 Transforming Growth Factor beta3
"Transforming Growth Factor beta3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
| Descriptor ID |
D053782
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| MeSH Number(s) |
D12.644.276.374.687.300 D12.644.276.954.775.300 D12.776.467.374.687.300 D12.776.467.942.775.300 D23.529.942.775.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta3".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta3".
This graph shows the total number of publications written about "Transforming Growth Factor beta3" by people in this website by year, and whether "Transforming Growth Factor beta3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2019 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transforming Growth Factor beta3" by people in Profiles.
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Martin AR, Patel JM, Locke RC, Eby MR, Saleh KS, Davidson MD, Sennett ML, Zlotnick HM, Chang AH, Carey JL, Burdick JA, Mauck RL. Nanofibrous hyaluronic acid scaffolds delivering TGF-?3 and SDF-1a for articular cartilage repair in a large animal model. Acta Biomater. 2021 05; 126:170-182.
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Schneider MC, Chu S, Randolph MA, Bryant SJ. An in vitro and in vivo comparison of cartilage growth in chondrocyte-laden matrix metalloproteinase-sensitive poly(ethylene glycol) hydrogels with localized transforming growth factor ?3. Acta Biomater. 2019 07 15; 93:97-110.
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Beck EC, Barragan M, Tadros MH, Kiyotake EA, Acosta FM, Kieweg SL, Detamore MS. Chondroinductive Hydrogel Pastes Composed of Naturally Derived Devitalized Cartilage. Ann Biomed Eng. 2016 06; 44(6):1863-80.
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Kim IL, Pfeifer CG, Fisher MB, Saxena V, Meloni GR, Kwon MY, Kim M, Steinberg DR, Mauck RL, Burdick JA. Fibrous Scaffolds with Varied Fiber Chemistry and Growth Factor Delivery Promote Repair in a Porcine Cartilage Defect Model. Tissue Eng Part A. 2015 Nov; 21(21-22):2680-90.
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Fornetti J, Flanders KC, Henson PM, Tan AC, Borges VF, Schedin P. Mammary epithelial cell phagocytosis downstream of TGF-?3 is characterized by adherens junction reorganization. Cell Death Differ. 2016 Feb; 23(2):185-96.
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Illien-J?nger S, Lu Y, Purmessur D, Mayer JE, Walter BA, Roughley PJ, Qureshi SA, Hecht AC, Iatridis JC. Detrimental effects of discectomy on intervertebral disc biology can be decelerated by growth factor treatment during surgery: a large animal organ culture model. Spine J. 2014 Nov 01; 14(11):2724-32.
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Bian L, Guvendiren M, Mauck RL, Burdick JA. Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis. Proc Natl Acad Sci U S A. 2013 Jun 18; 110(25):10117-22.
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Bian L, Zhai DY, Tous E, Rai R, Mauck RL, Burdick JA. Enhanced MSC chondrogenesis following delivery of TGF-?3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo. Biomaterials. 2011 Sep; 32(27):6425-34.
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Norris RA, Potts JD, Yost MJ, Junor L, Brooks T, Tan H, Hoffman S, Hart MM, Kern MJ, Damon B, Markwald RR, Goodwin RL. Periostin promotes a fibroblastic lineage pathway in atrioventricular valve progenitor cells. Dev Dyn. 2009 May; 238(5):1052-63.
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Eslami A, Gallant-Behm CL, Hart DA, Wiebe C, Honardoust D, Gardner H, H?kkinen L, Larjava HS. Expression of integrin alphavbeta6 and TGF-beta in scarless vs scar-forming wound healing. J Histochem Cytochem. 2009 Jun; 57(6):543-57.
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