 B7-1 Antigen
"B7-1 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
| Descriptor ID |
D018122
|
| MeSH Number(s) |
D12.776.467.150.100 D12.776.543.095.100 D23.050.301.285.100 D23.529.168.100
|
| Concept/Terms |
B7-1 Antigen- B7-1 Antigen
- B7 1 Antigen
- CD80 Antigen
- CD80 Antigens
- B7-1 Ligand
- B7 1 Ligand
- Ligand, B7-1
- B7-1 Costimulatory Molecule
- B7 1 Costimulatory Molecule
- Costimulatory Molecule, B7-1
- Antigen, B7-1
- Antigen, B7 1
- B-Cell Activation Antigen
- B Cell Activation Antigen
- Antigens, CD80
|
Below are MeSH descriptors whose meaning is more general than "B7-1 Antigen".
Below are MeSH descriptors whose meaning is more specific than "B7-1 Antigen".
This graph shows the total number of publications written about "B7-1 Antigen" by people in this website by year, and whether "B7-1 Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 3 | 4 | | 1999 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2004 | 0 | 3 | 3 | | 2005 | 3 | 0 | 3 | | 2007 | 4 | 2 | 6 | | 2008 | 3 | 0 | 3 | | 2009 | 0 | 2 | 2 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 2 | 3 | | 2016 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "B7-1 Antigen" by people in Profiles.
-
Kleczko EK, Nguyen DT, Marsh KH, Bauer CD, Li AS, Monaghan MT, Berger MD, Furgeson SB, Gitomer BY, Chonchol MB, Clambey ET, Zimmerman KA, Nemenoff RA, Hopp K. Immune checkpoint activity regulates polycystic kidney disease progression. JCI Insight. 2023 06 22; 8(12).
-
Cara-Fuentes G, Venkatareddy M, Verma R, Segarra A, Cleuren AC, Mart?nez-Ramos A, Johnson RJ, Garg P. Glomerular endothelial cells and podocytes can express CD80 in patients with minimal change disease during relapse. Pediatr Nephrol. 2020 10; 35(10):1887-1896.
-
Rivard CJ, Tanabe T, Lanaspa MA, Watanabe H, Nomura S, Andres-Hernando A, Garth K, Sekijima M, Ishimoto T, Ariyoshi Y, Garcia GE, Shah J, Lennan B, Tasaki M, Pomposelli T, Shimizu A, Sachs DH, Johnson RJ, Yamada K. Upregulation of CD80 on glomerular podocytes plays an important role in development of proteinuria following pig-to-baboon xeno-renal transplantation - an experimental study. Transpl Int. 2018 10; 31(10):1164-1177.
-
Cara-Fuentes G, Lanaspa MA, Garcia GE, Banks M, Garin EH, Johnson RJ. Urinary CD80: a biomarker for a favorable response to corticosteroids in minimal change disease. Pediatr Nephrol. 2018 07; 33(7):1101-1103.
-
Li SX, Barrett BS, Guo K, Kassiotis G, Hasenkrug KJ, Dittmer U, Gibbert K, Santiago ML. Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection. Sci Rep. 2016 Feb 05; 6:20425.
-
Cara-Fuentes G, Wasserfall CH, Wang H, Johnson RJ, Garin EH. Minimal change disease: a dysregulation of the podocyte CD80-CTLA-4 axis? Pediatr Nephrol. 2014 Dec; 29(12):2333-40.
-
Cara-Fuentes G, Johnson RJ, Reiser J, Garin EH. CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance: response. Pediatr Nephrol. 2014 Aug; 29(8):1467-8.
-
Huskey J, Rivard C, Myint H, Lucia S, Smith M, Shimada M, Ishimoto T, Araya C, Garin EH, Johnson RJ. Minimal change disease in graft versus host disease: a podocyte response to the graft? Clin Nephrol. 2013 Dec; 80(6):469-73.
-
Cara-Fuentes G, Wei C, Segarra A, Ishimoto T, Rivard C, Johnson RJ, Reiser J, Garin EH. CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance. Pediatr Nephrol. 2014 Aug; 29(8):1363-71.
-
Chain JL, Martin AK, Mack DG, Maier LA, Palmer BE, Fontenot AP. Impaired function of CTLA-4 in the lungs of patients with chronic beryllium disease contributes to persistent inflammation. J Immunol. 2013 Aug 15; 191(4):1648-56.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
- Arthritis, Rheumatoid
- Cholangiopancreatography, Endoscopic Retrograde
- Pancreatic Ducts
- Receptors, Antigen, T-Cell
- T-Lymphocytes
- Endoscopy, Digestive System
- Receptors, Antigen, T-Cell, alpha-beta
- Polycystic Kidney, Autosomal Dominant
- Receptors, Complement 3d
- CD8-Positive T-Lymphocytes
_
Top Journals
Top journals in which articles about this concept have been published.
|