 X-Linked Inhibitor of Apoptosis Protein
"X-Linked Inhibitor of Apoptosis Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitor of apoptosis protein that is translated by a rare cap-independent mechanism. It blocks caspase-mediated cellular destruction by inhibiting CASPASE 3; CASPASE 7; and CASPASE 9.
| Descriptor ID |
D051636
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| MeSH Number(s) |
D08.811.464.938.750.210.750 D12.644.360.075.437.750 D12.776.476.075.437.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "X-Linked Inhibitor of Apoptosis Protein".
Below are MeSH descriptors whose meaning is more specific than "X-Linked Inhibitor of Apoptosis Protein".
This graph shows the total number of publications written about "X-Linked Inhibitor of Apoptosis Protein" by people in this website by year, and whether "X-Linked Inhibitor of Apoptosis Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2003 | 0 | 1 | 1 | | 2004 | 0 | 2 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 1 | 2 | | 2010 | 1 | 1 | 2 |
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Below are the most recent publications written about "X-Linked Inhibitor of Apoptosis Protein" by people in Profiles.
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Milanovic D, Pe?ic V, Popic J, Tanic N, Kanazir S, Jevtovic-Todorovic V, Ru?dijic S. Propofol anesthesia induces proapoptotic tumor necrosis factor-a and pro-nerve growth factor signaling and prosurvival Akt and XIAP expression in neonatal rat brain. J Neurosci Res. 2014 Oct; 92(10):1362-73.
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Arroyo JA, Li C, Schlabritz-Loutsevitch N, McDonald T, Nathanielsz P, Galan HL. Increased placental XIAP and caspase 3 is associated with increased placental apoptosis in a baboon model of maternal nutrient reduction. Am J Obstet Gynecol. 2010 Oct; 203(4):364.e13-8.
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Zhang L, Kavanagh BD, Thorburn AM, Camidge DR. Preclinical and clinical estimates of the basal apoptotic rate of a cancer predict the amount of apoptosis induced by subsequent proapoptotic stimuli. Clin Cancer Res. 2010 Sep 01; 16(17):4478-89.
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Cao L, Petrusca DN, Satpathy M, Nakshatri H, Petrache I, Matei D. Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling. Carcinogenesis. 2008 Oct; 29(10):1893-900.
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Arroyo JA, Anthony RV, Galan HL. Decreased placental X-linked inhibitor of apoptosis protein in an ovine model of intrauterine growth restriction. Am J Obstet Gynecol. 2008 Jul; 199(1):80.e1-8.
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Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Chen Y, Yuasa T, Tanaka K, Narushima M, Miki A, Misawa H, Tabata Y, Jun HS, Matsumoto S, Fox IJ, Tanaka N, Kobayashi N. Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice. Diabetes. 2007 May; 56(5):1259-67.
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Ravi R, Fuchs EJ, Jain A, Pham V, Yoshimura K, Prouser T, Jalla S, Zhou X, Garrett-Mayer E, Kaufmann SH, Schulick RD, Pardoll DM, Bedi A. Resistance of cancers to immunologic cytotoxicity and adoptive immunotherapy via X-linked inhibitor of apoptosis protein expression and coexisting defects in mitochondrial death signaling. Cancer Res. 2006 Feb 01; 66(3):1730-9.
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Ravi R, Jain AJ, Schulick RD, Pham V, Prouser TS, Allen H, Mayer EG, Yu H, Pardoll DM, Ashkenazi A, Bedi A. Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL. Cancer Res. 2004 Dec 15; 64(24):9105-14.
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Gardai SJ, Whitlock BB, Xiao YQ, Bratton DB, Henson PM. Oxidants inhibit ERK/MAPK and prevent its ability to delay neutrophil apoptosis downstream of mitochondrial changes and at the level of XIAP. J Biol Chem. 2004 Oct 22; 279(43):44695-703.
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Gardai SJ, Hoontrakoon R, Goddard CD, Day BJ, Chang LY, Henson PM, Bratton DL. Oxidant-mediated mitochondrial injury in eosinophil apoptosis: enhancement by glucocorticoids and inhibition by granulocyte-macrophage colony-stimulating factor. J Immunol. 2003 Jan 01; 170(1):556-66.
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