 Lupus Erythematosus, Systemic
"Lupus Erythematosus, Systemic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Descriptor ID |
D008180
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| MeSH Number(s) |
C17.300.480 C20.111.590
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lupus Erythematosus, Systemic".
Below are MeSH descriptors whose meaning is more specific than "Lupus Erythematosus, Systemic".
This graph shows the total number of publications written about "Lupus Erythematosus, Systemic" by people in this website by year, and whether "Lupus Erythematosus, Systemic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 0 | 1 | | 1992 | 3 | 1 | 4 | | 1993 | 1 | 1 | 2 | | 1994 | 2 | 1 | 3 | | 1995 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 2 | 0 | 2 | | 1998 | 2 | 0 | 2 | | 1999 | 1 | 2 | 3 | | 2001 | 4 | 1 | 5 | | 2002 | 2 | 2 | 4 | | 2003 | 3 | 3 | 6 | | 2004 | 2 | 3 | 5 | | 2005 | 6 | 0 | 6 | | 2006 | 6 | 1 | 7 | | 2007 | 6 | 1 | 7 | | 2008 | 5 | 2 | 7 | | 2009 | 8 | 0 | 8 | | 2010 | 8 | 1 | 9 | | 2011 | 10 | 3 | 13 | | 2012 | 16 | 2 | 18 | | 2013 | 14 | 3 | 17 | | 2014 | 8 | 2 | 10 | | 2015 | 7 | 1 | 8 | | 2016 | 7 | 2 | 9 | | 2017 | 2 | 1 | 3 | | 2018 | 3 | 0 | 3 |
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Below are the most recent publications written about "Lupus Erythematosus, Systemic" by people in Profiles.
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Sang A, Danhorn T, Peterson JN, Rankin AL, O'Connor BP, Leach SM, Torres RM, Pelanda R. Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus. Nat Commun. 2018 09 28; 9(1):3973.
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Kozora E, Filley CM, Erkan D, Ulug AM, Vo A, Ramon G, Burleson A, Zimmerman RD, Lockshin MD. Longitudinal evaluation of diffusion tensor imaging and cognition in systemic lupus erythematosus. Lupus. 2018 Oct; 27(11):1810-1818.
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Kim MY, Guerra MM, Kaplowitz E, Laskin CA, Petri M, Branch DW, Lockshin MD, Sammaritano LR, Merrill JT, Porter TF, Sawitzke A, Lynch AM, Buyon JP, Salmon JE. Complement activation predicts adverse pregnancy outcome in patients with systemic lupus erythematosus and/or antiphospholipid antibodies. Ann Rheum Dis. 2018 04; 77(4):549-555.
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Thurman JM, Frazer-Abel A, Holers VM. The Evolving Landscape for Complement Therapeutics in Rheumatic and Autoimmune Diseases. Arthritis Rheumatol. 2017 11; 69(11):2102-2113.
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Munroe ME, Young KA, Kamen DL, Guthridge JM, Niewold TB, Costenbader KH, Weisman MH, Ishimori ML, Wallace DJ, Gilkeson GS, Karp DR, Harley JB, Norris JM, James JA. Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features. Arthritis Rheumatol. 2017 03; 69(3):630-642.
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Rubtsova K, Rubtsov AV, Thurman JM, Mennona JM, Kappler JW, Marrack P. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. J Clin Invest. 2017 Apr 03; 127(4):1392-1404.
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Kozora E, Ulug AM, Erkan D, Vo A, Filley CM, Ramon G, Burleson A, Zimmerman R, Lockshin MD. Functional Magnetic Resonance Imaging of Working Memory and Executive Dysfunction in Systemic Lupus Erythematosus and Antiphospholipid Antibody-Positive Patients. Arthritis Care Res (Hoboken). 2016 11; 68(11):1655-1663.
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Janssen WJ, Bratton DL, Jakubzick CV, Henson PM. Myeloid Cell Turnover and Clearance. Microbiol Spectr. 2016 11; 4(6).
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Berens-Norman HM, Boackle SA. Editorial: Subduing Lupus: Can Preclinical Autoimmune Disease Be Arrested? Arthritis Rheumatol. 2016 10; 68(10):2357-60.
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Yelnik CM, Kozora E, Appenzeller S. Cognitive disorders and antiphospholipid antibodies. Autoimmun Rev. 2016 Dec; 15(12):1193-1198.
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