 CD59 Antigens
"CD59 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)
| Descriptor ID |
D018957
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| MeSH Number(s) |
D12.776.395.550.448.140 D12.776.543.484.500.140 D12.776.543.550.418.140
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| Concept/Terms |
CD59 Antigens- CD59 Antigens
- Antigens, CD59
- Membrane Attack Complex Inhibition Factor
- Protectin
- MACIF
- Membrane Inhibitor of Reactive Lysis
- Homologous Restriction Factor 20
- CD59 Antigen
- HRF20
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Below are MeSH descriptors whose meaning is more general than "CD59 Antigens".
Below are MeSH descriptors whose meaning is more specific than "CD59 Antigens".
This graph shows the total number of publications written about "CD59 Antigens" by people in this website by year, and whether "CD59 Antigens" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 1996 | 2 | 0 | 2 | | 2003 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 3 | 1 | 4 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD59 Antigens" by people in Profiles.
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Faria B, Gaya da Costa M, Lima C, Willems L, Brandwijk R, Berger SP, Daha MR, Pestana M, Seelen MA, Poppelaars F. Soluble CD59 in peritoneal dialysis: a potential biomarker for peritoneal membrane function. J Nephrol. 2021 06; 34(3):801-810.
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Davis EM, Kim J, Menasche BL, Sheppard J, Liu X, Tan AC, Shen J. Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins. Cell Rep. 2015 Jun 23; 11(11):1727-36.
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Asavapanumas N, Ratelade J, Papadopoulos MC, Bennett JL, Levin MH, Verkman AS. Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G. J Neuroinflammation. 2014 Jan 27; 11:16.
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Wang Q, Rozelle AL, Lepus CM, Scanzello CR, Song JJ, Larsen DM, Crish JF, Bebek G, Ritter SY, Lindstrom TM, Hwang I, Wong HH, Punzi L, Encarnacion A, Shamloo M, Goodman SB, Wyss-Coray T, Goldring SR, Banda NK, Thurman JM, Gobezie R, Crow MK, Holers VM, Lee DM, Robinson WH. Identification of a central role for complement in osteoarthritis. Nat Med. 2011 Nov 06; 17(12):1674-9.
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Thurman JM, Renner B, Kunchithapautham K, Holers VM, Rohrer B. Aseptic injury to epithelial cells alters cell surface complement regulation in a tissue specific fashion. Adv Exp Med Biol. 2010; 664:151-8.
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Keysar SB, Fox MH. EMS mutant spectra generated by multi-parameter flow cytometry. Mutat Res. 2009 Dec 01; 671(1-2):6-12.
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Keysar SB, Fox MH. Kinetics of CHO A L mutant expression after treatment with gamma radiation, EMS, and asbestos. Cytometry A. 2009 May; 75(5):412-9.
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Thurman JM, Renner B, Kunchithapautham K, Ferreira VP, Pangburn MK, Ablonczy Z, Tomlinson S, Holers VM, Rohrer B. Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury. J Biol Chem. 2009 Jun 19; 284(25):16939-16947.
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Stahel PF, Flierl MA, Morgan BP, Persigehl I, Stoll C, Conrad C, Touban BM, Smith WR, Beauchamp K, Schmidt OI, Ertel W, Leinhase I. Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice. J Neuroinflammation. 2009 Jan 08; 6:2.
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Ross CD, French CT, Keysar SB, Fox MH. Mutant spectra of irradiated CHO AL cells determined with multiple markers analyzed by flow cytometry. Mutat Res. 2007 Nov 01; 624(1-2):61-70.
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