 Peptide Nucleic Acids
"Peptide Nucleic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers.
| Descriptor ID |
D020135
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| MeSH Number(s) |
D13.695.578.424.550
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Peptide Nucleic Acids".
Below are MeSH descriptors whose meaning is more specific than "Peptide Nucleic Acids".
This graph shows the total number of publications written about "Peptide Nucleic Acids" by people in this website by year, and whether "Peptide Nucleic Acids" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 2 | 0 | 2 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Peptide Nucleic Acids" by people in Profiles.
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McCollum CR, Courtney CM, O'Connor NJ, Aunins TR, Jordan TX, Rogers KL, Brindley S, Brown JM, Nagpal P, Chatterjee A. Safety and Biodistribution of Nanoligomers Targeting the SARS-CoV-2 Genome for the Treatment of COVID-19. ACS Biomater Sci Eng. 2023 03 13; 9(3):1656-1671.
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Eller KA, Aunins TR, Courtney CM, Campos JK, Otoupal PB, Erickson KE, Madinger NE, Chatterjee A. Facile accelerated specific therapeutic (FAST) platform develops antisense?therapies to counter multidrug-resistant bacteria. Commun Biol. 2021 03 12; 4(1):331.
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Pienko T, Czarnecki J, R?wnicki M, Wojciechowska M, Wierzba AJ, Gryko D, Bartosik D, Trylska J. Vitamin B12-peptide nucleic acids use the BtuB receptor to pass through the Escherichia?coli outer membrane. Biophys J. 2021 02 16; 120(4):725-737.
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Wierzba AJ, Wojciechowska M, Trylska J, Gryko D. Vitamin B12?- Peptide Nucleic Acid Conjugates. Methods Mol Biol. 2021; 2355:65-82.
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Cartwright IM. Modified PNA Telomere and Centromere FISH Protocols. Methods Mol Biol. 2019; 1984:101-105.
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Cartwright IM, Haskins JS, Kato TA. PNA Telomere and Centromere FISH Staining for Accurate Analysis of Radiation-Induced Chromosomal Aberrations. Methods Mol Biol. 2019; 1984:95-100.
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Wierzba AJ, Maximova K, Wincenciuk A, R?wnicki M, Wojciechowska M, Nex? E, Trylska J, Gryko D. Does a Conjugation Site Affect Transport of Vitamin B12 -Peptide Nucleic Acid Conjugates into Bacterial Cells? Chemistry. 2018 Dec 12; 24(70):18772-18778.
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R?wnicki M, Wojciechowska M, Wierzba AJ, Czarnecki J, Bartosik D, Gryko D, Trylska J. Vitamin B12 as a carrier of peptide nucleic acid (PNA) into bacterial cells. Sci Rep. 2017 08 09; 7(1):7644.
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Pienko T, Wierzba AJ, Wojciechowska M, Gryko D, Trylska J. Conformational Dynamics of Cyanocobalamin and Its Conjugates with Peptide Nucleic Acids. J Phys Chem B. 2017 04 13; 121(14):2968-2979.
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Brown PN, Yin H. PNA-based microRNA inhibitors elicit anti-inflammatory effects in microglia cells. Chem Commun (Camb). 2013 May 14; 49(39):4415-7.
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