 Integrin alpha5beta1
"Integrin alpha5beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin found in FIBROBLASTS; PLATELETS; MONOCYTES, and LYMPHOCYTES. Integrin alpha5beta1 is the classical receptor for FIBRONECTIN, but it also functions as a receptor for LAMININ and several other EXTRACELLULAR MATRIX PROTEINS.
| Descriptor ID |
D039081
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| MeSH Number(s) |
D12.776.395.550.625.379 D12.776.543.550.625.379 D12.776.543.750.705.408.530.750 D12.776.543.750.705.408.850.349 D12.776.543.750.705.675.460 D12.776.543.750.705.876.374
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| Concept/Terms |
Integrin alpha5beta1- Integrin alpha5beta1
- alpha5beta1, Integrin
- Integrin alpha-5 beta-1
- Integrin alpha 5 beta 1
- alpha-5 beta-1, Integrin
- beta-1, Integrin alpha-5
- Platelet Glycoprotein Ic-IIa
- Glycoprotein Ic-IIa, Platelet
- Ic-IIa, Platelet Glycoprotein
- Platelet Glycoprotein Ic IIa
- VLA-5
- VLA-5 Receptors
- VLA 5 Receptors
- Fibronectin Receptor
- Receptor, Fibronectin
- Receptors, VLA-5
- Receptors, VLA 5
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Below are MeSH descriptors whose meaning is more general than "Integrin alpha5beta1".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha5beta1".
This graph shows the total number of publications written about "Integrin alpha5beta1" by people in this website by year, and whether "Integrin alpha5beta1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 | | 2010 | 1 | 1 | 2 | | 2015 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Integrin alpha5beta1" by people in Profiles.
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Gumina DL, Ji S, Flockton A, McPeak K, Stich D, Moldovan R, Su EJ. Dysregulation of integrin av?3 and a5?1 impedes migration of placental endothelial cells in fetal growth restriction. Development. 2022 10 01; 149(19):dev200717.
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Das L, Gard JMC, Prekeris R, Nagle RB, Morrissey C, Knudsen BS, Miranti CK, Cress AE. Novel Regulation of Integrin Trafficking by Rab11-FIP5 in Aggressive Prostate Cancer. Mol Cancer Res. 2018 08; 16(8):1319-1331.
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Osborne DG, Phillips-Krawczak CA, Billadeau DD. Monitoring receptor trafficking following retromer and WASH deregulation. Methods Cell Biol. 2015; 130:199-213.
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Mise N, Savai R, Yu H, Schwarz J, Kaminski N, Eickelberg O. Zyxin is a transforming growth factor-? (TGF-?)/Smad3 target gene that regulates lung cancer cell motility via integrin a5?1. J Biol Chem. 2012 Sep 07; 287(37):31393-405.
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Zhou Q, Pardo A, K?nigshoff M, Eickelberg O, Budinger GR, Thavarajah K, Gottardi CJ, Jones J, Varga J, Selman M, Sznajder JI, Raj JU, Zhou G. Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis. FASEB J. 2011 Sep; 25(9):3032-44.
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McKenzie JA, Liu T, Goodson AG, Grossman D. Survivin enhances motility of melanoma cells by supporting Akt activation and {alpha}5 integrin upregulation. Cancer Res. 2010 Oct 15; 70(20):7927-37.
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Gu X, Masters KS. Regulation of valvular interstitial cell calcification by adhesive peptide sequences. J Biomed Mater Res A. 2010 Jun 15; 93(4):1620-30.
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Hartney JM, Brown J, Chu HW, Chang LY, Pelanda R, Torres RM. Arhgef1 regulates alpha5beta1 integrin-mediated matrix metalloproteinase expression and is required for homeostatic lung immunity. Am J Pathol. 2010 Mar; 176(3):1157-68.
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Salinas CN, Anseth KS. The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities. Biomaterials. 2008 May; 29(15):2370-7.
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