 Epitopes
"Epitopes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sites on an antigen that interact with specific antibodies.
| Descriptor ID |
D000939
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| MeSH Number(s) |
D23.050.550
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| Concept/Terms |
Epitopes- Epitopes
- Antigenic Determinants
- Determinants, Antigenic
|
Below are MeSH descriptors whose meaning is more general than "Epitopes".
Below are MeSH descriptors whose meaning is more specific than "Epitopes".
This graph shows the total number of publications written about "Epitopes" by people in this website by year, and whether "Epitopes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 4 | 7 | | 1997 | 1 | 3 | 4 | | 1998 | 2 | 5 | 7 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 3 | 3 | | 2001 | 0 | 3 | 3 | | 2002 | 1 | 2 | 3 | | 2003 | 0 | 5 | 5 | | 2004 | 1 | 6 | 7 | | 2005 | 4 | 4 | 8 | | 2006 | 3 | 3 | 6 | | 2007 | 1 | 2 | 3 | | 2008 | 3 | 3 | 6 | | 2009 | 3 | 4 | 7 | | 2010 | 1 | 9 | 10 | | 2011 | 4 | 3 | 7 | | 2012 | 2 | 4 | 6 | | 2013 | 1 | 5 | 6 | | 2014 | 5 | 3 | 8 | | 2015 | 4 | 11 | 15 | | 2016 | 6 | 2 | 8 | | 2017 | 6 | 9 | 15 | | 2018 | 3 | 5 | 8 | | 2019 | 2 | 9 | 11 | | 2020 | 5 | 4 | 9 | | 2021 | 6 | 12 | 18 | | 2022 | 0 | 6 | 6 | | 2023 | 0 | 10 | 10 | | 2024 | 0 | 5 | 5 | | 2025 | 3 | 7 | 10 | | 2026 | 0 | 3 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Epitopes" by people in Profiles.
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DiLisio JE, Beard KS, Neef T, Miller SD, Wenzlau JM, Nakayama M, D'Antonio MA, Jamison BL, Nicholson KS, Baker RL, Brunetti TM, Gapin L, Haskins K. Antigen-specific immunotherapy with a CD4+ T cell neoepitope restrains CD8+ T cell differentiation in murine pancreatic islet grafts. Nat Commun. 2026 Mar 24; 17(1).
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Dai Y, Brouillard J, Jaycox JR, Yeon SM, Huck JD, Yandamuri SS, Zhong Z, O'Connor KC, Burnina I, Henkel C, LeMay AK, Lilov A, McGurk E, Morrill M, Parker L, Sackett T, Sandberg C, Sivasubramanian A, Geoghegan JC, Ring AM. Off-target reactivity in clinical monoclonal antibodies. Structure. 2026 May 07; 34(5):747-757.e5.
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Galindo G, Maejima D, DeRoo J, Burlingham SR, Fixen G, Morisaki T, Febvre HP, Hasbrook R, Zhao N, Ghosh S, Mayton EH, Snow CD, Geiss BJ, Ohkawa Y, Sato Y, Kimura H, Stasevich TJ. AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications. Sci Adv. 2026 Jan 02; 12(1):eadx8352.
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Ho AWS, Fukuzawa T, Koga H, Ohmine K, Kawauchi H, Muraoka M, Ikuta Y, Gupta G, Okuda M, Onami I, Ayabe M, Takeiri A, Konishi H, Sugawara Y, Usami S, Ito E, Shibahara N, Ozeki K, Wada Y, Hirako A, Takahashi N, Sampei Z, Haraya K, Murao N, Fujii T, Torizawa T, Shimada H, Igawa T. Long lasting complement neutralisation by RAY121, an engineered anti-C1s antibody with C1q displacement function. EBioMedicine. 2025 Dec; 122:106009.
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Delong T, Nakayama M. Epitope Hierarchy in Type 1 Diabetes Pathogenesis. Cold Spring Harb Perspect Med. 2025 Nov 03; 15(11).
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Bekkering ET, Yoo R, Hailemariam S, Heide F, Ivanochko D, Jackman M, Proellochs NI, Stoter R, van Gemert GJ, Maeda A, Yuguchi T, Wanders OT, van Daalen RC, Inklaar MR, Andrade CM, Jansen PWTC, Vermeulen M, Bousema T, Takashima E, Rubinstein JL, Kooij TWA, Jore MM, Julien JP. Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity. Immunity. 2025 Nov 11; 58(11):2899-2916.e10.
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Bernstein JS, Canon N, Schein CH, Braun W, Negi SS, Tchekmedyian R, Pozzoli M, Kim EH, Kulis MD, Vu T, Liu W, Chen X, Dreskin SC. Fine resolution of the N-terminal IgE-binding epitope of Ara h 2: Discovery of variants with enhanced IgE binding. J Allergy Clin Immunol. 2025 Aug; 156(2):385-393.
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Jia X, Wenzlau JM, Zhang C, Dong F, Waugh K, Leslie RD, Rewers MJ, Michels AW, Yu L. Strong Association of Autoantibodies Targeting Deamidated Extracellular Epitopes of Insulinoma Antigen-2 With Clinical Onset of Type 1 Diabetes. Diabetes. 2025 Apr 01; 74(4):544-553.
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Stumpf MM, Brunetti T, Davenport BJ, McCarthy MK, Morrison TE. Deep mutationally scanned CHIKV E3/E2 virus library maps viral amino acid preferences and predicts viral escape mutants of neutralizing CHIKV antibodies. J Virol. 2025 04 15; 99(4):e0008125.
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Gupta M, Khandelwal NK, Nelson A, Hwang P, Pourmal S, Bennett JL, Stroud RM. Structural basis of aquaporin-4 autoantibody binding in neuromyelitis optica. Sci Adv. 2025 Feb 21; 11(8):eadq7560.
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