 beta-Lactamases
"beta-Lactamases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
| Descriptor ID |
D001618
|
| MeSH Number(s) |
D08.811.277.087.180
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "beta-Lactamases".
Below are MeSH descriptors whose meaning is more specific than "beta-Lactamases".
This graph shows the total number of publications written about "beta-Lactamases" by people in this website by year, and whether "beta-Lactamases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 3 | 0 | 3 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2022 | 1 | 2 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "beta-Lactamases" by people in Profiles.
-
Bennett JA, Steward LR, Rudolph J, Voss AP, Aydin H. The structure of the human LACTB filament reveals the mechanisms of assembly and membrane binding. PLoS Biol. 2022 12; 20(12):e3001899.
-
Molina KC, Bajrovic V, Bonomo RA. Carbapenemase-producing Enterobacterales in solid organ transplantation: Tip of the iceberg? Transpl Infect Dis. 2022 Apr; 24(2):e13780.
-
Dousa KM, Nguyen DC, Kurz SG, Taracila MA, Bethel CR, Schinabeck W, Kreiswirth BN, Brown ST, Boom WH, Hotchkiss RS, Remy KE, Jacono FJ, Daley CL, Holland SM, Miller AA, Bonomo RA. Inhibiting Mycobacterium abscessus Cell Wall Synthesis: Using a Novel Diazabicyclooctane ?-Lactamase Inhibitor To Augment ?-Lactam Action. mBio. 2022 02 22; 13(1):e0352921.
-
Snyder BM, Montague BT, Anandan S, Madabhushi AG, Pragasam AK, Verghese VP, Balaji V, Sim?es EAF. Risk factors and epidemiologic predictors of blood stream infections with New Delhi Metallo-b-lactamase (NDM-1) producing Enterobacteriaceae. Epidemiol Infect. 2019 01; 147:e137.
-
Young HL, Croyle C, Janelle SJ, Knepper BC, Kurtz J, Miller A, Reese SM, Schutz K, Bamberg WM. Collaboration for containment: Detection of OXA-23-like carbapenamase-producing Acinetobacter baumannii in Colorado. Infect Control Hosp Epidemiol. 2018 10; 39(10):1273-1274.
-
Klesmith JR, Bacik JP, Wrenbeck EE, Michalczyk R, Whitehead TA. Trade-offs between enzyme fitness and solubility illuminated by deep mutational scanning. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):2265-2270.
-
Zhu M, Yang G, Li A, Zong L, Dong Z, Lu J, Zhang K, Cheng C, Chang Q, Wu X, Ying J, Li X, Ding L, Zheng H, Yu J, Ying J, Xu T, Yi H, Li P, Li K, Wu S, Bao Q, Wang J. Identification and molecular characterization of Escherichia coli blaSHV genes in a Chinese teaching hospital. Gene. 2017 Feb 05; 600:29-35.
-
McCollister B, Kotter CV, Frank DN, Washburn T, Jobling MG. Whole-Genome Sequencing Identifies In Vivo Acquisition of a blaCTX-M-27-Carrying IncFII Transmissible Plasmid as the Cause of Ceftriaxone Treatment Failure for an Invasive Salmonella enterica Serovar Typhimurium Infection. Antimicrob Agents Chemother. 2016 12; 60(12):7224-7235.
-
Yi H, Choi JM, Hwang J, Prati F, Cao TP, Lee SH, Kim HS. High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A ?-lactamase, PenL. Sci Rep. 2016 11 09; 6:36527.
-
Wrenbeck EE, Klesmith JR, Stapleton JA, Adeniran A, Tyo KE, Whitehead TA. Plasmid-based one-pot saturation mutagenesis. Nat Methods. 2016 Nov; 13(11):928-930.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|