 5-Hydroxytryptophan
"5-Hydroxytryptophan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
| Descriptor ID |
D006916
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| MeSH Number(s) |
D12.125.072.050.850.479
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| Concept/Terms |
5-Hydroxytryptophan- 5-Hydroxytryptophan
- 5 Hydroxytryptophan
- Hydroxytryptophan
- Oxytryptophan
- Tryptophan, 5-Hydroxy-
- 5-Hydroxy- Tryptophan
- Tryptophan, 5 Hydroxy
- 5-HTP
- Oxitriptan
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Below are MeSH descriptors whose meaning is more general than "5-Hydroxytryptophan".
Below are MeSH descriptors whose meaning is more specific than "5-Hydroxytryptophan".
This graph shows the total number of publications written about "5-Hydroxytryptophan" by people in this website by year, and whether "5-Hydroxytryptophan" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "5-Hydroxytryptophan" by people in Profiles.
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Russo AM, Payet JM, Kent S, Lesku JA, Lowry CA, Hale MW. Acute treatment with 5-hydroxytryptophan increases social approach behaviour but does not activate serotonergic neurons in the dorsal raphe nucleus in juvenile male BALB/c mice: A model of human disorders with deficits of sociability. J Psychopharmacol. 2022 07; 36(7):806-818.
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Bubak AN, Watt MJ, Renner KJ, Luman AA, Costabile JD, Sanders EJ, Grace JL, Swallow JG. Sex differences in aggression: Differential roles of 5-HT2, neuropeptide F and tachykinin. PLoS One. 2019; 14(1):e0203980.
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Payet JM, Burnie E, Sathananthan NJ, Russo AM, Lawther AJ, Kent S, Lowry CA, Hale MW. Exposure to Acute and Chronic Fluoxetine has Differential Effects on Sociability and Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus of Juvenile Male BALB/c Mice. Neuroscience. 2018 08 21; 386:1-15.
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Porter EB, Polaski JT, Morck MM, Batey RT. Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors. Nat Chem Biol. 2017 03; 13(3):295-301.
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Bubak AN, Renner KJ, Swallow JG. Heightened serotonin influences contest outcome and enhances expression of high-intensity aggressive behaviors. Behav Brain Res. 2014 Feb 01; 259:137-42.
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Bubak AN, Swallow JG, Renner KJ. Whole brain monoamine detection and manipulation in a stalk-eyed fly. J Neurosci Methods. 2013 Sep 30; 219(1):124-30.
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Yang R, Montoya A, Bond A, Walton J, Kinnamon JC. Immunocytochemical analysis of P2X2 in rat circumvallate taste buds. BMC Neurosci. 2012 May 23; 13:51.
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Freedman RR. Treatment of menopausal hot flashes with 5-hydroxytryptophan. Maturitas. 2010 Apr; 65(4):383-5.
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Evans AK, Heerkens JL, Lowry CA. Acoustic stimulation in vivo and corticotropin-releasing factor in vitro increase tryptophan hydroxylase activity in the rat caudal dorsal raphe nucleus. Neurosci Lett. 2009 May 08; 455(1):36-41.
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Evans AK, Reinders N, Ashford KA, Christie IN, Wakerley JB, Lowry CA. Evidence for serotonin synthesis-dependent regulation of in vitro neuronal firing rates in the midbrain raphe complex. Eur J Pharmacol. 2008 Aug 20; 590(1-3):136-49.
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