 Epitopes
"Epitopes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sites on an antigen that interact with specific antibodies.
| Descriptor ID |
D000939
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| MeSH Number(s) |
D23.050.550
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| Concept/Terms |
Epitopes- Epitopes
- Antigenic Determinants
- Determinants, Antigenic
|
Below are MeSH descriptors whose meaning is more general than "Epitopes".
Below are MeSH descriptors whose meaning is more specific than "Epitopes".
This graph shows the total number of publications written about "Epitopes" by people in this website by year, and whether "Epitopes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 4 | 7 | | 1997 | 1 | 3 | 4 | | 1998 | 2 | 5 | 7 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 3 | 3 | | 2001 | 0 | 3 | 3 | | 2002 | 1 | 2 | 3 | | 2003 | 0 | 5 | 5 | | 2004 | 1 | 6 | 7 | | 2005 | 4 | 4 | 8 | | 2006 | 3 | 3 | 6 | | 2007 | 1 | 2 | 3 | | 2008 | 3 | 3 | 6 | | 2009 | 3 | 4 | 7 | | 2010 | 1 | 9 | 10 | | 2011 | 4 | 3 | 7 | | 2012 | 2 | 4 | 6 | | 2013 | 1 | 5 | 6 | | 2014 | 5 | 3 | 8 | | 2015 | 4 | 11 | 15 | | 2016 | 6 | 2 | 8 | | 2017 | 7 | 9 | 16 | | 2018 | 3 | 5 | 8 | | 2019 | 2 | 9 | 11 | | 2020 | 5 | 4 | 9 | | 2021 | 6 | 12 | 18 | | 2022 | 0 | 7 | 7 | | 2023 | 0 | 10 | 10 | | 2024 | 0 | 5 | 5 | | 2025 | 3 | 7 | 10 | | 2026 | 0 | 5 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "Epitopes" by people in Profiles.
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Stabell AC, Lee S, Park DJ, Lavine CL, Espinosa SM, Baharani VA, Patejak R, Nussenzweig MC, Caskey M, Seaman MS, Bieniasz PD, Hatziioannou T. Diverse paths to broadly neutralizing antibody escape among HIV-1 strains. Nat Microbiol. 2026 Jun; 11(6):1573-1584.
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Acciani M, Zyla D, Niemeyer G, Harkins S, Parekh D, Pawlack E, Lacarbonara D, Kansara D, Ackerman ME, Niewiesk S, Porotto M, Hastie KM, Saphire EO. Human neutralizing antibodies targeting the measles virus hemagglutinin and fusion surface proteins. Cell Host Microbe. 2026 Jun 10; 34(6):1067-1081.e12.
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Zyla DS, Della Marca R, Lacarbonara D, Niemeyer G, Zipursky G, Di Clemente L, Verbruggen MHL, van Dijk LLA, Ceh OM, Jonathan-Trakht G, Kalantarov G, Acciani M, Laterza G, Vyshenska D, Leedale C, Pawlack E, Hastie KM, Horvat B, de Swart RL, de Vries RD, Greninger AL, Niewiesk S, Ollmann Saphire E, Porotto M. Structural and mechanistic basis for antibody neutralization of the measles fusion protein. Nat Commun. 2026 Apr 06; 17(1).
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Dai Y, Brouillard J, Jaycox JR, Yeon SM, Huck JD, Yandamuri SS, Zhong Z, O'Connor KC, Burnina I, Henkel C, LeMay AK, Lilov A, McGurk E, Morrill M, Parker L, Sackett T, Sandberg C, Sivasubramanian A, Geoghegan JC, Ring AM. Off-target reactivity in clinical monoclonal antibodies. Structure. 2026 May 07; 34(5):747-757.e5.
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Galindo G, Maejima D, DeRoo J, Burlingham SR, Fixen G, Morisaki T, Febvre HP, Hasbrook R, Zhao N, Ghosh S, Mayton EH, Snow CD, Geiss BJ, Ohkawa Y, Sato Y, Kimura H, Stasevich TJ. AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications. Sci Adv. 2026 Jan 02; 12(1):eadx8352.
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Ho AWS, Fukuzawa T, Koga H, Ohmine K, Kawauchi H, Muraoka M, Ikuta Y, Gupta G, Okuda M, Onami I, Ayabe M, Takeiri A, Konishi H, Sugawara Y, Usami S, Ito E, Shibahara N, Ozeki K, Wada Y, Hirako A, Takahashi N, Sampei Z, Haraya K, Murao N, Fujii T, Torizawa T, Shimada H, Igawa T. Long lasting complement neutralisation by RAY121, an engineered anti-C1s antibody with C1q displacement function. EBioMedicine. 2025 Dec; 122:106009.
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Delong T, Nakayama M. Epitope Hierarchy in Type 1 Diabetes Pathogenesis. Cold Spring Harb Perspect Med. 2025 11 03; 15(11).
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Bekkering ET, Yoo R, Hailemariam S, Heide F, Ivanochko D, Jackman M, Proellochs NI, Stoter R, van Gemert GJ, Maeda A, Yuguchi T, Wanders OT, van Daalen RC, Inklaar MR, Andrade CM, Jansen PWTC, Vermeulen M, Bousema T, Takashima E, Rubinstein JL, Kooij TWA, Jore MM, Julien JP. Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity. Immunity. 2025 Nov 11; 58(11):2899-2916.e10.
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Bernstein JS, Canon N, Schein CH, Braun W, Negi SS, Tchekmedyian R, Pozzoli M, Kim EH, Kulis MD, Vu T, Liu W, Chen X, Dreskin SC. Fine resolution of the N-terminal IgE-binding epitope of Ara h 2: Discovery of variants with enhanced IgE binding. J Allergy Clin Immunol. 2025 Aug; 156(2):385-393.
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Jia X, Wenzlau JM, Zhang C, Dong F, Waugh K, Leslie RD, Rewers MJ, Michels AW, Yu L. Strong Association of Autoantibodies Targeting Deamidated Extracellular Epitopes of Insulinoma Antigen-2 With Clinical Onset of Type 1 Diabetes. Diabetes. 2025 Apr 01; 74(4):544-553.
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