 GA-Binding Protein Transcription Factor
"GA-Binding Protein Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterotetrameric transcription factor composed of two distinct proteins. Its name refers to the fact it binds to DNA sequences rich in GUANINE and ADENINE. GA-binding protein integrates a variety of SIGNAL TRANSDUCTION PATHWAYS and regulates expression of GENES involved in CELL CYCLE control, PROTEIN BIOSYNTHESIS, and cellular METABOLISM.
| Descriptor ID |
D051268
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| MeSH Number(s) |
D12.776.260.615.249 D12.776.930.618.249
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| Concept/Terms |
GA-Binding Protein Transcription Factor- GA-Binding Protein Transcription Factor
- GA Binding Protein Transcription Factor
- Nuclear Respiratory Factor-2
- Respiratory Factor-2, Nuclear
- Nuclear Respiratory Factor 2
- GA-Binding Protein
- GA Binding Protein
- GABP Transcription Factor
- Transcription Factor, GABP
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Below are MeSH descriptors whose meaning is more general than "GA-Binding Protein Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GA-Binding Protein Transcription Factor".
This graph shows the total number of publications written about "GA-Binding Protein Transcription Factor" by people in this website by year, and whether "GA-Binding Protein Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "GA-Binding Protein Transcription Factor" by people in Profiles.
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Stern JL, Theodorescu D, Vogelstein B, Papadopoulos N, Cech TR. Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers. Genes Dev. 2015 Nov 01; 29(21):2219-24.
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Maier H, Ostraat R, Parenti S, Fitzsimmons D, Abraham LJ, Garvie CW, Hagman J. Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene transcription by Pax-5 (BSAP). Nucleic Acids Res. 2003 Oct 01; 31(19):5483-9.
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Schweppe RE, Melton AA, Brodsky KS, Aveline LD, Resing KA, Ahn NG, Gutierrez-Hartmann A. Purification and mass spectrometric identification of GA-binding protein (GABP) as the functional pituitary Ets factor binding to the basal transcription element of the prolactin promoter. J Biol Chem. 2003 May 09; 278(19):16863-72.
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Schweppe RE, Gutierrez-Hartmann A. Pituitary Ets-1 and GABP bind to the growth factor regulatory sites of the rat prolactin promoter. Nucleic Acids Res. 2001 Mar 01; 29(5):1251-60.
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Tassone F, Villard L, Clancy K, Gardiner K. Structures, sequence characteristics, and synteny relationships of the transcription factor E4TF1, the splicing factor U2AF35 and the cystathionine beta synthetase genes from Fugu rubripes. Gene. 1999 Jan 21; 226(2):211-23.
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Sucharov C, Basu A, Carter RS, Avadhani NG. A novel transcriptional initiator activity of the GABP factor binding ets sequence repeat from the murine cytochrome c oxidase Vb gene. Gene Expr. 1995; 5(2):93-111.
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