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Rowan Mae Karvas

TitleAssistant Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-OB/GYN RS GENERAL OPS

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kumar D, Karvas RM, Jones BR, McColl ER, Diveley E, Sukanta J, Surendra S, Kelly JC, Theunissen TW, Mysorekar IU. SARS-CoV-2 ORF3a Protein Impairs Syncytiotrophoblast Maturation, Alters ZO-1 Localization, and Shifts Autophagic Pathways in Trophoblast Cells and 3D Organoids. bioRxiv. 2024 Sep 25. PMID: 39386577.
      View in: PubMed
    2. Guo M, Wu J, Chen C, Wang X, Gong A, Guan W, Karvas RM, Wang K, Min M, Wang Y, Theunissen TW, Gao S, Silva JCR. Self-renewing human na?ve pluripotent stem cells dedifferentiate in 3D culture and form blastoids spontaneously. Nat Commun. 2024 Jan 22; 15(1):668. PMID: 38253551.
      View in: PubMed
    3. Karvas RM, Theunissen TW. Generation of 3D Trophoblast Organoids from Human Na?ve Pluripotent Stem Cells. Methods Mol Biol. 2024; 2767:85-103. PMID: 37402094.
      View in: PubMed
    4. Karvas RM, Zemke JE, Ali SS, Upton E, Sane E, Fischer LA, Dong C, Park KM, Wang F, Park K, Hao S, Chew B, Meyer B, Zhou C, Dietmann S, Theunissen TW. 3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages. Cell Stem Cell. 2023 09 07; 30(9):1148-1165.e7. PMID: 37683602.
      View in: PubMed
    5. Zhou J, Tian Y, Qu Y, Williams M, Yuan Y, Karvas RM, Sheridan MA, Schulz LC, Ezashi T, Roberts MR, Schust DJ. The immune checkpoint molecule, VTCN1/B7-H4, guides differentiation and suppresses proinflammatory responses and MHC class I expression in an embryonic stem cell-derived model of human trophoblast. Front Endocrinol (Lausanne). 2023; 14:1069395. PMID: 37008954.
      View in: PubMed
    6. Karvas RM, David L, Theunissen TW. Accessing the human?trophoblast stem cell state from pluripotent and somatic cells. Cell Mol Life Sci. 2022 Nov 25; 79(12):604. PMID: 36434136.
      View in: PubMed
    7. Dong C, Fu S, Karvas RM, Chew B, Fischer LA, Xing X, Harrison JK, Popli P, Kommagani R, Wang T, Zhang B, Theunissen TW. A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells. Nat Commun. 2022 05 10; 13(1):2548. PMID: 35538076.
      View in: PubMed
    8. Karvas RM, Khan SA, Verma S, Yin Y, Kulkarni D, Dong C, Park KM, Chew B, Sane E, Fischer LA, Kumar D, Ma L, Boon ACM, Dietmann S, Mysorekar IU, Theunissen TW. Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens. Cell Stem Cell. 2022 05 05; 29(5):810-825.e8. PMID: 35523141.
      View in: PubMed
    9. Karvas RM, McInturf S, Zhou J, Ezashi T, Schust DJ, Roberts RM, Schulz LC. Use of a human embryonic stem cell model to discover GABRP, WFDC2, VTCN1 and ACTC1 as markers of early first trimester human trophoblast. Mol Hum Reprod. 2020 06 01; 26(6):425-440. PMID: 32359161.
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    10. Karvas RM, Yang Y, Ezashi T, Schust DJ, Roberts RM, Schulz LC. ITGA1 is upregulated in response to oxygen over time in a BMP4 model of trophoblast. Mol Reprod Dev. 2018 08; 85(8-9):738-739. PMID: 30076663.
      View in: PubMed
    11. Thotala D, Karvas RM, Engelbach JA, Garbow JR, Hallahan AN, DeWees TA, Laszlo A, Hallahan DE. Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells. Oncotarget. 2015 Oct 27; 6(33):35004-22. PMID: 26413814.
      View in: PubMed
    12. Bhave SR, Dadey DY, Karvas RM, Ferraro DJ, Kotipatruni RP, Jaboin JJ, Hallahan AN, Dewees TA, Linkous AG, Hallahan DE, Thotala D. Autotaxin Inhibition with PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell Lines. Front Oncol. 2013; 3:236. PMID: 24062988.
      View in: PubMed
    13. Stark DA, Karvas RM, Siegel AL, Cornelison DD. Eph/ephrin interactions modulate muscle satellite cell motility and patterning. Development. 2011 Dec; 138(24):5279-89. PMID: 22071104.
      View in: PubMed
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