Protein Tyrosine Phosphatase, Non-Receptor Type 1
"Protein Tyrosine Phosphatase, Non-Receptor Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
| Descriptor ID |
D054562
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| MeSH Number(s) |
D08.811.277.352.650.775.300.100 D12.644.360.585.100 D12.776.476.564.100
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| Concept/Terms |
Protein Tyrosine Phosphatase, Non-Receptor Type 1- Protein Tyrosine Phosphatase, Non-Receptor Type 1
- Protein Tyrosine Phosphatase, Non Receptor Type 1
- PTPase HA2
- Protein Tyrosine Phosphatase 1B
- PTPase 1B
- Protein-Tyrosine Phosphatase HA2
- Protein Tyrosine Phosphatase HA2
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Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 1".
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 1".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 1" by people in this website by year, and whether "Protein Tyrosine Phosphatase, Non-Receptor Type 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2004 | 0 | 5 | 5 | | 2006 | 0 | 4 | 4 | | 2007 | 0 | 1 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 1 | 1 | 2 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 1 | 2 | | 2018 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 | | 2022 | 0 | 1 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 1" by people in Profiles.
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Donovan G, O'Connor N, Moravek AM, Fox M, Markley AL, Foderaro T, Kralj JM, Fox JM. Disentangling Metabolite Detection from Pathway Stress Using Biosensors. ACS Synth Biol. 2025 Nov 21; 14(11):4388-4399.
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Sarkar A, Foderaro T, Kramer L, Markley AL, Lee J, Traylor MJ, Fox JM. Evolution-Guided Biosynthesis of Terpenoid Inhibitors. ACS Synth Biol. 2022 09 16; 11(9):3015-3027.
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Sarkar A, Kim EY, Jang T, Hongdusit A, Kim H, Choi JM, Fox JM. Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products. ACS Synth Biol. 2021 06 18; 10(6):1505-1519.
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Hongdusit A, Fox JM. Optogenetic Analysis of Allosteric Control in Protein Tyrosine Phosphatases. Biochemistry. 2021 02 02; 60(4):254-258.
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Hongdusit A, Zwart PH, Sankaran B, Fox JM. Minimally disruptive optical control of protein tyrosine phosphatase 1B. Nat Commun. 2020 02 07; 11(1):788.
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Hjortness MK, Riccardi L, Hongdusit A, Zwart PH, Sankaran B, De Vivo M, Fox JM. Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases. Biochemistry. 2018 11 13; 57(45):6443-6451.
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Hjortness MK, Riccardi L, Hongdusit A, Ruppe S, Zhao M, Kim EY, Zwart PH, Sankaran B, Arthanari H, Sousa MC, De Vivo M, Fox JM. Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation. Biochemistry. 2018 10 09; 57(40):5886-5896.
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Kerru N, Singh-Pillay A, Awolade P, Singh P. Current anti-diabetic agents and their molecular targets: A review. Eur J Med Chem. 2018 May 25; 152:436-488.
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Martinez-Garay I, Gil-Sanz C, Franco SJ, Espinosa A, Molnár Z, Mueller U. Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development. 2016 06 15; 143(12):2121-34.
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Kuban-Jankowska A, Sahu KK, Gorska M, Tuszynski JA, Wozniak M. Chicoric acid binds to two sites and decreases the activity of the YopH bacterial virulence factor. Oncotarget. 2016 Jan 19; 7(3):2229-38.
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