Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Jingshi Shen

TitleAssociate Professor
InstitutionUniversity of Colorado Boulder
DepartmentBiology-MCD Instruction
Phone303/492-6166

    Collapse Research 
    Collapse research activities and funding
    K99DK080080     (SHEN, JINGSHI)Sep 20, 2007 - Aug 31, 2009
    NIH/NIDDK
    Regulation of GLUT4 Exocytosis
    Role: Principal Investigator

    R00DK080080     (SHEN, JINGSHI)Feb 15, 2009 - Jan 31, 2012
    NIH/NIDDK
    Regulation of GLUT4 Exocytosis
    Role: Principal Investigator

    R56DK095367     (SHEN, JINGSHI)Sep 21, 2012 - Mar 31, 2013
    NIH/NIDDK
    Regulatory Mechanisms of GLUT4 Exocytosis
    Role: Principal Investigator

    R01GM102217     (SHEN, JINGSHI)Apr 1, 2013 - Jan 31, 2018
    NIH/NIGMS
    Protein-Membrane Interactions in Regulated Exocytosis
    Role: Principal Investigator

    R01DK095367     (SHEN, JINGSHI)Apr 1, 2013 - Mar 31, 2018
    NIH/NIDDK
    Regulatory Mechanisms of GLUT4 Exocytosis
    Role: Principal Investigator

    R21AI128443     (LI, SUZHAO)Aug 14, 2017 - Jul 31, 2019
    NIH/NIAID
    Molecular Mechanisms of Cytokine Induced Insulin Resistance
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Gulbranson DR, Davis EM, Demmitt BA, Ouyang Y, Ye Y, Yu H, Shen J. RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis. Proc Natl Acad Sci U S A. 2017 Sep 26; 114(39):E8224-E8233. PMID: 28894007.
      View in: PubMed
    2. Yu H, Liu Y, Gulbranson DR, Paine A, Rathore SS, Shen J. Extended synaptotagmins are Ca2+-dependent lipid transfer proteins at membrane contact sites. Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16):4362-7. PMID: 27044075; PMCID: PMC4843466 [Available on 10/19/16].
    3. Yu H, Rathore SS, Shen C, Liu Y, Ouyang Y, Stowell MH, Shen J. Reconstituting Intracellular Vesicle Fusion Reactions: The Essential Role of Macromolecular Crowding. J Am Chem Soc. 2015 Oct 14; 137(40):12873-83. PMID: 26431309; PMCID: PMC4638180.
    4. Davis EM, Kim J, Menasche BL, Sheppard J, Liu X, Tan AC, Shen J. Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins. Cell Rep. 2015 Jun 23; 11(11):1727-36. PMID: 26074080; PMCID: PMC4481156.
    5. Zhang C, Lee S, Peng Y, Bunker E, Shen C, Giaime E, Shen J, Shen J, Zhou Z, Liu X. A chemical genetic approach to probe the function of PINK1 in regulating mitochondrial dynamics. Cell Res. 2015 Mar; 25(3):394-7. PMID: 25475060; PMCID: PMC4349247.
    6. Yu H, Rathore SS, Gulbranson DR, Shen J. The N- and C-terminal domains of tomosyn play distinct roles in soluble N-ethylmaleimide-sensitive factor attachment protein receptor binding and fusion regulation. J Biol Chem. 2014 Sep 12; 289(37):25571-80. PMID: 25063806; PMCID: PMC4162162.
    7. Yu H, Rathore SS, Lopez JA, Davis EM, James DE, Martin JL, Shen J. Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins. Proc Natl Acad Sci U S A. 2013 Aug 27; 110(35):E3271-80. PMID: 23918365; PMCID: PMC3761595.
    8. Yu H, Rathore SS, Shen J. Synip arrests soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE)-dependent membrane fusion as a selective target membrane SNARE-binding inhibitor. J Biol Chem. 2013 Jun 28; 288(26):18885-93. PMID: 23665562; PMCID: PMC3696664.
    9. Yu H, Rathore SS, Davis EM, Ouyang Y, Shen J. Doc2b promotes GLUT4 exocytosis by activating the SNARE-mediated fusion reaction in a calcium- and membrane bending-dependent manner. Mol Biol Cell. 2013 Apr; 24(8):1176-84. PMID: 23427263; PMCID: PMC3623638.
    10. Rathore SS, Ghosh N, Ouyang Y, Shen J. Topological arrangement of the intracellular membrane fusion machinery. Mol Biol Cell. 2011 Jul 15; 22(14):2612-9. PMID: 21633111; PMCID: PMC3135485.
    11. Rathore SS, Bend EG, Yu H, Hammarlund M, Jorgensen EM, Shen J. Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22399-406. PMID: 21139055; PMCID: PMC3012463.
    12. Shen J, Rathore SS, Khandan L, Rothman JE. SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion. J Cell Biol. 2010 Jul 12; 190(1):55-63. PMID: 20603329; PMCID: PMC2911676.
    Shen's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _

    Copyright © 2017 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.10.0)