TNF Receptor-Associated Death Domain Protein
"TNF Receptor-Associated Death Domain Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 34 kDa signal transducing adaptor protein that associates with TUMOR NECROSIS FACTOR RECEPTOR TYPE 1. It facilitates the recruitment of signaling proteins such as TNF RECEPTOR-ASSOCIATED FACTOR 2 and FAS ASSOCIATED DEATH DOMAIN PROTEIN to the receptor complex.
Descriptor ID |
D053199
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MeSH Number(s) |
D12.644.360.024.285.600 D12.644.360.024.500.249 D12.644.360.075.421.600 D12.776.157.057.018.600 D12.776.157.057.500.249 D12.776.476.024.320.775 D12.776.476.024.500.249 D12.776.476.075.421.600
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "TNF Receptor-Associated Death Domain Protein".
Below are MeSH descriptors whose meaning is more specific than "TNF Receptor-Associated Death Domain Protein".
This graph shows the total number of publications written about "TNF Receptor-Associated Death Domain Protein" by people in this website by year, and whether "TNF Receptor-Associated Death Domain Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "TNF Receptor-Associated Death Domain Protein" by people in Profiles.
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Pietras EM, Cheng G. A New TRADDition in intracellular antiviral signaling. Sci Signal. 2008 Jul 29; 1(30):pe36.
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Bender LM, Morgan MJ, Thomas LR, Liu ZG, Thorburn A. The adaptor protein TRADD activates distinct mechanisms of apoptosis from the nucleus and the cytoplasm. Cell Death Differ. 2005 May; 12(5):473-81.
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Soond SM, Terry JL, Colbert JD, Riches DW. TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB. Mol Cell Biol. 2003 Nov; 23(22):8334-44.
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Morgan M, Thorburn J, Pandolfi PP, Thorburn A. Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms. J Cell Biol. 2002 Jun 10; 157(6):975-84.
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