 Aminoimidazole Carboxamide
"Aminoimidazole Carboxamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases.
| Descriptor ID |
D000620
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| MeSH Number(s) |
D03.383.129.308.030
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aminoimidazole Carboxamide".
Below are MeSH descriptors whose meaning is more specific than "Aminoimidazole Carboxamide".
This graph shows the total number of publications written about "Aminoimidazole Carboxamide" by people in this website by year, and whether "Aminoimidazole Carboxamide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 2 | 3 | | 2015 | 2 | 1 | 3 | | 2017 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aminoimidazole Carboxamide" by people in Profiles.
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Lane SL, Houck JA, Doyle AS, Bales ES, Lorca RA, Julian CG, Moore LG. AMP-activated protein kinase activator AICAR attenuates hypoxia-induced murine fetal growth restriction in part by improving uterine artery blood flow. J Physiol. 2020 09; 598(18):4093-4105.
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Lee DM, Sevits KJ, Battson ML, Wei Y, Cox-York KA, Gentile CL. Monounsaturated fatty acids protect against palmitate-induced lipoapoptosis in human umbilical vein endothelial cells. PLoS One. 2019; 14(12):e0226940.
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Miao Z, Adamiak RW, Antczak M, Batey RT, Becka AJ, Biesiada M, Boniecki MJ, Bujnicki JM, Chen SJ, Cheng CY, Chou FC, Ferr?-D'Amar? AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Lach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B, Xiao Y, Xu X, Zhang D, Zok T, Westhof E. RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme. RNA. 2017 05; 23(5):655-672.
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Ruehle MD, Kieft JS. Molecular prejudice: RNA discrimination against purines allows response to a cellular alarm. Nat Struct Mol Biol. 2015 Oct; 22(10):754-6.
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Trausch JJ, Marcano-Vel?zquez JG, Matyjasik MM, Batey RT. Metal Ion-Mediated Nucleobase Recognition by the ZTP Riboswitch. Chem Biol. 2015 Jul 23; 22(7):829-37.
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Idrovo JP, Yang WL, Jacob A, Aziz M, Nicastro J, Coppa GF, Wang P. AICAR attenuates organ injury and inflammatory response after intestinal ischemia and reperfusion. Mol Med. 2015 Mar 19; 20:676-83.
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Ray SP, Duval N, Wilkinson TG, Shaheen SE, Ghosh K, Patterson D. Inherent properties of adenylosuccinate lyase could explain S-Ado/SAICAr ratio due to homozygous R426H and R303C mutations. Biochim Biophys Acta. 2013 Aug; 1834(8):1545-53.
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Sandoval D, Barrera JG, Stefater MA, Sisley S, Woods SC, D'Alessio DD, Seeley RJ. The anorectic effect of GLP-1 in rats is nutrient dependent. PLoS One. 2012; 7(12):e51870.
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Lesniewski LA, Zigler MC, Durrant JR, Donato AJ, Seals DR. Sustained activation of AMPK ameliorates age-associated vascular endothelial dysfunction via a nitric oxide-independent mechanism. Mech Ageing Dev. 2012 May; 133(5):368-71.
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Idrovo JP, Yang WL, Matsuda A, Nicastro J, Coppa GF, Wang P. Post-treatment with the combination of 5-aminoimidazole-4-carboxyamide ribonucleoside and carnitine improves renal function after ischemia/reperfusion injury. Shock. 2012 Jan; 37(1):39-46.
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