, Buskirk SJ. GATA2 expression and biochemical recurrence following salvage radiation therapy for relapsing prostate cancer. Br J Radiol. 2017 Jul; 90(1075):20170174.
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Li Y, Qi X, Liu B, Huang H. The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenance. J Immunol. 2015 May 01; 194(9):4328-38.
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Butko E, Distel M, Pouget C, Weijts B, Kobayashi I, Ng K, Mosimann C, Poulain FE, McPherson A, Ni CW, Stachura DL, Del Cid N, Esp?n-Palaz?n R, Lawson ND, Dorsky R, Clements WK, Traver D. Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo. Development. 2015 Mar 15; 142(6):1050-61.
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Wang T, Nandakumar V, Jiang XX, Jones L, Yang AG, Huang XF, Chen SY. The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation. Blood. 2013 Oct 17; 122(16):2812-22.
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Chang AN, Cantor AB, Fujiwara Y, Lodish MB, Droho S, Crispino JD, Orkin SH. GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis. Proc Natl Acad Sci U S A. 2002 Jul 09; 99(14):9237-42.
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