 Complement C5b
"Complement C5b" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields COMPLEMENT C5A and C5b (beta chain + alpha' chain, the residual alpha chain, bound by disulfide bond). C5b remains bound to the membrane and initiates the spontaneous assembly of the late complement components to form C5b-8-poly-C9, the MEMBRANE ATTACK COMPLEX.
| Descriptor ID |
D050776
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| MeSH Number(s) |
D12.776.124.486.274.450.625
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| Concept/Terms |
Complement C5b- Complement C5b
- C5b, Complement
- Complement 5b
- Complement Component 5b
- Component 5b, Complement
- C5b Complement
- Complement, C5b
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Below are MeSH descriptors whose meaning is more general than "Complement C5b".
Below are MeSH descriptors whose meaning is more specific than "Complement C5b".
This graph shows the total number of publications written about "Complement C5b" by people in this website by year, and whether "Complement C5b" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement C5b" by people in Profiles.
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Thurman JM, Wong M, Renner B, Frazer-Abel A, Giclas PC, Joy MS, Jalal D, Radeva MK, Gassman J, Gipson DS, Kaskel F, Friedman A, Trachtman H. Complement Activation in Patients with Focal Segmental Glomerulosclerosis. PLoS One. 2015; 10(9):e0136558.
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Cataland SR, Holers VM, Geyer S, Yang S, Wu HM. Biomarkers of terminal complement activation confirm the diagnosis of aHUS and differentiate aHUS from TTP. Blood. 2014 Jun 12; 123(24):3733-8.
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