 Cdc20 Proteins
"Cdc20 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly conserved proteins that specifically bind to and activate the anaphase-promoting complex-cyclosome, promoting ubiquitination and proteolysis of cell-cycle-regulatory proteins. Cdc20 is essential for anaphase-promoting complex activity, initiation of anaphase, and cyclin proteolysis during mitosis.
| Descriptor ID |
D064199
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| MeSH Number(s) |
D08.811.464.938.750.092.998 D12.776.167.024.998
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cdc20 Proteins".
Below are MeSH descriptors whose meaning is more specific than "Cdc20 Proteins".
This graph shows the total number of publications written about "Cdc20 Proteins" by people in this website by year, and whether "Cdc20 Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cdc20 Proteins" by people in Profiles.
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Huang HC, Shi J, Orth JD, Mitchison TJ. Cell death when the SAC is out of commission. Cell Cycle. 2010 Jun 01; 9(11):2049-50.
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Huang HC, Shi J, Orth JD, Mitchison TJ. Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell. 2009 Oct 06; 16(4):347-58.
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De Antoni A, Pearson CG, Cimini D, Canman JC, Sala V, Nezi L, Mapelli M, Sironi L, Faretta M, Salmon ED, Musacchio A. The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint. Curr Biol. 2005 Feb 08; 15(3):214-25.
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O'Toole ET, Mastronarde DN, Giddings TH, Winey M, Burke DJ, McIntosh JR. Three-dimensional analysis and ultrastructural design of mitotic spindles from the cdc20 mutant of Saccharomyces cerevisiae. Mol Biol Cell. 1997 Jan; 8(1):1-11.
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