 Gene Products, tat
"Gene Products, tat" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Trans-acting transcription factors produced by retroviruses such as HIV. They are nuclear proteins whose expression is required for viral replication. The tat protein stimulates LONG TERMINAL REPEAT-driven RNA synthesis for both viral regulatory and viral structural proteins. tat stands for trans-activation of transcription.
| Descriptor ID |
D015696
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| MeSH Number(s) |
D12.776.260.755.199 D12.776.930.900.199 D12.776.964.925.984.400
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| Concept/Terms |
Gene Products, tat- Gene Products, tat
- tat Gene Products
- tat Protein
- Gene Product, tat
- tat Gene Product
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Below are MeSH descriptors whose meaning is more general than "Gene Products, tat".
Below are MeSH descriptors whose meaning is more specific than "Gene Products, tat".
This graph shows the total number of publications written about "Gene Products, tat" by people in this website by year, and whether "Gene Products, tat" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 1 | 2 | | 1992 | 0 | 1 | 1 | | 1996 | 1 | 1 | 2 | | 2002 | 2 | 1 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gene Products, tat" by people in Profiles.
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Klesmith JR, Bacik JP, Wrenbeck EE, Michalczyk R, Whitehead TA. Trade-offs between enzyme fitness and solubility illuminated by deep mutational scanning. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):2265-2270.
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Cota-Gomez A, Flores AC, Ling XF, Varella-Garcia M, Flores SC. HIV-1 Tat increases oxidant burden in the lungs of transgenic mice. Free Radic Biol Med. 2011 Nov 01; 51(9):1697-707.
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Vest RS, O'Leary H, Coultrap SJ, Kindy MS, Bayer KU. Effective post-insult neuroprotection by a novel Ca(2+)/ calmodulin-dependent protein kinase II (CaMKII) inhibitor. J Biol Chem. 2010 Jul 02; 285(27):20675-82.
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Cittelly DM, Nesic O, Johnson K, Hulsebosch C, Perez-Polo JR. Detrimental effects of antiapoptotic treatments in spinal cord injury. Exp Neurol. 2008 Apr; 210(2):295-307.
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Bullok KE, Gammon ST, Violini S, Prantner AM, Villalobos VM, Sharma V, Piwnica-Worms D. Permeation peptide conjugates for in vivo molecular imaging applications. Mol Imaging. 2006 Jan-Mar; 5(1):1-15.
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Porntadavity S, Nath A, Prachayasittikul V, Cota-Gomez A, Flores SC, St Clair DK. Different roles of Sp family members in HIV-1 Tat-mediated manganese superoxide dismutase suppression in hepatocellular carcinoma cells. DNA Cell Biol. 2005 May; 24(5):299-310.
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Marecki JC, Cota-Gomez A, Vaitaitis GM, Honda JR, Porntadavity S, St Clair DK, Flores SC. HIV-1 Tat regulates the SOD2 basal promoter by altering Sp1/Sp3 binding activity. Free Radic Biol Med. 2004 Sep 15; 37(6):869-80.
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Gammon ST, Villalobos VM, Prior JL, Sharma V, Piwnica-Worms D. Quantitative analysis of permeation peptide complexes labeled with Technetium-99m: chiral and sequence-specific effects on net cell uptake. Bioconjug Chem. 2003 Mar-Apr; 14(2):368-76.
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Comerford KM, Leonard MO, Karhausen J, Carey R, Colgan SP, Taylor CT. Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia. Proc Natl Acad Sci U S A. 2003 Feb 04; 100(3):986-91.
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Bai J, Banda N, Lee NS, Rossi J, Akkina R. RNA-based anti-HIV-1 gene therapeutic constructs in SCID-hu mouse model. Mol Ther. 2002 Dec; 6(6):770-82.
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