 Cryptochromes
"Cryptochromes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Flavoproteins that function as circadian rhythm signaling proteins in ANIMALS and as blue-light photoreceptors in PLANTS. They are structurally-related to DNA PHOTOLYASES and it is believed that both classes of proteins may have originated from an earlier protein that played a role in protecting primitive organisms from the cyclical exposure to UV LIGHT.
| Descriptor ID |
D056931
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| MeSH Number(s) |
D12.644.128.150 D12.776.189.250 D12.776.331.180 D12.776.765.593.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cryptochromes".
Below are MeSH descriptors whose meaning is more specific than "Cryptochromes".
This graph shows the total number of publications written about "Cryptochromes" by people in this website by year, and whether "Cryptochromes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2014 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2019 | 1 | 2 | 3 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cryptochromes" by people in Profiles.
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Hernández-Candia CN, Tucker CL. Optogenetic Control of Gene Expression Using Cryptochrome 2 and a Light-Activated Degron. Methods Mol Biol. 2020; 2173:151-158.
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Meador K, Wysoczynski CL, Norris AJ, Aoto J, Bruchas MR, Tucker CL. Achieving tight control of a photoactivatable Cre recombinase gene switch: new design strategies and functional characterization in mammalian cells and rodent. Nucleic Acids Res. 2019 09 26; 47(17):e97.
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Hernández-Candia CN, Wysoczynski CL, Tucker CL. Advances in optogenetic regulation of gene expression in mammalian cells using cryptochrome 2 (CRY2). Methods. 2019 07 15; 164-165:81-90.
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Liu Q, Sinnen BL, Boxer EE, Schneider MW, Grybko MJ, Buchta WC, Gibson ES, Wysoczynski CL, Ford CP, Gottschalk A, Aoto J, Tucker CL, Kennedy MJ. A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission. Neuron. 2019 03 06; 101(5):863-875.e6.
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Pathak GP, Spiltoir JI, Höglund C, Polstein LR, Heine-Koskinen S, Gersbach CA, Rossi J, Tucker CL. Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. Nucleic Acids Res. 2017 Nov 16; 45(20):e167.
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Sinnen BL, Bowen AB, Forte JS, Hiester BG, Crosby KC, Gibson ES, Dell'Acqua ML, Kennedy MJ. Optogenetic Control of Synaptic Composition and Function. Neuron. 2017 Feb 08; 93(3):646-660.e5.
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Taslimi A, Zoltowski B, Miranda JG, Pathak GP, Hughes RM, Tucker CL. Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase. Nat Chem Biol. 2016 06; 12(6):425-30.
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Pathak GP, Strickland D, Vrana JD, Tucker CL. Benchmarking of optical dimerizer systems. ACS Synth Biol. 2014 Nov 21; 3(11):832-8.
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Tucker CL, Vrana JD, Kennedy MJ. Tools for controlling protein interactions using light. Curr Protoc Cell Biol. 2014 Sep 02; 64:17.16.1-20.
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Hughes RM, Bolger S, Tapadia H, Tucker CL. Light-mediated control of DNA transcription in yeast. Methods. 2012 Dec; 58(4):385-91.
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