 Nomifensine
"Nomifensine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
| Descriptor ID |
D009627
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| MeSH Number(s) |
D03.633.100.531.535
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nomifensine".
Below are MeSH descriptors whose meaning is more specific than "Nomifensine".
This graph shows the total number of publications written about "Nomifensine" by people in this website by year, and whether "Nomifensine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nomifensine" by people in Profiles.
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Freund RK, Gerhardt GA, Marshall KE, Palmer MR. Differences in norepinephrine clearance in cerebellar slices from low-alcohol-sensitive and high-alcohol-sensitive rats. Alcohol. 2003 May; 30(1):9-18.
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Hoffer BJ, Leenders KL, Young D, Gerhardt G, Zerbe GO, Bygdeman M, Seiger A, Olson L, Str?mberg I, Freedman R. Eighteen-month course of two patients with grafts of fetal dopamine neurons for severe Parkinson's disease. Exp Neurol. 1992 Dec; 118(3):243-52.
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Pepper GA. Nomifensine (Merital): a second generation antidepressant. Nurse Pract. 1986 Feb; 11(2):72-4.
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