 Epitopes
"Epitopes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sites on an antigen that interact with specific antibodies.
| Descriptor ID |
D000939
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| MeSH Number(s) |
D23.050.550
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| Concept/Terms |
Epitopes- Epitopes
- Antigenic Determinants
- Determinants, Antigenic
|
Below are MeSH descriptors whose meaning is more general than "Epitopes".
Below are MeSH descriptors whose meaning is more specific than "Epitopes".
This graph shows the total number of publications written about "Epitopes" by people in this website by year, and whether "Epitopes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 4 | 6 | | 1997 | 1 | 3 | 4 | | 1998 | 2 | 5 | 7 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 3 | 3 | | 2001 | 0 | 3 | 3 | | 2002 | 1 | 2 | 3 | | 2003 | 0 | 5 | 5 | | 2004 | 1 | 6 | 7 | | 2005 | 4 | 4 | 8 | | 2006 | 3 | 3 | 6 | | 2007 | 1 | 2 | 3 | | 2008 | 3 | 3 | 6 | | 2009 | 3 | 4 | 7 | | 2010 | 1 | 9 | 10 | | 2011 | 4 | 3 | 7 | | 2012 | 2 | 4 | 6 | | 2013 | 0 | 5 | 5 | | 2014 | 5 | 3 | 8 | | 2015 | 4 | 11 | 15 | | 2016 | 6 | 2 | 8 | | 2017 | 6 | 9 | 15 | | 2018 | 3 | 5 | 8 | | 2019 | 2 | 8 | 10 | | 2020 | 5 | 4 | 9 | | 2021 | 5 | 12 | 17 | | 2022 | 0 | 6 | 6 | | 2023 | 0 | 10 | 10 | | 2024 | 0 | 5 | 5 | | 2025 | 3 | 7 | 10 |
To return to the timeline, click here.
Below are the most recent publications written about "Epitopes" by people in Profiles.
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Ho AWS, Fukuzawa T, Koga H, Ohmine K, Kawauchi H, Muraoka M, Ikuta Y, Gupta G, Okuda M, Onami I, Ayabe M, Takeiri A, Konishi H, Sugawara Y, Usami S, Ito E, Shibahara N, Ozeki K, Wada Y, Hirako A, Takahashi N, Sampei Z, Haraya K, Murao N, Fujii T, Torizawa T, Shimada H, Igawa T. Long lasting complement neutralisation by RAY121, an engineered anti-C1s antibody with C1q displacement function. EBioMedicine. 2025 Dec; 122:106009.
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Delong T, Nakayama M. Epitope Hierarchy in Type 1 Diabetes Pathogenesis. Cold Spring Harb Perspect Med. 2025 Nov 03; 15(11).
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Bekkering ET, Yoo R, Hailemariam S, Heide F, Ivanochko D, Jackman M, Proellochs NI, Stoter R, van Gemert GJ, Maeda A, Yuguchi T, Wanders OT, van Daalen RC, Inklaar MR, Andrade CM, Jansen PWTC, Vermeulen M, Bousema T, Takashima E, Rubinstein JL, Kooij TWA, Jore MM, Julien JP. Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity. Immunity. 2025 Nov 11; 58(11):2899-2916.e10.
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Bernstein JS, Canon N, Schein CH, Braun W, Negi SS, Tchekmedyian R, Pozzoli M, Kim EH, Kulis MD, Vu T, Liu W, Chen X, Dreskin SC. Fine resolution of the N-terminal IgE-binding epitope of Ara h 2: Discovery of variants with enhanced IgE binding. J Allergy Clin Immunol. 2025 Aug; 156(2):385-393.
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Jia X, Wenzlau JM, Zhang C, Dong F, Waugh K, Leslie RD, Rewers MJ, Michels AW, Yu L. Strong Association of Autoantibodies Targeting Deamidated Extracellular Epitopes of Insulinoma Antigen-2 With Clinical Onset of Type 1 Diabetes. Diabetes. 2025 Apr 01; 74(4):544-553.
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Stumpf MM, Brunetti T, Davenport BJ, McCarthy MK, Morrison TE. Deep mutationally scanned CHIKV E3/E2 virus library maps viral amino acid preferences and predicts viral escape mutants of neutralizing CHIKV antibodies. J Virol. 2025 04 15; 99(4):e0008125.
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Gupta M, Khandelwal NK, Nelson A, Hwang P, Pourmal S, Bennett JL, Stroud RM. Structural basis of aquaporin-4 autoantibody binding in neuromyelitis optica. Sci Adv. 2025 Feb 21; 11(8):eadq7560.
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Greenhawt M, Albright D, Anvari S, Arends N, Arkwright PD, Bégin P, Blümchen K, Brown-Whitehorn T, Cassell H, Chan ES, Ciaccio CE, Deschildre A, Divaret-Chauveau A, Dorris S, Dorsey M, Du Toit G, Eiwegger T, Erlewyn-Lajeunesse M, Fleischer DM, Ford LS, Garcia-Lloret M, O'B Hourihane J, Jay N, Jones SM, Kim EH, Kloepfer K, Leonard S, Lezmi G, Lieberman J, Lomas J, Makhija M, O'Sullivan M, Parrish C, Peake J, Perrett KP, Petroni D, Pongracic JA, Quinn P, Robison RG, Sanders G, Schneider L, Sharma H, Sindher SB, Trujillo J, Turner PJ, Tuttle K, Upton J, Varshney P, Vickery BP, Vogelberg C, Wainstein B, Wang J, Wood R, Bee KJ, Campbell DE, Green TD, Rouissi R, Bahnson HT, Bois T, Sampson HA, Burks AW. Efficacy and Safety of Epicutaneous Immunotherapy in Peanut-Allergic Toddlers: Open-Label Extension to EPITOPE. J Allergy Clin Immunol Pract. 2025 May; 13(5):1176-1187.e7.
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Hastie KM, Salie ZL, Ke Z, Halfmann PJ, DeWald LE, McArdle S, Grinyó A, Davidson E, Schendel SL, Hariharan C, Norris MJ, Yu X, Chennareddy C, Xiong X, Heinrich M, Holbrook MR, Doranz B, Crozier I, Kawaoka Y, Branco LM, Kuhn JH, Briggs JAG, Worwa G, Davis CW, Ahmed R, Saphire EO. Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane. Nat Commun. 2025 Feb 03; 16(1):1293.
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Lin TH, Lee CD, Fernández-Quintero ML, Ferguson JA, Han J, Zhu X, Yu W, Guthmiller JJ, Krammer F, Wilson PC, Ward AB, Wilson IA. Structurally convergent antibodies derived from different vaccine strategies target the influenza virus HA anchor epitope with a subset of VH3 and VK3 genes. Nat Commun. 2025 Feb 02; 16(1):1268.
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