 beta-Lactamases
"beta-Lactamases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
| Descriptor ID |
D001618
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| MeSH Number(s) |
D08.811.277.087.180
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "beta-Lactamases".
Below are MeSH descriptors whose meaning is more specific than "beta-Lactamases".
This graph shows the total number of publications written about "beta-Lactamases" by people in this website by year, and whether "beta-Lactamases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 3 | 0 | 3 | | 2015 | 1 | 1 | 2 | | 2016 | 3 | 1 | 4 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 5 | 6 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "beta-Lactamases" by people in Profiles.
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Shin E, Dousa KM, Taracila MA, Bethel CR, Nantongo M, Nguyen DC, Akusobi C, Kurz SG, Plummer MS, Daley CL, Holland SM, Rubin EJ, Bulitta JB, Boom WH, Kreiswirth BN, Bonomo RA. Durlobactam in combination with ?-lactams to combat Mycobacterium abscessus. Antimicrob Agents Chemother. 2025 Feb 13; 69(2):e0117424.
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Frost HM, Keith A, Fletcher DR, Sebastian T, Dominguez SR, Kurtz M, Parker SK, Wilson ML, Jenkins TC. Clinical Outcomes Associated with Amoxicillin Treatment for Acute Otitis Media in Children. J Pediatric Infect Dis Soc. 2024 Mar 19; 13(3):203-210.
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Asempa TE, Bobenchik AM, Bourassa L, Clark AE, Hatch MT, Huse HK, Martin IW, Mochon AB, Munson E, Sfeir MM, Srodon M, Wang Y, Nicolau DP. Antimicrobial Activity of Tebipenem and Comparators against Enterobacterales from diverse Outpatient Centers and Nursing Homes in the United States. Int J Antimicrob Agents. 2023 Mar; 61(3):106733.
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Bennett JA, Steward LR, Rudolph J, Voss AP, Aydin H. The structure of the human LACTB filament reveals the mechanisms of assembly and membrane binding. PLoS Biol. 2022 12; 20(12):e3001899.
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Bulens SN, Reses HE, Ansari UA, Grass JE, Carmon C, Albrecht V, Lawsin A, McAllister G, Daniels J, Lee YK, Yi S, See I, Jacob JT, Bower CW, Wilson L, Vaeth E, Lynfield R, Vagnone PS, Shaw KM, Dumyati G, Tsay R, Phipps EC, Bamberg W, Janelle SJ, Beldavs ZG, Cassidy PM, Kainer M, Muleta D, Mounsey JT, Laufer-Halpin A, Karlsson M, Lutgring JD, Walters MS. Carbapenem-Resistant enterobacterales in individuals with and without health care risk factors -Emerging infections program, United States, 2012-2015. Am J Infect Control. 2023 01; 51(1):70-77.
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Duffy N, Karlsson M, Reses HE, Campbell D, Daniels J, Stanton RA, Janelle SJ, Schutz K, Bamberg W, Rebolledo PA, Bower C, Blakney R, Jacob JT, Phipps EC, Flores KG, Dumyati G, Kopin H, Tsay R, Kainer MA, Muleta D, Byrd-Warner B, Grass JE, Lutgring JD, Rasheed JK, Elkins CA, Magill SS, See I. Epidemiology of extended-spectrum ?-lactamase-producing Enterobacterales in five US sites participating in the Emerging Infections Program, 2017. Infect Control Hosp Epidemiol. 2022 11; 43(11):1586-1594.
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Molina KC, Bajrovic V, Bonomo RA. Carbapenemase-producing Enterobacterales in solid organ transplantation: Tip of the iceberg? Transpl Infect Dis. 2022 Apr; 24(2):e13780.
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Ho TD, Nauta KM, Luhmann EK, Radoshevich L, Ellermeier CD. Identification of the Extracytoplasmic Function s Factor sP Regulon in Bacillus thuringiensis. mSphere. 2022 02 23; 7(1):e0096721.
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Dousa KM, Nguyen DC, Kurz SG, Taracila MA, Bethel CR, Schinabeck W, Kreiswirth BN, Brown ST, Boom WH, Hotchkiss RS, Remy KE, Jacono FJ, Daley CL, Holland SM, Miller AA, Bonomo RA. Inhibiting Mycobacterium abscessus Cell Wall Synthesis: Using a Novel Diazabicyclooctane ?-Lactamase Inhibitor To Augment ?-Lactam Action. mBio. 2022 02 22; 13(1):e0352921.
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Jonas D, Reuter S, Klassen S, Weber S, Buck M, Giani T, Rossolini GM, Grundmann H. Evaluation of the BD Phoenix CPO detect panel for prediction of Ambler class carbapenemases. Sci Rep. 2021 06 23; 11(1):13150.
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