 Lupus Erythematosus, Systemic
"Lupus Erythematosus, Systemic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Descriptor ID |
D008180
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| MeSH Number(s) |
C17.300.480 C20.111.590
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lupus Erythematosus, Systemic".
Below are MeSH descriptors whose meaning is more specific than "Lupus Erythematosus, Systemic".
This graph shows the total number of publications written about "Lupus Erythematosus, Systemic" by people in this website by year, and whether "Lupus Erythematosus, Systemic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 1 | 2 | 3 | | 2001 | 3 | 2 | 5 | | 2002 | 3 | 2 | 5 | | 2003 | 4 | 1 | 5 | | 2004 | 6 | 3 | 9 | | 2005 | 5 | 0 | 5 | | 2006 | 5 | 1 | 6 | | 2007 | 4 | 1 | 5 | | 2008 | 6 | 0 | 6 | | 2009 | 6 | 1 | 7 | | 2010 | 7 | 2 | 9 | | 2011 | 5 | 2 | 7 | | 2012 | 7 | 0 | 7 | | 2013 | 6 | 2 | 8 | | 2014 | 5 | 2 | 7 | | 2015 | 3 | 1 | 4 | | 2016 | 5 | 2 | 7 | | 2017 | 2 | 1 | 3 | | 2018 | 5 | 2 | 7 | | 2019 | 8 | 1 | 9 | | 2020 | 6 | 0 | 6 | | 2021 | 6 | 3 | 9 | | 2022 | 10 | 0 | 10 | | 2023 | 9 | 0 | 9 | | 2024 | 2 | 1 | 3 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Lupus Erythematosus, Systemic" by people in Profiles.
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Shmizu M, Kaneko S, Shimbo A, Hatano M, Miyaoka F, Irabu H, Akutsu Y, Hayashi Y, Akamine K, Mori M. Anifrolumab for refractory cutaneous lupus lesions in pediatric systemic lupus erythematosus. Lupus. 2025 Apr; 34(5):533-536.
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Sadun RE, Cooper JC, Belot A, Avcin T, Aggarwal A, Ainsworth J, Akinsete A, Ardoin SP, Beresford MW, Bortey L, Brunner HI, Chang JC, Ciurtin C, Daftary A, Eberhard B, Feldman CH, Hedrich CM, Hersh AO, Hiraki LT, Isenberg DA, Kamphuis S, Knight AM, Lambert L, Levy DM, Marks SD, Maxwell N, Migowa A, Moore K, Ozen S, Ramsey-Goldman R, Ravelli A, Reeve BB, Rubinstein TB, Saad-Magalhaes C, Sawhney S, Schanberg LE, von Scheven E, Scott C, Son MB, Tony G, Weitzman ER, Wenderfer SE, Woodside A, Lewandowski LB, Smith EM. Development of CARRA/PReS-endorsed consensus Core and Expanded Datasets in childhood-onset systemic lupus erythematosus for international registry-based research. Ann Rheum Dis. 2025 Feb; 84(2):158-168.
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Gonzalez NM, Zou D, Zeng Z, Feng FX, Zhang X, Sannes C, Gu A, Zu Y, Chen W. Transient Anti-TCR? mAb Treatment Induces CD4 + T Cell Exhaustion and Prolongs Survival in a Mouse Model of Systemic Lupus Erythematosus. Immunology. 2025 02; 174(2):239-246.
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Mills TS, Kain B, Burchill MA, Danis E, Lucas ED, Culp-Hill R, Cowan CM, Schleicher WE, Patel SB, Tran BT, Cao R, Goodspeed A, Ferrara S, Bevers S, Jir?n Tamburini BA, Roede JR, D'Alessandro A, King KY, Pietras EM. A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune mice. Cell Stem Cell. 2024 Nov 07; 31(11):1630-1649.e8.
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Winters R, Grubb A, Eldermire R, McGuinn E, Altman N, Cornwell WK. Eosinophilic Myocarditis in a Patient With Systemic Lupus Erythematosus and P-Neutrophil Cytoplasmic Antibodies Associated Vasculitis Overlap. Circ Heart Fail. 2024 Sep; 17(9):e011612.
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Kammeyer R, Ogbu EA, Cooper JC, Stolz E, Piquet AL, Fuhlbrigge RC, Bennett JL, Hutaff-Lee C. Cognitive dysfunction in pediatric systemic lupus erythematosus: current knowledge and future directions. Child Neuropsychol. 2024 07; 30(5):818-846.
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Baxter RM, Wang CS, Garcia-Perez JE, Kong DS, Coleman BM, Larchenko V, Schuyler RP, Jackson C, Ghosh T, Rudra P, Paul D, Claassen M, Rochford R, Cambier JC, Ghosh D, Cooper JC, Smith MJ, Hsieh EWY. Expansion of extrafollicular B and T cell subsets in childhood-onset systemic lupus erythematosus. Front Immunol. 2023; 14:1208282.
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Chau K, Raksadawan Y, Allison K, Ice JA, Scofield RH, Chepelev I, Harley ITW. Pervasive Sharing of Causal Genetic Risk Factors Contributes to Clinical and Molecular Overlap between Sj?gren's Disease and Systemic Lupus Erythematosus. Int J Mol Sci. 2023 Sep 22; 24(19).
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Narazaki H, Akioka S, Akutsu Y, Araki M, Fujieda M, Fukuhara D, Hara R, Hashimoto K, Hattori S, Hayashibe R, Imagawa T, Inoue Y, Ishida H, Ito S, Itoh Y, Kawabe T, Kitoh T, Kobayashi I, Matsubayashi T, Miyamae T, Mizuta M, Mori M, Murase A, Nakagishi Y, Nagatani K, Nakano N, Nishimura T, Nozawa T, Okamoto N, Okura Y, Sawada H, Sawanobori E, Sugita Y, Tanabe Y, Tomiita M, Yamaguchi KI, Yasuoka R, Yokoyama K. Epidemiology conduction of paediatric rheumatic diseases based on the registry database of the Pediatric Rheumatology Association of Japan. Mod Rheumatol. 2023 Aug 25; 33(5):1021-1029.
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Cuneo BF, Buyon JP, Sammaritano L, Jaeggi E, Arya B, Behrendt N, Carvalho J, Cohen J, Cumbermack K, DeVore G, Doan T, Donofrio MT, Freud L, Galan HL, Gropler MRF, Haxel C, Hornberger LK, Howley LW, Izmirly P, Killen SS, Kaplinski M, Krishnan A, Lavasseur S, Lindblade C, Matta J, Makhoul M, Miller J, Morris S, Paul E, Perrone E, Phoon C, Pinto N, Rychik J, Satou G, Saxena A, Sklansky M, Stranic J, Strasburger JF, Srivastava S, Srinivasan S, Tacy T, Tworetzky W, Uzun O, Yagel S, Zaretsky MV, Moon-Grady AJ. Knowledge is power: regarding SMFM Consult Series #64: Systemic lupus erythematosus in pregnancy. Am J Obstet Gynecol. 2023 10; 229(4):361-363.
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