PDZ Domains
"PDZ Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein interaction domains of about 70-90 amino acid residues, named after a common structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains are involved in the recruitment and interaction of proteins, and aid the formation of protein scaffolds and signaling networks. This is achieved by sequence-specific binding between a PDZ domain in one protein and a PDZ motif in another protein.
Descriptor ID |
D054731
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MeSH Number(s) |
G02.111.570.820.709.275.750.500.500
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Concept/Terms |
PDZ Domains- PDZ Domains
- Domain, PDZ
- Domains, PDZ
- PDZ Domain
- PDZ Interaction Domains
- Domain, PDZ Interaction
- Domains, PDZ Interaction
- Interaction Domain, PDZ
- Interaction Domains, PDZ
- PDZ Interaction Domain
- PSD95-DLG-ZO1 Domains
- Domain, PSD95-DLG-ZO1
- Domains, PSD95-DLG-ZO1
- PSD95 DLG ZO1 Domains
- PSD95-DLG-ZO1 Domain
- DLG Homology Repeats Domains
- GLGF Repeats Domains
- Domain, GLGF Repeats
- Domains, GLGF Repeats
- GLGF Repeats Domain
- Repeats Domain, GLGF
- Repeats Domains, GLGF
- DHR Domains
- DHR Domain
- Domain, DHR
- Domains, DHR
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Below are MeSH descriptors whose meaning is more general than "PDZ Domains".
Below are MeSH descriptors whose meaning is more specific than "PDZ Domains".
This graph shows the total number of publications written about "PDZ Domains" by people in this website by year, and whether "PDZ Domains" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2011 | 0 | 1 | 1 | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "PDZ Domains" by people in Profiles.
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Al-Saleem J, Dirksen WP, Martinez MP, Shkriabai N, Kvaratskhelia M, Ratner L, Green PL. HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1. PLoS One. 2019; 14(3):e0214059.
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Lin L, Sun W, Kung F, Dell'Acqua ML, Hoffman DA. AKAP79/150 impacts intrinsic excitability of hippocampal neurons through phospho-regulation of A-type K+ channel trafficking. J Neurosci. 2011 Jan 26; 31(4):1323-32.
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