 Netrin-1
"Netrin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A netrin that binds the DCC RECEPTOR or UNC5 receptors, resulting respectively in axon attraction or repulsion. Its interaction with these receptors also prevents APOPTOSIS; it may function as a tumor suppressor protein.
| Descriptor ID |
D000075388
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| MeSH Number(s) |
D12.644.276.860.494.500 D12.776.467.860.494.500 D12.776.631.600.494.500 D12.776.860.300.731.500 D23.125.842.500 D23.529.850.494.500
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| Concept/Terms |
Netrin-1- Netrin-1
- Netrin 1
- Netrin-1 Protein
- Netrin 1 Protein
- Protein, Netrin-1
- NTN1 Protein
- Protein, NTN1
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Below are MeSH descriptors whose meaning is more general than "Netrin-1".
Below are MeSH descriptors whose meaning is more specific than "Netrin-1".
This graph shows the total number of publications written about "Netrin-1" by people in this website by year, and whether "Netrin-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2013 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Netrin-1" by people in Profiles.
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Griffin BR, Faubel S, Edelstein CL. Biomarkers of Drug-Induced Kidney Toxicity. Ther Drug Monit. 2019 04; 41(2):213-226.
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Junge HJ, Yung AR, Goodrich LV, Chen Z. Netrin1/DCC signaling promotes neuronal migration in the dorsal spinal cord. Neural Dev. 2016 10 26; 11(1):19.
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Tak E, Ridyard D, Badulak A, Giebler A, Shabeka U, Werner T, Clambey E, Moldovan R, Zimmerman MA, Eltzschig HK, Grenz A. Protective role for netrin-1 during diabetic nephropathy. J Mol Med (Berl). 2013 Sep; 91(9):1071-80.
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Aherne CM, Collins CB, Masterson JC, Tizzano M, Boyle TA, Westrich JA, Parnes JA, Furuta GT, Rivera-Nieves J, Eltzschig HK. Neuronal guidance molecule netrin-1 attenuates inflammatory cell trafficking during acute experimental colitis. Gut. 2012 May; 61(5):695-705.
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Grenz A, Dalton JH, Bauerle JD, Badulak A, Ridyard D, Gandjeva A, Aherne CM, Brodsky KS, Kim JH, Tuder RM, Eltzschig HK. Partial netrin-1 deficiency aggravates acute kidney injury. PLoS One. 2011; 6(5):e14812.
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Tsai HH, Macklin WB, Miller RH. Distinct modes of migration position oligodendrocyte precursors for localized cell division in the developing spinal cord. J Neurosci Res. 2009 Nov 15; 87(15):3320-30.
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Schwarting GA, Wierman ME, Tobet SA. Gonadotropin-releasing hormone neuronal migration. Semin Reprod Med. 2007 Sep; 25(5):305-12.
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Tsai HH, Macklin WB, Miller RH. Netrin-1 is required for the normal development of spinal cord oligodendrocytes. J Neurosci. 2006 Feb 15; 26(7):1913-22.
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Kappler J, Franken S, Junghans U, Hoffmann R, Linke T, M?ller HW, Koch KW. Glycosaminoglycan-binding properties and secondary structure of the C-terminus of netrin-1. Biochem Biophys Res Commun. 2000 May 10; 271(2):287-91.
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