Structure of mediator of RhoA-dependent invasion (MRDI) explains its dual function as a metabolic enzyme and a mediator of cell invasion.

Templeton PD, Litman ES, Metzner SI, Ahn NG, Sousa MC. Structure of mediator of RhoA-dependent invasion (MRDI) explains its dual function as a metabolic enzyme and a mediator of cell invasion. Biochemistry. 2013 Aug 20; 52(33):5675-84.

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subject areas

Aldose-Ketose Isomerases
Amino Acid Sequence
Bacterial Proteins
Binding Sites
Blotting, Western
Catalytic Domain
Cell Line, Tumor
Crystallography, X-Ray
Genetic Complementation Test
Humans
Isomerases
Melanoma
Models, Molecular
Molecular Sequence Data
Mutation
Neoplasm Invasiveness
Protein Conformation
Ribulosephosphates
Sequence Homology, Amino Acid
Skin Neoplasms
Structure-Activity Relationship

authors with profiles

Natalie Ahn
Marcelo Carlos Sousa