 Alkaloids
"Alkaloids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Descriptor ID |
D000470
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| MeSH Number(s) |
D03.132
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Alkaloids".
Below are MeSH descriptors whose meaning is more specific than "Alkaloids".
This graph shows the total number of publications written about "Alkaloids" by people in this website by year, and whether "Alkaloids" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 3 | 3 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 3 | 3 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 2 | 4 | | 2006 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 0 | 2 | 2 | | 2015 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Alkaloids" by people in Profiles.
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Giannotti G, Canazza I, Caffino L, Bilel S, Ossato A, Fumagalli F, Marti M. The Cathinones MDPV and a-PVP Elicit Different Behavioral and Molecular Effects Following Acute Exposure. Neurotox Res. 2017 Nov; 32(4):594-602.
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Hamilton LR, Schachter SC, Myers TM. Time Course, Behavioral Safety, and Protective Efficacy of Centrally Active Reversible Acetylcholinesterase Inhibitors in Cynomolgus Macaques. Neurochem Res. 2017 Jul; 42(7):1962-1971.
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Mohan V, Agarwal R, Singh RP. A novel alkaloid, evodiamine causes nuclear localization of cytochrome-c and induces apoptosis independent of p53 in human lung cancer cells. Biochem Biophys Res Commun. 2016 09 02; 477(4):1065-1071.
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Miller KE, Wright AJ, Olesen MK, Hovey MT, Scheerer JR. Stereoselective synthesis of (+)-loline alkaloid skeleton. J Org Chem. 2015 Feb 06; 80(3):1569-76.
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Arora I, Kashyap VK, Singh AK, Dasgupta A, Kumar B, Shaw AK. Design, synthesis and biological evaluation of bicyclic iminosugar hybrids: conformational constraint as an effective tool for tailoring the selectivity of a-glucosidase inhibitors. Org Biomol Chem. 2014 Sep 21; 12(35):6855-68.
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Marks MJ, Grady SR, Salminen O, Paley MA, Wageman CR, McIntosh JM, Whiteaker P. a6?2*-subtype nicotinic acetylcholine receptors are more sensitive than a4?2*-subtype receptors to regulation by chronic nicotine administration. J Neurochem. 2014 Jul; 130(2):185-98.
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Sala M, Braida D, Pucci L, Manfredi I, Marks MJ, Wageman CR, Grady SR, Loi B, Fucile S, Fasoli F, Zoli M, Tasso B, Sparatore F, Clementi F, Gotti C. CC4, a dimer of cytisine, is a selective partial agonist at a4?2/a6?2 nAChR with improved selectivity for tobacco smoking cessation. Br J Pharmacol. 2013 Feb; 168(4):835-49.
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Papke RL, Wecker L, Stitzel JA. Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. J Pharmacol Exp Ther. 2010 May; 333(2):501-18.
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LaBarbera DV, Modzelewska K, Glazar AI, Gray PD, Kaur M, Liu T, Grossman D, Harper MK, Kuwada SK, Moghal N, Ireland CM. The marine alkaloid naamidine A promotes caspase-dependent apoptosis in tumor cells. Anticancer Drugs. 2009 Jul; 20(6):425-36.
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Marks MJ, Meinerz NM, Drago J, Collins AC. Gene targeting demonstrates that alpha4 nicotinic acetylcholine receptor subunits contribute to expression of diverse [3H]epibatidine binding sites and components of biphasic 86Rb+ efflux with high and low sensitivity to stimulation by acetylcholine. Neuropharmacology. 2007 Sep; 53(3):390-405.
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