 Coenzyme A Ligases
"Coenzyme A Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the formation of acyl-CoA derivatives. EC 6.2.1.
| Descriptor ID |
D003066
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| MeSH Number(s) |
D08.811.464.267.500
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| Concept/Terms |
Coenzyme A Ligases- Coenzyme A Ligases
- Ligases, Coenzyme A
- Coenzyme A Synthetases
- Synthetases, Coenzyme A
- Acid-Thiol Ligases
- Acid Thiol Ligases
- Ligases, Acid-Thiol
- Co A Ligases
- Ligases, Co A
- Acyl Coenzyme A Synthetases
- Acyl CoA Synthetases
- CoA Synthetases, Acyl
- Synthetases, Acyl CoA
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Below are MeSH descriptors whose meaning is more general than "Coenzyme A Ligases".
Below are MeSH descriptors whose meaning is more specific than "Coenzyme A Ligases".
This graph shows the total number of publications written about "Coenzyme A Ligases" by people in this website by year, and whether "Coenzyme A Ligases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 1 | 1 | | 2016 | 1 | 1 | 2 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Coenzyme A Ligases" by people in Profiles.
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Murphy CS, Fairfield H, DeMambro VE, Fadel S, Gartner CA, Karam M, Potts C, Rodriguez P, Qiang YW, Hamidi H, Guan X, Vary CPH, Reagan MR. Inhibition of acyl-CoA synthetase long-chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction. Mol Oncol. 2025 Jun; 19(6):1687-1706.
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Del Rio Flores A, Twigg FF, Du Y, Cai W, Aguirre DQ, Sato M, Dror MJ, Narayanamoorthy M, Geng J, Zill NA, Zhai R, Zhang W. Biosynthesis of triacsin featuring an N-hydroxytriazene pharmacophore. Nat Chem Biol. 2021 12; 17(12):1305-1313.
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Alicea GM, Rebecca VW, Goldman AR, Fane ME, Douglass SM, Behera R, Webster MR, Kugel CH, Ecker BL, Caino MC, Kossenkov AV, Tang HY, Frederick DT, Flaherty KT, Xu X, Liu Q, Gabrilovich DI, Herlyn M, Blair IA, Schug ZT, Speicher DW, Weeraratna AT. Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2. Cancer Discov. 2020 09; 10(9):1282-1295.
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Pennington ER, Sullivan EM, Fix A, Dadoo S, Zeczycki TN, DeSantis A, Schlattner U, Coleman RA, Chicco AJ, Brown DA, Shaikh SR. Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin. J Biol Chem. 2018 10 12; 293(41):15933-15946.
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Cheng L, Ge M, Lan Z, Ma Z, Chi W, Kuang W, Sun K, Zhao X, Liu Y, Feng Y, Huang Y, Luo M, Li L, Zhang B, Hu X, Xu L, Liu X, Huo Y, Deng H, Yang J, Xi Q, Zhang Y, Siegenthaler JA, Chen L. Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity. Arch Toxicol. 2018 Jan; 92(1):469-485.
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Xuan S, Sussel L. GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling. Development. 2016 Mar 01; 143(5):780-6.
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Lager S, Ramirez VI, Gaccioli F, Jang B, Jansson T, Powell TL. Protein expression of fatty acid transporter 2 is polarized to the trophoblast basal plasma membrane and increased in placentas from overweight/obese women. Placenta. 2016 Apr; 40:60-6.
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Grevengoed TJ, Martin SA, Katunga L, Cooper DE, Anderson EJ, Murphy RC, Coleman RA. Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. J Lipid Res. 2015 Aug; 56(8):1572-82.
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Gulick AM, Starai VJ, Horswill AR, Homick KM, Escalante-Semerena JC. The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A. Biochemistry. 2003 Mar 18; 42(10):2866-73.
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Dimitroulakos J, Marhin WH, Tokunaga J, Irish J, Gullane P, Penn LZ, Kamel-Reid S. Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas. Neoplasia. 2002 Jul-Aug; 4(4):337-46.
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