Peptidylprolyl Isomerase
"Peptidylprolyl Isomerase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the isomerization of proline residues within proteins. EC 5.2.1.8.
Descriptor ID |
D019696
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MeSH Number(s) |
D08.811.399.325.500
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Concept/Terms |
Peptidylprolyl Isomerase- Peptidylprolyl Isomerase
- Isomerase, Peptidylprolyl
- Proline Rotamase
- Rotamase, Proline
- Prolyl Isomerase
- Isomerase, Prolyl
- Proline Isomerase
- Isomerase, Proline
- Peptidyl-Prolyl cis-trans-Isomerase
- Peptidyl Prolyl cis trans Isomerase
- cis-trans-Isomerase, Peptidyl-Prolyl
- PPIase
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Below are MeSH descriptors whose meaning is more general than "Peptidylprolyl Isomerase".
Below are MeSH descriptors whose meaning is more specific than "Peptidylprolyl Isomerase".
This graph shows the total number of publications written about "Peptidylprolyl Isomerase" by people in this website by year, and whether "Peptidylprolyl Isomerase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 0 | 1 | 2007 | 1 | 0 | 1 | 2008 | 1 | 0 | 1 | 2009 | 0 | 1 | 1 | 2010 | 1 | 0 | 1 | 2016 | 1 | 0 | 1 | 2017 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 | 2020 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Peptidylprolyl Isomerase" by people in Profiles.
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Keogh RA, Zapf RL, Frey A, Marino EC, Null GG, Wiemels RE, Holzschu DL, Shaw LN, Carroll RK. Staphylococcus aureus Trigger Factor Is Involved in Biofilm Formation and Cooperates with the Chaperone PpiB. J Bacteriol. 2021 03 08; 203(7).
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Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG. Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 01 20; 109(2):241-256.e9.
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Keogh RA, Zapf RL, Trzeciak E, Null GG, Wiemels RE, Carroll RK. Novel Regulation of Alpha-Toxin and the Phenol-Soluble Modulins by Peptidyl-Prolyl cis/trans Isomerase Enzymes in Staphylococcus aureus. Toxins (Basel). 2019 06 16; 11(6).
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Rajiv C, Jackson SR, Cocklin S, Eisenmesser EZ, Davis TL. The spliceosomal proteins PPIH and PRPF4 exhibit bi-partite binding. Biochem J. 2017 10 25; 474(21):3689-3704.
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Byrne C, Henen MA, Belnou M, Cantrelle FX, Kamah A, Qi H, Giustiniani J, Chambraud B, Baulieu EE, Lippens G, Landrieu I, Jacquot Y. A ?-Turn Motif in the Steroid Hormone Receptor's Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52. Biochemistry. 2016 09 27; 55(38):5366-76.
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Steckelberg AL, Altmueller J, Dieterich C, Gehring NH. CWC22-dependent pre-mRNA splicing and eIF4A3 binding enables global deposition of exon junction complexes. Nucleic Acids Res. 2015 May 19; 43(9):4687-700.
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Sen R, Malik S, Frankland-Searby S, Uprety B, Lahudkar S, Bhaumik SR. Rrd1p, an RNA polymerase II-specific prolyl isomerase and activator of phosphoprotein phosphatase, promotes transcription independently of rapamycin response. Nucleic Acids Res. 2014 Sep; 42(15):9892-907.
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Steckelberg AL, Boehm V, Gromadzka AM, Gehring NH. CWC22 connects pre-mRNA splicing and exon junction complex assembly. Cell Rep. 2012 Sep 27; 2(3):454-61.
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Davis TL, Walker JR, Campagna-Slater V, Finerty PJ, Paramanathan R, Bernstein G, MacKenzie F, Tempel W, Ouyang H, Lee WH, Eisenmesser EZ, Dhe-Paganon S. Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases. PLoS Biol. 2010 Jul 27; 8(7):e1000439.
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Brodsky KS, McWilliams RR, Amura CR, Barry NP, Doctor RB. Liver cyst cytokines promote endothelial cell proliferation and development. Exp Biol Med (Maywood). 2009 Oct; 234(10):1155-65.
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