 Mitogen-Activated Protein Kinase 9
"Mitogen-Activated Protein Kinase 9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 48 and 54 KD exist due to multiple ALTERNATIVE SPLICING.
| Descriptor ID |
D048056
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.374.750 D12.644.360.450.340.750 D12.776.476.450.340.750
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| Concept/Terms |
Mitogen-Activated Protein Kinase 9- Mitogen-Activated Protein Kinase 9
- Mitogen Activated Protein Kinase 9
- Stress-Activated Protein Kinase JNK2
- Stress Activated Protein Kinase JNK2
- JNK2 Kinase
- c-jun Kinase-2
- Kinase-2, c-jun
- c jun Kinase 2
- MAPK9 Mitogen-Activated Protein Kinase
- MAPK9 Mitogen Activated Protein Kinase
- c-jun N-terminal Kinase 2
- c jun N terminal Kinase 2
- JNK2 Stress-Activated Protein Kinase
- JNK2 Stress Activated Protein Kinase
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Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 9".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 9".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 9" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 9" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2001 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2010 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 9" by people in Profiles.
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Keleher MR, Erickson K, Smith HA, Kechris KJ, Yang IV, Dabelea D, Friedman JE, Boyle KE, Jansson T. Placental Insulin/IGF-1 Signaling, PGC-1a, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4-6 Years of Age: The ECHO Healthy Start Cohort. Diabetes. 2021 03; 70(3):745-751.
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Nelson KJ, Bolduc JA, Wu H, Collins JA, Burke EA, Reisz JA, Klomsiri C, Wood ST, Yammani RR, Poole LB, Furdui CM, Loeser RF. H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes. J Biol Chem. 2018 10 19; 293(42):16376-16389.
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Joetham A, Schedel M, Takeda K, Jia Y, Ashino S, Dakhama A, Lluis A, Okamoto M, Gelfand EW. JNK2 regulates the functional plasticity of naturally occurring T regulatory cells and the enhancement of lung allergic responses. J Immunol. 2014 Sep 01; 193(5):2238-47.
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Nitta RT, Del Vecchio CA, Chu AH, Mitra SS, Godwin AK, Wong AJ. The role of the c-Jun N-terminal kinase 2-a-isoform in non-small cell lung carcinoma tumorigenesis. Oncogene. 2011 Jan 13; 30(2):234-44.
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Chen P, O'Neal JF, Ebelt ND, Cantrell MA, Mitra S, Nasrazadani A, Vandenbroek TL, Heasley LE, Van Den Berg CL. Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model. PLoS One. 2010 May 03; 5(5):e10443.
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Tyagi A, Sharma Y, Agarwal C, Agarwal R. Silibinin impairs constitutively active TGFalpha-EGFR autocrine loop in advanced human prostate carcinoma cells. Pharm Res. 2008 Sep; 25(9):2143-50.
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Dreskin SC, Thomas GW, Dale SN, Heasley LE. Isoforms of Jun kinase are differentially expressed and activated in human monocyte/macrophage (THP-1) cells. J Immunol. 2001 May 01; 166(9):5646-53.
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Das M, Bouchey DM, Moore MJ, Hopkins DC, Nemenoff RA, Stenmark KR. Hypoxia-induced proliferative response of vascular adventitial fibroblasts is dependent on g protein-mediated activation of mitogen-activated protein kinases. J Biol Chem. 2001 May 11; 276(19):15631-40.
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Wojtaszek PA, Heasley LE, Berl T. In vivo regulation of MAP kinases in Ratus norvegicus renal papilla by water loading and restriction. J Clin Invest. 1998 Nov 15; 102(10):1874-81.
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Butterfield L, Storey B, Maas L, Heasley LE. c-Jun NH2-terminal kinase regulation of the apoptotic response of small cell lung cancer cells to ultraviolet radiation. J Biol Chem. 1997 Apr 11; 272(15):10110-6.
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