Cross-Priming
"Cross-Priming" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Class I-restricted activation of CD8-POSITIVE LYMPHOCYTES resulting from ANTIGEN PRESENTATION of exogenous ANTIGENS (cross-presentation). This is in contrast to normal activation of these lymphocytes (direct-priming) which results from presentation of endogenous antigens.
Descriptor ID |
D045142
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MeSH Number(s) |
G12.450.050.400.545.150 G12.565.150
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cross-Priming".
Below are MeSH descriptors whose meaning is more specific than "Cross-Priming".
This graph shows the total number of publications written about "Cross-Priming" by people in this website by year, and whether "Cross-Priming" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 1 | 2 | 2007 | 1 | 1 | 2 | 2008 | 2 | 1 | 3 | 2010 | 2 | 0 | 2 | 2011 | 1 | 0 | 1 | 2013 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cross-Priming" by people in Profiles.
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Rawat K, Jakubzick CV. Channeling antigens to CD8+ T cells. Science. 2023 06 23; 380(6651):1218-1219.
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Watchmaker PB, Lahl K, Lee M, Baumjohann D, Morton J, Kim SJ, Zeng R, Dent A, Ansel KM, Diamond B, Hadeiba H, Butcher EC. Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice. Nat Immunol. 2014 Jan; 15(1):98-108.
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Engels B, Engelhard VH, Sidney J, Sette A, Binder DC, Liu RB, Kranz DM, Meredith SC, Rowley DA, Schreiber H. Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity. Cancer Cell. 2013 Apr 15; 23(4):516-26.
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Li Y, Hahn T, Garrison K, Cui ZH, Thorburn A, Thorburn J, Hu HM, Akporiaye ET. The vitamin E analogue a-TEA stimulates tumor autophagy and enhances antigen cross-presentation. Cancer Res. 2012 Jul 15; 72(14):3535-45.
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Oh JZ, Kurche JS, Burchill MA, Kedl RM. TLR7 enables cross-presentation by multiple dendritic cell subsets through a type I IFN-dependent pathway. Blood. 2011 Sep 15; 118(11):3028-38.
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Baker K, Qiao SW, Kuo TT, Aveson VG, Platzer B, Andersen JT, Sandlie I, Chen Z, de Haar C, Lencer WI, Fiebiger E, Blumberg RS. Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells. Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24):9927-32.
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Oh JZ, Kedl RM. The capacity to induce cross-presentation dictates the success of a TLR7 agonist-conjugate vaccine for eliciting cellular immunity. J Immunol. 2010 Oct 15; 185(8):4602-8.
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Takamura S, Roberts AD, Jelley-Gibbs DM, Wittmer ST, Kohlmeier JE, Woodland DL. The route of priming influences the ability of respiratory virus-specific memory CD8+ T cells to be activated by residual antigen. J Exp Med. 2010 Jun 07; 207(6):1153-60.
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Pang S, Zhang L, Wang H, Yi Z, Li L, Gao L, Zhao J, Tisch R, Katz JD, Wang B. CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice. Eur J Immunol. 2009 Oct; 39(10):2716-24.
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Moldenhauer LM, Diener KR, Thring DM, Brown MP, Hayball JD, Robertson SA. Cross-presentation of male seminal fluid antigens elicits T cell activation to initiate the female immune response to pregnancy. J Immunol. 2009 Jun 15; 182(12):8080-93.
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