Purpura, Thrombocytopenic, Idiopathic
"Purpura, Thrombocytopenic, Idiopathic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
Descriptor ID |
D016553
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MeSH Number(s) |
C15.378.100.802.687.600 C15.378.140.855.925.750.600 C15.378.463.740 C20.111.759 C20.841.600 C23.550.414.950.687.600 C23.888.885.687.687.600
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Concept/Terms |
Purpura, Thrombocytopenic, Idiopathic- Purpura, Thrombocytopenic, Idiopathic
- Idiopathic Thrombocytopenic Purpura
- Idiopathic Thrombocytopenic Purpuras
- Purpura, Idiopathic Thrombocytopenic
- Purpuras, Idiopathic Thrombocytopenic
- Thrombocytopenic Purpura, Idiopathic
- Thrombocytopenic Purpuras, Idiopathic
- Immune Thrombocytopenic Purpura
- Immune Thrombocytopenic Purpuras
- Purpura, Immune Thrombocytopenic
- Purpuras, Immune Thrombocytopenic
- Thrombocytopenic Purpura, Immune
- Thrombocytopenic Purpuras, Immune
- Immune Thrombocytopenia
- Immune Thrombocytopenias
- Thrombocytopenia, Immune
- Thrombocytopenias, Immune
- Thrombocytopenic Purpura, Autoimmune
- Werlhof Disease
- Disease, Werlhof
- Werlhof's Disease
- Disease, Werlhof's
- Werlhofs Disease
- Autoimmune Thrombocytopenia
- Autoimmune Thrombocytopenias
- Thrombocytopenia, Autoimmune
- Thrombocytopenias, Autoimmune
- Autoimmune Thrombocytopenic Purpura
- Autoimmune Thrombocytopenic Purpuras
- Purpura, Autoimmune Thrombocytopenic
- Purpuras, Autoimmune Thrombocytopenic
- Purpura, Thrombocytopenic, Autoimmune
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Below are MeSH descriptors whose meaning is more general than "Purpura, Thrombocytopenic, Idiopathic".
- Diseases [C]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Blood Coagulation Disorders [C15.378.100]
- Purpura [C15.378.100.802]
- Purpura, Thrombocytopenic [C15.378.100.802.687]
- Purpura, Thrombocytopenic, Idiopathic [C15.378.100.802.687.600]
- Blood Platelet Disorders [C15.378.140]
- Thrombocytopenia [C15.378.140.855]
- Thrombotic Microangiopathies [C15.378.140.855.925]
- Purpura, Thrombocytopenic [C15.378.140.855.925.750]
- Purpura, Thrombocytopenic, Idiopathic [C15.378.140.855.925.750.600]
- Hemorrhagic Disorders [C15.378.463]
- Purpura, Thrombocytopenic, Idiopathic [C15.378.463.740]
- Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]
- Purpura, Thrombocytopenic, Idiopathic [C20.111.759]
- Purpura, Thrombocytopenic [C20.841]
- Purpura, Thrombocytopenic, Idiopathic [C20.841.600]
- Pathological Conditions, Signs and Symptoms [C23]
- Pathologic Processes [C23.550]
- Hemorrhage [C23.550.414]
- Purpura [C23.550.414.950]
- Purpura, Thrombocytopenic [C23.550.414.950.687]
- Purpura, Thrombocytopenic, Idiopathic [C23.550.414.950.687.600]
- Signs and Symptoms [C23.888]
- Skin Manifestations [C23.888.885]
- Purpura [C23.888.885.687]
- Purpura, Thrombocytopenic [C23.888.885.687.687]
- Purpura, Thrombocytopenic, Idiopathic [C23.888.885.687.687.600]
Below are MeSH descriptors whose meaning is more specific than "Purpura, Thrombocytopenic, Idiopathic".
This graph shows the total number of publications written about "Purpura, Thrombocytopenic, Idiopathic" by people in this website by year, and whether "Purpura, Thrombocytopenic, Idiopathic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 | 2004 | 1 | 0 | 1 | 2008 | 1 | 0 | 1 | 2009 | 1 | 0 | 1 | 2012 | 2 | 0 | 2 | 2021 | 1 | 0 | 1 | 2022 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Purpura, Thrombocytopenic, Idiopathic" by people in Profiles.
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Abou-Ismail MY, Zhang C, Presson AP, Chaturvedi S, Antun AG, Farland AM, Woods R, Metjian A, Park YA, de Ridder G, Gibson B, Kasthuri RS, Liles DK, Akwaa F, Clover T, Baumann Kreuziger L, Sridharan M, Go RS, McCrae KR, Upreti HV, Gangaraju R, Kocher NK, Zheng XL, Raval JS, Masias C, Cataland SR, Johnson AD, Davis E, Evans MD, Mazepa M, Lim MY. A descriptive analysis of fatal outcomes in immune thrombotic thrombocytopenic purpura in the USTMA TTP Registry. Blood Adv. 2024 02 13; 8(3):620-623.
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Kanack AJ, Jones CG, Singh B, Leger RR, Splinter NP, Heikal NM, Pruthi RK, Chen D, George G, Abou-Ismail MY, Wool GD, Gundabolu K, Padmanabhan A. Off-the-shelf cryopreserved platelets for the detection of HIT and VITT antibodies. Blood. 2022 12 22; 140(25):2722-2729.
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Kanack AJ, Bayas A, George G, Abou-Ismail MY, Singh B, Kohlhagen MC, Splinter NP, Christ M, Naumann M, Moser KA, Smock KJ, Grazioli A, Wen R, Wang D, Murray DL, Padmanabhan A. Monoclonal and oligoclonal anti-platelet factor 4 antibodies mediate VITT. Blood. 2022 07 07; 140(1):73-77.
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Major A, Carll T, Chan CW, Christenson C, Aldarweesh F, Wool GD, Cohen KS. Refractory vaccine-induced immune thrombotic thrombocytopenia (VITT) managed with delayed therapeutic plasma exchange (TPE). J Clin Apher. 2022 Feb; 37(1):117-121.
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Liang Y, Rascati K, Richards K. Prevalence of primary immune thrombocytopenia and related healthcare resource utilization among Texas Medicaid beneficiaries. Curr Med Res Opin. 2021 08; 37(8):1315-1322.
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Patil AS, Dotters-Katz SK, Metjian AD, James AH, Swamy GK. Use of a thrombopoietin mimetic for chronic immune thrombocytopenic purpura in pregnancy. Obstet Gynecol. 2013 Aug; 122(2 Pt 2):483-485.
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Shores D, Kobak G, Pegram LD, Whitington PF, Shneider BL. Giant cell hepatitis and immune thrombocytopenic purpura: reversal of liver failure with rituximab therapy. J Pediatr Gastroenterol Nutr. 2012 Oct; 55(4):e128-30.
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O'Leary ST, Glanz JM, McClure DL, Akhtar A, Daley MF, Nakasato C, Baxter R, Davis RL, Izurieta HS, Lieu TA, Ball R. The risk of immune thrombocytopenic purpura after vaccination in children and adolescents. Pediatrics. 2012 Feb; 129(2):248-55.
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Prasad S, Harman R, Henderson R, Chunnilal S, Simpson D. Laparoscopic splenectomy and the treatment outcomes for idiopathic thrombocytopaenic purpura at North Shore Hospital. N Z Med J. 2009 Jun 19; 122(1297):38-48.
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Glanz J, France E, Xu S, Hayes T, Hambidge S. A population-based, multisite cohort study of the predictors of chronic idiopathic thrombocytopenic purpura in children. Pediatrics. 2008 Mar; 121(3):e506-12.
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