 Nodal Protein
"Nodal Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The founding member of the nodal signaling ligand family of proteins. Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. It is expressed asymmetrically on the left side in chordates and plays a critical role in the genesis of left-right asymmetry during vertebrate development.
| Descriptor ID |
D055457
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| MeSH Number(s) |
D12.644.276.954.550.650 D12.776.467.942.550.650 D23.529.942.550.650
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nodal Protein".
Below are MeSH descriptors whose meaning is more specific than "Nodal Protein".
This graph shows the total number of publications written about "Nodal Protein" by people in this website by year, and whether "Nodal Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nodal Protein" by people in Profiles.
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Kim SW, Yoon SJ, Chuong E, Oyolu C, Wills AE, Gupta R, Baker J. Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs. Dev Biol. 2011 Sep 15; 357(2):492-504.
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Zhang C, Klymkowsky MW. Unexpected functional redundancy between Twist and Slug (Snail2) and their feedback regulation of NF-kappaB via Nodal and Cerberus. Dev Biol. 2009 Jul 15; 331(2):340-9.
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Zhang C, Klymkowsky MW. The Sox axis, Nodal signaling, and germ layer specification. Differentiation. 2007 Jul; 75(6):536-45.
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Zhang C, Basta T, Fawcett SR, Klymkowsky MW. SOX7 is an immediate-early target of VegT and regulates Nodal-related gene expression in Xenopus. Dev Biol. 2005 Feb 15; 278(2):526-41.
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Zhang C, Basta T, Hernandez-Lagunas L, Simpson P, Stemple DL, Artinger KB, Klymkowsky MW. Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish. Dev Biol. 2004 Sep 01; 273(1):23-37.
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