 Ephrin-A1
"Ephrin-A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
| Descriptor ID |
D036382
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| MeSH Number(s) |
D12.644.276.500.100 D12.776.395.550.448.300 D12.776.467.500.100 D12.776.543.287.100 D12.776.543.484.500.300 D12.776.543.550.418.300 D23.529.500.100
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| Concept/Terms |
Ephrin-A1- Ephrin-A1
- Ephrin A1
- Eck Ligand
- Ligand, Eck
- LERK-1 Protein
- LERK 1 Protein
- Endothelium Secreted Protein B61
- Epl1 Protein
- EPLG1
- B61 Secreted Protein, Endothelium
- Eck RPTK Ligand
- RPTK Ligand, Eck
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Below are MeSH descriptors whose meaning is more general than "Ephrin-A1".
Below are MeSH descriptors whose meaning is more specific than "Ephrin-A1".
This graph shows the total number of publications written about "Ephrin-A1" by people in this website by year, and whether "Ephrin-A1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ephrin-A1" by people in Profiles.
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Park BH, Shin MH, Douglas IS, Chung KS, Song JH, Kim SY, Kim EY, Jung JY, Kang YA, Chang J, Kim YS, Park MS. Erythropoietin-Producing Hepatoma Receptor Tyrosine Kinase A2 Modulation Associates with Protective Effect of Prone Position in Ventilator-induced Lung Injury. Am J Respir Cell Mol Biol. 2018 04; 58(4):519-529.
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Leem AY, Shin MH, Douglas IS, Song JH, Chung KS, Kim EY, Jung JY, Kang YA, Chang J, Kim YS, Park MS. All-trans retinoic acid attenuates bleomycin-induced pulmonary fibrosis via downregulating EphA2-EphrinA1 signaling. Biochem Biophys Res Commun. 2017 09 23; 491(3):721-726.
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Hong JY, Shin MH, Douglas IS, Chung KS, Kim EY, Jung JY, Kang YA, Kim SK, Chang J, Kim YS, Park MS. Inhibition of EphA2/EphrinA1 signal attenuates lipopolysaccharide-induced lung injury. Clin Sci (Lond). 2016 11 01; 130(21):1993-2003.
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Carpenter TC, Schroeder W, Stenmark KR, Schmidt EP. Eph-A2 promotes permeability and inflammatory responses to bleomycin-induced lung injury. Am J Respir Cell Mol Biol. 2012 Jan; 46(1):40-7.
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Cercone MA, Schroeder W, Schomberg S, Carpenter TC. EphA2 receptor mediates increased vascular permeability in lung injury due to viral infection and hypoxia. Am J Physiol Lung Cell Mol Physiol. 2009 Nov; 297(5):L856-63.
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Larson J, Schomberg S, Schroeder W, Carpenter TC. Endothelial EphA receptor stimulation increases lung vascular permeability. Am J Physiol Lung Cell Mol Physiol. 2008 Sep; 295(3):L431-9.
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Bruce V, Olivieri G, Eickelberg O, Miescher GC. Functional activation of EphA5 receptor does not promote cell proliferation in the aberrant EphA5 expressing human glioblastoma U-118 MG cell line. Brain Res. 1999 Mar 06; 821(1):169-76.
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