 Dopamine
"Dopamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
| Descriptor ID |
D004298
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| MeSH Number(s) |
D02.092.211.215.311.342 D02.092.311.342
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| Concept/Terms |
Dopamine- Dopamine
- 4-(2-Aminoethyl)-1,2-benzenediol
- Hydroxytyramine
- 3,4-Dihydroxyphenethylamine
- 3,4 Dihydroxyphenethylamine
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Below are MeSH descriptors whose meaning is more general than "Dopamine".
Below are MeSH descriptors whose meaning is more specific than "Dopamine".
This graph shows the total number of publications written about "Dopamine" by people in this website by year, and whether "Dopamine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 1 | 1 | 2 | | 1997 | 0 | 1 | 1 | | 1998 | 2 | 0 | 2 | | 1999 | 1 | 0 | 1 | | 2000 | 3 | 3 | 6 | | 2001 | 2 | 4 | 6 | | 2002 | 6 | 4 | 10 | | 2003 | 7 | 4 | 11 | | 2004 | 4 | 0 | 4 | | 2005 | 3 | 4 | 7 | | 2006 | 5 | 3 | 8 | | 2007 | 4 | 3 | 7 | | 2008 | 9 | 4 | 13 | | 2009 | 9 | 7 | 16 | | 2010 | 3 | 1 | 4 | | 2011 | 9 | 4 | 13 | | 2012 | 7 | 6 | 13 | | 2013 | 8 | 10 | 18 | | 2014 | 7 | 5 | 12 | | 2015 | 4 | 5 | 9 | | 2016 | 9 | 1 | 10 | | 2017 | 6 | 5 | 11 | | 2018 | 12 | 4 | 16 | | 2019 | 5 | 3 | 8 | | 2020 | 5 | 2 | 7 | | 2021 | 3 | 1 | 4 | | 2022 | 5 | 5 | 10 | | 2023 | 2 | 2 | 4 | | 2024 | 6 | 3 | 9 | | 2025 | 2 | 1 | 3 |
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Below are the most recent publications written about "Dopamine" by people in Profiles.
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Yee AG, Liao Y, Muntean BS, Ford CP. Discrete spatiotemporal encoding of striatal dopamine transmission. Science. 2025 Jul 10; 389(6756):200-206.
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Hohorst AA, Tanner MK, Han R, Korth KM, Westerman JD, Mendoza CS, Dryden MQ, Alvarez LA, Abdul RA, Loetz EC, Oleson EB, Greenwood BN. High ovarian hormones present during fear extinction reduce fear relapse through a nigrostriatal dopamine pathway. Biol Sex Differ. 2025 Jun 01; 16(1):38.
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Teichman EM, Hu J, Lin HY, Fisher-Foye RL, Blando A, Hu X, Kaniskan H?, Montgomery SE, Cai M, Parise LF, Wang J, Russo SJ, Han MH, Jin J, Morel C. Design and validation of novel brain-penetrant HCN channel inhibitors to ameliorate social stress-induced susceptible phenotype. Mol Psychiatry. 2025 Sep; 30(9):3937-3950.
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Nielsen BE, Ford CP. Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA-induced dyskinetic behaviors. Sci Adv. 2024 Nov 22; 10(47):eadp6301.
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Gordi?n-V?lez WJ, Browne KD, Galarraga JH, Chouhan D, Duda JE, Espa?a RA, Chen HI, Burdick JA, Cullen DK. Dopaminergic Axon Tracts Within a Hyaluronic Acid Hydrogel Encasement to Restore the Nigrostriatal Pathway. Adv Healthc Mater. 2025 Jan; 14(2):e2402997.
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Ryan MB, Girasole AE, Flores AJ, Twedell EL, McGregor MM, Brakaj R, Paletzki RF, Hnasko TS, Gerfen CR, Nelson AB. Excessive firing of dyskinesia-associated striatal direct pathway neurons is gated by dopamine and excitatory synaptic input. Cell Rep. 2024 08 27; 43(8):114483.
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Bergum N, Berezin CT, Vigh J. Dopamine enhances GABAA receptor-mediated current amplitude in a subset of intrinsically photosensitive retinal ganglion cells. J Neurophysiol. 2024 08 01; 132(2):501-513.
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Labouesse MA, Wilhelm M, Kagiampaki Z, Yee AG, Denis R, Harada M, Gresch A, Marinescu AM, Otomo K, Curreli S, Serratosa Capdevila L, Zhou X, Cola RB, Ravotto L, Gl?ck C, Cherepanov S, Weber B, Zhou X, Katner J, Svensson KA, Fellin T, Trudeau LE, Ford CP, Sych Y, Patriarchi T. A chemogenetic approach for dopamine imaging with tunable sensitivity. Nat Commun. 2024 Jul 02; 15(1):5551.
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Tanner MK, Hohorst AA, Westerman JD, Mendoza CS, Han R, Moya NA, Jaime J, Alvarez LM, Dryden MQ, Balolia A, Abdul RA, Loetz EC, Greenwood BN. Pharmacological manipulations of the dorsomedial and dorsolateral striatum during fear extinction reveal opposing roles in fear renewal. Neurobiol Learn Mem. 2024 07; 212:107937.
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Williams BM, Steed ND, Woolley JT, Moedl AA, Nelson CA, Jones GC, Burris MD, Arias HR, Kim OH, Jang EY, Hone AJ, McIntosh JM, Yorgason JT, Steffensen SC. Catharanthine Modulates Mesolimbic Dopamine Transmission and Nicotine Psychomotor Effects via Inhibition of a6-Nicotinic Receptors and Dopamine Transporters. ACS Chem Neurosci. 2024 05 01; 15(9):1738-1754.
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