 Nodal Signaling Ligands
"Nodal Signaling Ligands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Members of the transforming growth factor superfamily that play a role in pattern formation and differentiation during the pregastrulation and GASTRULATION stages of chordate development. Several nodal signaling ligands are specifically involved in the genesis of left-right asymmetry during development. The protein group is named after a critical region of the vertebrate embryo PRIMITIVE STREAK referred to as HENSEN'S NODE.
| Descriptor ID |
D055456
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| MeSH Number(s) |
D12.644.276.954.550 D12.776.467.942.550 D23.529.942.550
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nodal Signaling Ligands".
Below are MeSH descriptors whose meaning is more specific than "Nodal Signaling Ligands".
This graph shows the total number of publications written about "Nodal Signaling Ligands" by people in this website by year, and whether "Nodal Signaling Ligands" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nodal Signaling Ligands" by people in Profiles.
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Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF. Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. Elife. 2017 11 09; 6.
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Doll CA, Burkart JT, Hope KD, Halpern ME, Gamse JT. Subnuclear development of the zebrafish habenular nuclei requires ER translocon function. Dev Biol. 2011 Dec 01; 360(1):44-57.
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Zhang C, Klymkowsky MW. The Sox axis, Nodal signaling, and germ layer specification. Differentiation. 2007 Jul; 75(6):536-45.
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Zhang C, Basta T, Hernandez-Lagunas L, Simpson P, Stemple DL, Artinger KB, Klymkowsky MW. Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish. Dev Biol. 2004 Sep 01; 273(1):23-37.
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Zhang C, Basta T, Jensen ED, Klymkowsky MW. The beta-catenin/VegT-regulated early zygotic gene Xnr5 is a direct target of SOX3 regulation. Development. 2003 Dec; 130(23):5609-24.
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