 Interleukin-13 Receptor alpha1 Subunit
"Interleukin-13 Receptor alpha1 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin receptor subunit with specificity for INTERLEUKIN-13. It dimerizes with the INTERLEUKIN-4 RECEPTOR ALPHA SUBUNIT to form the TYPE II INTERLEUKIN-4 RECEPTOR which has specificity for both INTERLEUKIN-4 and INTERLEUKIN-13. Signaling of this receptor subunit occurs through the interaction of its cytoplasmic domain with JANUS KINASES such as the TYK2 KINASE.
| Descriptor ID |
D053661
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| MeSH Number(s) |
D12.776.543.750.705.852.420.360.600.500 D12.776.543.750.705.852.420.600.800.500
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| Concept/Terms |
Interleukin-13 Receptor alpha1 Subunit- Interleukin-13 Receptor alpha1 Subunit
- Interleukin 13 Receptor alpha1 Subunit
- Interleukin-4, 13 Receptor Shared Subunit
- Interleukin 4, 13 Receptor Shared Subunit
- Interleukin-13 Receptor alpha1 Chain
- Interleukin 13 Receptor alpha1 Chain
- Antigens, CD213a1
- CD213a1 Antigens
- IL-13Ralpha1
- CD213a1 Antigen
- Antigen, CD213a1
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Below are MeSH descriptors whose meaning is more general than "Interleukin-13 Receptor alpha1 Subunit".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-4 [D12.776.543.750.705.852.420.360]
- Receptors, Interleukin-4, Type II [D12.776.543.750.705.852.420.360.600]
- Interleukin-13 Receptor alpha1 Subunit [D12.776.543.750.705.852.420.360.600.500]
- Receptors, Interleukin-13 [D12.776.543.750.705.852.420.600]
- Receptors, Interleukin-4, Type II [D12.776.543.750.705.852.420.600.800]
- Interleukin-13 Receptor alpha1 Subunit [D12.776.543.750.705.852.420.600.800.500]
Below are MeSH descriptors whose meaning is more specific than "Interleukin-13 Receptor alpha1 Subunit".
This graph shows the total number of publications written about "Interleukin-13 Receptor alpha1 Subunit" by people in this website by year, and whether "Interleukin-13 Receptor alpha1 Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-13 Receptor alpha1 Subunit" by people in Profiles.
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Karo-Atar D, Bordowitz A, Wand O, Pasmanik-Chor M, Fernandez IE, Itan M, Frenkel R, Herbert DR, Finkelman FD, Eickelberg O, Munitz A. A protective role for IL-13 receptor a 1 in bleomycin-induced pulmonary injury and repair. Mucosal Immunol. 2016 Jan; 9(1):240-53.
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Madala SK, Dolan MA, Sharma D, Ramalingam TR, Wilson MS, Mentink-Kane MM, Masison DC, Wynn TA. Mapping mouse IL-13 binding regions using structure modeling, molecular docking, and high-density peptide microarray analysis. Proteins. 2011 Jan; 79(1):282-93.
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Hecker M, Zaslona Z, Kwapiszewska G, Niess G, Zakrzewicz A, Hergenreider E, Wilhelm J, Marsh LM, Sedding D, Klepetko W, Lohmeyer J, Dimmeler S, Seeger W, Weissmann N, Schermuly RT, Kneidinger N, Eickelberg O, Morty RE. Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension. Am J Respir Crit Care Med. 2010 Sep 15; 182(6):805-18.
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Jakubzick C, Choi ES, Carpenter KJ, Kunkel SL, Evanoff H, Martinez FJ, Flaherty KR, Toews GB, Colby TV, Travis WD, Joshi BH, Puri RK, Hogaboam CM. Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia. Am J Pathol. 2004 Jun; 164(6):1989-2001.
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Jakubzick C, Choi ES, Kunkel SL, Evanoff H, Martinez FJ, Puri RK, Flaherty KR, Toews GB, Colby TV, Kazerooni EA, Gross BH, Travis WD, Hogaboam CM. Augmented pulmonary IL-4 and IL-13 receptor subunit expression in idiopathic interstitial pneumonia. J Clin Pathol. 2004 May; 57(5):477-86.
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Kolodsick JE, Toews GB, Jakubzick C, Hogaboam C, Moore TA, McKenzie A, Wilke CA, Chrisman CJ, Moore BB. Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts. J Immunol. 2004 Apr 01; 172(7):4068-76.
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Jakubzick C, Kunkel SL, Puri RK, Hogaboam CM. Therapeutic targeting of IL-4- and IL-13-responsive cells in pulmonary fibrosis. Immunol Res. 2004; 30(3):339-49.
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Jakubzick C, Choi ES, Joshi BH, Keane MP, Kunkel SL, Puri RK, Hogaboam CM. Therapeutic attenuation of pulmonary fibrosis via targeting of IL-4- and IL-13-responsive cells. J Immunol. 2003 Sep 01; 171(5):2684-93.
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Jakubzick C, Choi ES, Kunkel SL, Joshi BH, Puri RK, Hogaboam CM. Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts. Am J Pathol. 2003 May; 162(5):1475-86.
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Blease K, Jakubzick C, Schuh JM, Joshi BH, Puri RK, Hogaboam CM. IL-13 fusion cytotoxin ameliorates chronic fungal-induced allergic airway disease in mice. J Immunol. 2001 Dec 01; 167(11):6583-92.
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