 Necrosis
"Necrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.
| Descriptor ID |
D009336
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| MeSH Number(s) |
C23.550.717 G04.146.638
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Necrosis".
Below are MeSH descriptors whose meaning is more specific than "Necrosis".
This graph shows the total number of publications written about "Necrosis" by people in this website by year, and whether "Necrosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 | | 1996 | 0 | 4 | 4 | | 1997 | 0 | 3 | 3 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 3 | 3 | | 2002 | 0 | 6 | 6 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 3 | 3 | | 2005 | 0 | 7 | 7 | | 2006 | 1 | 2 | 3 | | 2007 | 0 | 2 | 2 | | 2008 | 0 | 3 | 3 | | 2009 | 0 | 7 | 7 | | 2010 | 0 | 10 | 10 | | 2011 | 0 | 7 | 7 | | 2012 | 0 | 7 | 7 | | 2013 | 0 | 5 | 5 | | 2014 | 2 | 9 | 11 | | 2015 | 1 | 2 | 3 | | 2016 | 1 | 6 | 7 | | 2017 | 0 | 3 | 3 | | 2018 | 1 | 2 | 3 | | 2019 | 2 | 5 | 7 | | 2020 | 1 | 5 | 6 | | 2021 | 2 | 7 | 9 | | 2022 | 0 | 8 | 8 | | 2023 | 0 | 7 | 7 | | 2024 | 2 | 1 | 3 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Necrosis" by people in Profiles.
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Zhao J, Vaios E, Yang Z, Lu K, Floyd S, Yang D, Ji H, Reitman ZJ, Lafata KJ, Fecci P, Kirkpatrick JP, Wang C. Radiogenomic explainable AI with neural ordinary differential equation for identifying post-SRS brain metastasis radionecrosis. Med Phys. 2025 Apr; 52(4):2661-2674.
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Retrouvey H, Meyer MA, Ipaktchi K, Maertens A, Folchert M, Lauder A. Management of Xylazine-Induced Soft-Tissue Necrosis: A Review of 20 Cases. J Am Acad Orthop Surg. 2024 Dec 01; 32(23):e1219-e1225.
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Bartlett KE, Hall SR, Rasmussen SA, Crittenden E, Dawson CA, Albulescu LO, Laprade W, Harrison RA, Saviola AJ, Modahl CM, Jenkins TP, Wilkinson MC, Guti?rrez JM, Casewell NR. Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib. Proc Natl Acad Sci U S A. 2024 May 07; 121(19):e2315597121.
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Schiess DM, Sammer MBK, Sher AC, El-Ali AM, Onwuka EA, Huang X, Staggers KA, Nguyen HN. Impact of Focused Abdominal Ultrasound Utilization on Outcomes for Children With Midgut Volvulus. J Pediatr Surg. 2024 Jun; 59(6):1101-1107.
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Gestrich CK, Davis JL, Biederman L, John I, Alaggio R, Giovannoni I, Arnold MA, Shenoy A, Tchakarov A, Al-Ibraheemi A. ALK-Rearranged Epithelioid Mesenchymal Neoplasm: Expanding the Spectrum of Tyrosine Kinase-Altered Mesenchymal Tumors. Mod Pathol. 2023 Dec; 36(12):100334.
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Feng D, Xiang X, Guan Y, Guillot A, Lu H, Chang C, He Y, Wang H, Pan H, Ju C, Colgan SP, Tacke F, Wang XW, Kunos G, Gao B. Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models. J Clin Invest. 2023 08 01; 133(15).
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Attwell AR. Endoscopic Management of Necrotic Pancreatic Fluid Collections in the Setting of Disrupted Pancreatic Duct Syndrome: Out Like a LAMS? Dig Dis Sci. 2023 08; 68(8):3213-3215.
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Axelrad JE, Li T, Bachour SP, Nakamura TI, Shah R, Sachs MC, Chang S, Hudesman DP, Holubar SD, Lightner AL, Barnes EL, Cohen BL, Rieder F, Esen E, Remzi F, Regueiro M, Click B. Early Initiation of Antitumor Necrosis Factor Therapy Reduces Postoperative Recurrence of Crohn's Disease Following Ileocecal Resection. Inflamm Bowel Dis. 2023 06 01; 29(6):888-897.
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Cheng HS, P?rez-Cremades D, Zhuang R, Jamaiyar A, Wu W, Chen J, Tzani A, Stone L, Plutzky J, Ryan TE, Goodney PP, Creager MA, Sabatine MS, Bonaca MP, Feinberg MW. Impaired angiogenesis in diabetic critical limb ischemia is mediated by a miR-130b/INHBA signaling axis. JCI Insight. 2023 05 22; 8(10).
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Kim G, Sayer G, Ransom J, Keebler M, Katz J, Kilic A, Lindenfeld J, Egnaczyk G, Shah P, Brieke A, Walenga J, Crandall D, Farrar DJ, Sundareswaran K, Uriel N. Association of Angiopoetin-2 and TNF-a With Bleeding During Left Ventricular Assist Device Support: Analysis From the PREVENT Biorepository. ASAIO J. 2023 08 01; 69(8):742-748.
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