 Sex-Determining Region Y Protein
"Sex-Determining Region Y Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that plays an essential role in the development of the TESTES. It is encoded by a gene on the Y chromosome and contains a specific HMG-BOX DOMAIN that is found within members of the SOX family of transcription factors.
| Descriptor ID |
D051876
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| MeSH Number(s) |
D12.776.260.719.049 D12.776.660.235.400.750.049 D12.776.664.235.400.750.049 D12.776.930.823.049
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| Concept/Terms |
Sex-Determining Region Y Protein- Sex-Determining Region Y Protein
- Sex Determining Region Y Protein
- Testis-Determining Factor
- Testis Determining Factor
- SRY Sex-Determining Region Protein
- SRY Sex Determining Region Protein
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Below are MeSH descriptors whose meaning is more general than "Sex-Determining Region Y Protein".
Below are MeSH descriptors whose meaning is more specific than "Sex-Determining Region Y Protein".
This graph shows the total number of publications written about "Sex-Determining Region Y Protein" by people in this website by year, and whether "Sex-Determining Region Y Protein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sex-Determining Region Y Protein" by people in Profiles.
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Weaver J, Rove KO, Meenakshi-Sundaram B, Vricella GJ. Genetic Testing Proves Crucial in Case of Ambiguous Genitalia and Renal Masses. Urology. 2019 Jul; 129:194-196.
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Yamauchi Y, Riel JM, Ruthig VA, Ortega EA, Mitchell MJ, Ward MA. Two genes substitute for the mouse Y chromosome for spermatogenesis and reproduction. Science. 2016 Jan 29; 351(6272):514-6.
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Vernet N, Mahadevaiah SK, Ojarikre OA, Longepied G, Prosser HM, Bradley A, Mitchell MJ, Burgoyne PS. The Y-encoded gene zfy2 acts to remove cells with unpaired chromosomes at the first meiotic metaphase in male mice. Curr Biol. 2011 May 10; 21(9):787-93.
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Delbridge ML, Longepied G, Depetris D, Mattei MG, Disteche CM, Marshall Graves JA, Mitchell MJ. TSPY, the candidate gonadoblastoma gene on the human Y chromosome, has a widely expressed homologue on the X - implications for Y chromosome evolution. Chromosome Res. 2004; 12(4):345-56.
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Mazeyrat S, Mitchell MJ. Rodent Y chromosome TSPY gene is functional in rat and non-functional in mouse. Hum Mol Genet. 1998 Mar; 7(3):557-62.
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Balaeff A, Churchill ME, Schulten K. Structure prediction of a complex between the chromosomal protein HMG-D and DNA. Proteins. 1998 Feb 01; 30(2):113-35.
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Tiersch TR, Mitchell MJ, Wachtel SS. Studies on the phylogenetic conservation of the SRY gene. Hum Genet. 1991 Sep; 87(5):571-3.
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