 Programmed Cell Death 1 Ligand 2 Protein
"Programmed Cell Death 1 Ligand 2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory B7 antigen that has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 RECEPTOR. It is closely-related to CD274 antigen; however, its expression is restricted to DENDRITIC CELLS and activated MACROPHAGES.
| Descriptor ID |
D061027
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| MeSH Number(s) |
D12.776.467.150.800 D12.776.543.095.800 D23.050.301.285.800 D23.529.168.800
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| Concept/Terms |
Programmed Cell Death 1 Ligand 2 Protein- Programmed Cell Death 1 Ligand 2 Protein
- CD273 Antigen
- Antigen, CD273
- PD-L2 Ligand
- Ligand, PD-L2
- PD L2 Ligand
- B7-DC Ligand
- B7 DC Ligand
- Ligand, B7-DC
- Antigens, CD273
- CD273 Antigens
- B7-DC Antigen
- Antigen, B7-DC
- B7 DC Antigen
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Below are MeSH descriptors whose meaning is more general than "Programmed Cell Death 1 Ligand 2 Protein".
Below are MeSH descriptors whose meaning is more specific than "Programmed Cell Death 1 Ligand 2 Protein".
This graph shows the total number of publications written about "Programmed Cell Death 1 Ligand 2 Protein" by people in this website by year, and whether "Programmed Cell Death 1 Ligand 2 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 3 | 3 | | 2008 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Programmed Cell Death 1 Ligand 2 Protein" by people in Profiles.
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Jones D, Como CN, Jing L, Blackmon A, Neff CP, Krueger O, Bubak AN, Palmer BE, Koelle DM, Nagel MA. Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8+ T cell effector function. PLoS Pathog. 2019 03; 15(3):e1007650.
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McKay JT, Haro MA, Daly CA, Yammani RD, Pang B, Swords WE, Haas KM. PD-L2 Regulates B-1 Cell Antibody Production against Phosphorylcholine through an IL-5-Dependent Mechanism. J Immunol. 2017 09 15; 199(6):2020-2029.
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Woods DM, Sodr? AL, Villagra A, Sarnaik A, Sotomayor EM, Weber J. HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade. Cancer Immunol Res. 2015 Dec; 3(12):1375-85.
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McKay JT, Egan RP, Yammani RD, Chen L, Shin T, Yagita H, Haas KM. PD-1 suppresses protective immunity to Streptococcus pneumoniae through a B cell-intrinsic mechanism. J Immunol. 2015 Mar 01; 194(5):2289-99.
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Radhakrishnan S, Cabrera R, Schenk EL, Nava-Parada P, Bell MP, Van Keulen VP, Marler RJ, Felts SJ, Pease LR. Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo. J Immunol. 2008 Sep 01; 181(5):3137-47.
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Heckman KL, Schenk EL, Radhakrishnan S, Pavelko KD, Hansen MJ, Pease LR. Fast-tracked CTL: rapid induction of potent anti-tumor killer T cells in situ. Eur J Immunol. 2007 Jul; 37(7):1827-35.
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Golden-Mason L, Palmer B, Klarquist J, Mengshol JA, Castelblanco N, Rosen HR. Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction. J Virol. 2007 Sep; 81(17):9249-58.
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Goldberg MV, Maris CH, Hipkiss EL, Flies AS, Zhen L, Tuder RM, Grosso JF, Harris TJ, Getnet D, Whartenby KA, Brockstedt DG, Dubensky TW, Chen L, Pardoll DM, Drake CG. Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells. Blood. 2007 Jul 01; 110(1):186-92.
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Shin T, Yoshimura K, Shin T, Crafton EB, Tsuchiya H, Housseau F, Koseki H, Schulick RD, Chen L, Pardoll DM. In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. J Exp Med. 2005 May 16; 201(10):1531-41.
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Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, Shalabi A, Shin T, Pardoll DM, Tsuchiya H. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med. 2001 Apr 02; 193(7):839-46.
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