 Acyl-CoA Dehydrogenase
"Acyl-CoA Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein oxidoreductase that has specificity for medium-chain fatty acids. It forms a complex with ELECTRON TRANSFERRING FLAVOPROTEINS and conveys reducing equivalents to UBIQUINONE.
| Descriptor ID |
D042964
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| MeSH Number(s) |
D08.811.682.660.150.100 D12.776.331.099
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| Concept/Terms |
Acyl-CoA Dehydrogenase- Acyl-CoA Dehydrogenase
- Acyl CoA Dehydrogenase
- Dehydrogenase, Acyl-CoA
- Fatty-acyl CoA Dehydrogenase
- CoA Dehydrogenase, Fatty-acyl
- Dehydrogenase, Fatty-acyl CoA
- Fatty acyl CoA Dehydrogenase
- MCACA-Dehydrogenase
- MCACA Dehydrogenase
- Medium Chain Acyl-CoA Dehydrogenase
- Medium Chain Acyl CoA Dehydrogenase
- Medium-Chain Acyl-Coenzyme A Dehydrogenase
- Medium Chain Acyl Coenzyme A Dehydrogenase
- Octanoyl-CoA Dehydrogenase
- Dehydrogenase, Octanoyl-CoA
- Octanoyl CoA Dehydrogenase
- Palmitoyl-CoA Dehydrogenase
- Dehydrogenase, Palmitoyl-CoA
- Palmitoyl CoA Dehydrogenase
- Acyl-coenzyme A Dehydrogenase
- Acyl coenzyme A Dehydrogenase
- Dehydrogenase, Acyl-coenzyme A
- Medium-Chain Acyl-CoA Dehydrogenase
- Acyl-CoA Dehydrogenase, Medium-Chain
- Dehydrogenase, Medium-Chain Acyl-CoA
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Below are MeSH descriptors whose meaning is more general than "Acyl-CoA Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Acyl-CoA Dehydrogenase".
This graph shows the total number of publications written about "Acyl-CoA Dehydrogenase" by people in this website by year, and whether "Acyl-CoA Dehydrogenase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Acyl-CoA Dehydrogenase" by people in Profiles.
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van Rijt WJ, Jager EA, Allersma DP, Aktuglu Zeybek A?, Bhattacharya K, Debray FG, Ellaway CJ, Gautschi M, Geraghty MT, Gil-Ortega D, Larson AA, Moore F, Morava E, Morris AA, Oishi K, Schiff M, Scholl-B?rgi S, Tchan MC, Vockley J, Witters P, Wortmann SB, van Spronsen F, Van Hove JLK, Derks TGJ. Efficacy and safety of D,L-3-hydroxybutyrate (D,L-3-HB) treatment in multiple acyl-CoA dehydrogenase deficiency. Genet Med. 2020 05; 22(5):908-916.
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Voskuil MI. Mycobacterium tuberculosis cholesterol catabolism requires a new class of acyl coenzyme A dehydrogenase. J Bacteriol. 2013 Oct; 195(19):4319-21.
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McCandless SE, Chandrasekar R, Linard S, Kikano S, Rice L. Sequencing from dried blood spots in infants with "false positive" newborn screen for MCAD deficiency. Mol Genet Metab. 2013 Jan; 108(1):51-5.
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Van Hove JL, Myers S, Kerckhove KV, Freehauf C, Bernstein L. Acute nutrition management in the prevention of metabolic illness: a practical approach with glucose polymers. Mol Genet Metab. 2009 May; 97(1):1-3.
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O'Reilly L, Bross P, Corydon TJ, Olpin SE, Hansen J, Kenney JM, McCandless SE, Frazier DM, Winter V, Gregersen N, Engel PC, Andresen BS. The Y42H mutation in medium-chain acyl-CoA dehydrogenase, which is prevalent in babies identified by MS/MS-based newborn screening, is temperature sensitive. Eur J Biochem. 2004 Oct; 271(20):4053-63.
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Van Hove JL, Gr?newald S, Jaeken J, Demaerel P, Declercq PE, Bourdoux P, Niezen-Koning K, Deanfeld JE, Leonard JV. D,L-3-hydroxybutyrate treatment of multiple acyl-CoA dehydrogenase deficiency (MADD). Lancet. 2003 Apr 26; 361(9367):1433-5.
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Nguyen TV, Riggs C, Babovic-Vuksanovic D, Kim YS, Carpenter JF, Burghardt TP, Gregersen N, Vockley J. Purification and characterization of two polymorphic variants of short chain acyl-CoA dehydrogenase reveal reduction of catalytic activity and stability of the Gly185Ser enzyme. Biochemistry. 2002 Sep 17; 41(37):11126-33.
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Chisholm CA, Vavelidis F, Lovell MA, Sweetman L, Roe CR, Roe DS, Frerman FE, Wilson WG. Prenatal diagnosis of multiple acyl-CoA dehydrogenase deficiency: association with elevated alpha-fetoprotein and cystic renal changes. Prenat Diagn. 2001 Oct; 21(10):856-9.
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Andresen BS, Dobrowolski SF, O'Reilly L, Muenzer J, McCandless SE, Frazier DM, Udvari S, Bross P, Knudsen I, Banas R, Chace DH, Engel P, Naylor EW, Gregersen N. Medium-chain acyl-CoA dehydrogenase (MCAD) mutations identified by MS/MS-based prospective screening of newborns differ from those observed in patients with clinical symptoms: identification and characterization of a new, prevalent mutation that results in mild MCAD deficiency. Am J Hum Genet. 2001 Jun; 68(6):1408-18.
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Rinaldo P, O'Shea JJ, Goodman SI, Miller LV, Fennessey PV, Whelan DT, Hill RE, Tanaka K. Comparison of urinary acylglycines and acylcarnitines as diagnostic markers of medium-chain acyl-CoA dehydrogenase deficiency. J Inherit Metab Dis. 1989; 12 Suppl 2:325-8.
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