 V-Set Domain-Containing T-Cell Activation Inhibitor 1
"V-Set Domain-Containing T-Cell Activation Inhibitor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A B7 antigen subtype that inhibits the costimulation of T-cell activation, proliferation, cytokine production and development of cytotoxicity. The over expression of this protein in a variety of tumor cell types suggests its role in TUMOR IMMUNE EVASION.
| Descriptor ID |
D060907
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| MeSH Number(s) |
D12.776.467.150.900 D12.776.543.095.900 D23.050.301.285.900 D23.529.168.900
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| Concept/Terms |
V-Set Domain-Containing T-Cell Activation Inhibitor 1- V-Set Domain-Containing T-Cell Activation Inhibitor 1
- V Set Domain Containing T Cell Activation Inhibitor 1
- Immune Costimulatory Protein B7-H4
- Immune Costimulatory Protein B7 H4
- T-Cell Costimulatory Molecule B7x
- T Cell Costimulatory Molecule B7x
- B7H4 Immune Costimulatory Protein
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Below are MeSH descriptors whose meaning is more general than "V-Set Domain-Containing T-Cell Activation Inhibitor 1".
Below are MeSH descriptors whose meaning is more specific than "V-Set Domain-Containing T-Cell Activation Inhibitor 1".
This graph shows the total number of publications written about "V-Set Domain-Containing T-Cell Activation Inhibitor 1" by people in this website by year, and whether "V-Set Domain-Containing T-Cell Activation Inhibitor 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 | | 2007 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "V-Set Domain-Containing T-Cell Activation Inhibitor 1" by people in Profiles.
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Yee EU, Zaino RJ, Torkko KC, Shroyer KR. B7-H4 expression in Brenner tumours, a descriptive and comparative study. Histopathology. 2010 Apr; 56(5):652-4.
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Awadallah NS, Shroyer KR, Langer DA, Torkko KC, Chen YK, Bentz JS, Papkoff J, Liu W, Nash SR, Shah RJ. Detection of B7-H4 and p53 in pancreatic cancer: potential role as a cytological diagnostic adjunct. Pancreas. 2008 Mar; 36(2):200-6.
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Mugler KC, Singh M, Tringler B, Torkko KC, Liu W, Papkoff J, Shroyer KR. B7-h4 expression in a range of breast pathology: correlation with tumor T-cell infiltration. Appl Immunohistochem Mol Morphol. 2007 Dec; 15(4):363-70.
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Miyatake T, Tringler B, Liu W, Liu SH, Papkoff J, Enomoto T, Torkko KC, Dehn DL, Swisher A, Shroyer KR. B7-H4 (DD-O110) is overexpressed in high risk uterine endometrioid adenocarcinomas and inversely correlated with tumor T-cell infiltration. Gynecol Oncol. 2007 Jul; 106(1):119-27.
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Tringler B, Liu W, Corral L, Torkko KC, Enomoto T, Davidson S, Lucia MS, Heinz DE, Papkoff J, Shroyer KR. B7-H4 overexpression in ovarian tumors. Gynecol Oncol. 2006 Jan; 100(1):44-52.
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Tringler B, Zhuo S, Pilkington G, Torkko KC, Singh M, Lucia MS, Heinz DE, Papkoff J, Shroyer KR. B7-h4 is highly expressed in ductal and lobular breast cancer. Clin Cancer Res. 2005 Mar 01; 11(5):1842-8.
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