HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity.

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HIF-2alpha promotes hy

Loss of Grin2a causes

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HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity.

Gordan JD, Bertout JA, Hu CJ, Diehl JA, Simon MC. HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity. Cancer Cell. 2007 Apr; 11(4):335-47.

View in: PubMed

subject areas

Animals
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Basic Helix-Loop-Helix Transcription Factors
Cell Cycle
Cell Hypoxia
Cell Proliferation
Cells, Cultured
Chromatin Immunoprecipitation
Colonic Neoplasms
Embryo, Mammalian
Fibroblasts
Gene Expression Regulation, Neoplastic
Humans
Hypoxia-Inducible Factor 1, alpha Subunit
Mice
Mice, Knockout
NIH 3T3 Cells
Nuclear Proteins
Promoter Regions, Genetic
Protein Inhibitors of Activated STAT
Proto-Oncogene Proteins c-myc
Reverse Transcriptase Polymerase Chain Reaction
RNA, Messenger
Sp1 Transcription Factor
Trans-Activators
Transcription Factors
Transcription, Genetic
Ubiquitin-Protein Ligases
Von Hippel-Lindau Tumor Suppressor Protein

authors with profiles

Cheng Jun Hu

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