 Isoelectric Focusing
"Isoelectric Focusing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Electrophoresis in which a pH gradient is established in a gel medium and proteins migrate until they reach the site (or focus) at which the pH is equal to their isoelectric point.
| Descriptor ID |
D007525
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| MeSH Number(s) |
E05.196.401.663 E05.301.300.663
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Isoelectric Focusing".
Below are MeSH descriptors whose meaning is more specific than "Isoelectric Focusing".
This graph shows the total number of publications written about "Isoelectric Focusing" by people in this website by year, and whether "Isoelectric Focusing" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 2 | 3 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Isoelectric Focusing" by people in Profiles.
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Yu Y, Jin D, Hu S, Zhang Y, Zheng X, Zheng J, Liao M, Chen X, Graner M, Liu H, Jin Q. A novel tuberculosis antigen identified from human tuberculosis granulomas. Mol Cell Proteomics. 2015 Apr; 14(4):1093-103.
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Pallotta V, D'Alessandro A, Rinalducci S, Zolla L. Native protein complexes in the cytoplasm of red blood cells. J Proteome Res. 2013 Jul 05; 12(7):3529-46.
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Bornhorst JA, Greene DN, Ashwood ER, Grenache DG. a1-Antitrypsin phenotypes and associated serum protein concentrations in a large clinical population. Chest. 2013 Apr; 143(4):1000-1008.
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Patel BB, Barrero CA, Braverman A, Kim PD, Jones KA, Chen DE, Bowler RP, Merali S, Kelsen SG, Yeung AT. Assessment of two immunodepletion methods: off-target effects and variations in immunodepletion efficiency may confound plasma proteomics. J Proteome Res. 2012 Dec 07; 11(12):5947-58.
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Otsuka M, Marks SA, Winnica DE, Amoscato AA, Pearce LL, Peterson J. Covalent modifications of hemoglobin by nitrite anion: formation kinetics and properties of nitrihemoglobin. Chem Res Toxicol. 2010 Nov 15; 23(11):1786-95.
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Bornhorst JA, Calderon FR, Procter M, Tang W, Ashwood ER, Mao R. Genotypes and serum concentrations of human alpha-1-antitrypsin "P" protein variants in a clinical population. J Clin Pathol. 2007 Oct; 60(10):1124-8.
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Belin RJ, Sumandea MP, Kobayashi T, Walker LA, Rundell VL, Urboniene D, Yuzhakova M, Ruch SH, Geenen DL, Solaro RJ, de Tombe PP. Left ventricular myofilament dysfunction in rat experimental hypertrophy and congestive heart failure. Am J Physiol Heart Circ Physiol. 2006 Nov; 291(5):H2344-53.
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Kobayashi T, Yang X, Walker LA, Van Breemen RB, Solaro RJ. A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C. J Mol Cell Cardiol. 2005 Jan; 38(1):213-8.
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Bernard KR, Jonscher KR, Resing KA, Ahn NG. Methods in functional proteomics: two-dimensional polyacrylamide gel electrophoresis with immobilized pH gradients, in-gel digestion and identification of proteins by mass spectrometry. Methods Mol Biol. 2004; 250:263-82.
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Kabuyama Y, Polvinen KK, Resing KA, Ahn NG. Two-dimensional gel electrophoresis for the identification of signaling targets. Methods Mol Biol. 2004; 284:37-49.
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