 Protein Structure, Secondary
"Protein Structure, Secondary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The level of protein structure in which regular hydrogen-bond interactions within contiguous stretches of polypeptide chain give rise to ALPHA-HELICES; BETA-STRANDS (which align to form BETA-SHEETS), or other types of coils. This is the first folding level of protein conformation.
| Descriptor ID |
D017433
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| MeSH Number(s) |
G02.111.570.820.709.600
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| Concept/Terms |
Protein Structure, Secondary- Protein Structure, Secondary
- Secondary Protein Structure
- Protein Structures, Secondary
- Secondary Protein Structures
- Structure, Secondary Protein
- Structures, Secondary Protein
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Below are MeSH descriptors whose meaning is more general than "Protein Structure, Secondary".
Below are MeSH descriptors whose meaning is more specific than "Protein Structure, Secondary".
This graph shows the total number of publications written about "Protein Structure, Secondary" by people in this website by year, and whether "Protein Structure, Secondary" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 1 | 2 | | 1994 | 2 | 3 | 5 | | 1995 | 1 | 0 | 1 | | 1996 | 4 | 1 | 5 | | 1997 | 4 | 4 | 8 | | 1998 | 2 | 5 | 7 | | 1999 | 0 | 12 | 12 | | 2000 | 0 | 8 | 8 | | 2001 | 0 | 12 | 12 | | 2002 | 1 | 12 | 13 | | 2003 | 0 | 7 | 7 | | 2004 | 1 | 9 | 10 | | 2005 | 1 | 15 | 16 | | 2006 | 1 | 14 | 15 | | 2007 | 0 | 15 | 15 | | 2008 | 0 | 10 | 10 | | 2009 | 2 | 9 | 11 | | 2010 | 2 | 7 | 9 | | 2011 | 1 | 13 | 14 | | 2012 | 0 | 5 | 5 | | 2013 | 1 | 11 | 12 | | 2014 | 0 | 5 | 5 | | 2015 | 0 | 10 | 10 | | 2016 | 0 | 3 | 3 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 4 | 4 | | 2019 | 1 | 3 | 4 | | 2020 | 0 | 2 | 2 | | 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Protein Structure, Secondary" by people in Profiles.
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Borovsky D, Deckers K, Vanhove AC, Verstraete M, Rougé P, Shatters RG, Powell CA. Cloning and Characterization of Aedes aegypti Trypsin Modulating Oostatic Factor (TMOF) Gut Receptor. Biomolecules. 2021 06 23; 11(7).
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Zhao H, Young N, Kalchschmidt J, Lieberman J, El Khattabi L, Casellas R, Asturias FJ. Structure of mammalian Mediator complex reveals Tail module architecture and interaction with a conserved core. Nat Commun. 2021 03 01; 12(1):1355.
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Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG. Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 01 20; 109(2):241-256.e9.
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Delesky EA, Thomas PE, Charrier M, Cameron JC, Srubar WV. Effect of pH on the activity of ice-binding protein from Marinomonas primoryensis. Extremophiles. 2021 Jan; 25(1):1-13.
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Bandi S, Singh SM, Shah DD, Upadhyay V, Mallela KMG. 2D NMR Analysis of the Effect of Asparagine Deamidation Versus Methionine Oxidation on the Structure, Stability, Aggregation, and Function of a Therapeutic Protein. Mol Pharm. 2019 11 04; 16(11):4621-4635.
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Kendrick BS, Gabrielson JP, Solsberg CW, Ma E, Wang L. Determining Spectroscopic Quantitation Limits for Misfolded Structures. J Pharm Sci. 2020 01; 109(1):933-936.
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Pegram LM, Liddle JC, Xiao Y, Hoh M, Rudolph J, Iverson DB, Vigers GP, Smith D, Zhang H, Wang W, Moffat JG, Ahn NG. Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2. Proc Natl Acad Sci U S A. 2019 07 30; 116(31):15463-15468.
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Zhang X, Peng Y, Grace PM, Metcalf MD, Kwilasz AJ, Wang Y, Zhang T, Wu S, Selfridge BR, Portoghese PS, Rice KC, Watkins LR, Hutchinson MR, Wang X. Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling. FASEB J. 2019 08; 33(8):9577-9587.
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Shea D, Hsu CC, Bi TM, Paranjapye N, Childers MC, Cochran J, Tomberlin CP, Wang L, Paris D, Zonderman J, Varani G, Link CD, Mullan M, Daggett V. a-Sheet secondary structure in amyloid ß-peptide drives aggregation and toxicity in Alzheimer's disease. Proc Natl Acad Sci U S A. 2019 04 30; 116(18):8895-8900.
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Henen MA, Mahlawat P, Zwieb C, Kodali RB, Hinck CS, Hanna RD, Krzysiak TC, Ilangovan U, Cano KE, Hinck G, Vonberg M, McCabe M, Hinck AP. TGF-ß2 uses the concave surface of its extended finger region to bind betaglycan's ZP domain via three residues specific to TGF-ß and inhibin-a. J Biol Chem. 2019 03 01; 294(9):3065-3080.
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