 Folic Acid
"Folic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
| Descriptor ID |
D005492
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| MeSH Number(s) |
D03.633.100.733.631.400
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| Concept/Terms |
Folic Acid- Folic Acid
- Vitamin M
- Vitamin B9
- B9, Vitamin
- Pteroylglutamic Acid
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Below are MeSH descriptors whose meaning is more general than "Folic Acid".
Below are MeSH descriptors whose meaning is more specific than "Folic Acid".
This graph shows the total number of publications written about "Folic Acid" by people in this website by year, and whether "Folic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 2 | 2 | | 1994 | 0 | 1 | 1 | | 1995 | 2 | 2 | 4 | | 1996 | 1 | 2 | 3 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 2 | 2 | | 2000 | 1 | 1 | 2 | | 2001 | 3 | 1 | 4 | | 2002 | 2 | 5 | 7 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 2 | 3 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 3 | 1 | 4 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 5 | 4 | 9 | | 2012 | 3 | 2 | 5 | | 2013 | 1 | 2 | 3 | | 2014 | 1 | 1 | 2 | | 2015 | 0 | 2 | 2 | | 2016 | 2 | 2 | 4 | | 2017 | 3 | 3 | 6 | | 2018 | 2 | 3 | 5 | | 2019 | 0 | 2 | 2 | | 2020 | 3 | 1 | 4 | | 2021 | 2 | 1 | 3 |
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Below are the most recent publications written about "Folic Acid" by people in Profiles.
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Fiddler JL, Xiu Y, Blum JE, Lamarre SG, Phinney WN, Stabler SP, Brosnan ME, Brosnan JT, Thalacker-Mercer AE, Field MS. Reduced Shmt2 Expression Impairs Mitochondrial Folate Accumulation and Respiration, and Leads to Uracil Accumulation in Mouse Mitochondrial DNA. J Nutr. 2021 10 01; 151(10):2882-2893.
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Hoffman MC, Freedman R, Law AJ, Clark AM, Hunter SK. Maternal nutrients and effects of gestational COVID-19 infection on fetal brain development. Clin Nutr ESPEN. 2021 06; 43:1-8.
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Higa R, Rosario FJ, Powell TL, Jansson T, Jawerbaum A. Inhibition of MTOR signaling impairs rat embryo organogenesis by affecting folate availability. Reproduction. 2021 04; 161(4):365-373.
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Das D, Koirala N, Li X, Khan N, Dong F, Zhang W, Mulay P, Shrikhande G, Puskas J, Drazba J, McLennan G. Screening of Polymer-Based Drug Delivery Vehicles Targeting Folate Receptors in Triple-Negative Breast Cancer. J Vasc Interv Radiol. 2020 11; 31(11):1866-1873.e2.
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Stabler SP. Alterations in Sulfur Amino Acids as Biomarkers of Disease. J Nutr. 2020 10 01; 150(Suppl 1):2532S-2537S.
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Lachenauer ER, Stabler SP, Field MS, Stover PJ. p53 Disruption Increases Uracil Accumulation in DNA of Murine Embryonic Fibroblasts and Leads to Folic Acid-Nonresponsive Neural Tube Defects in Mice. J Nutr. 2020 07 01; 150(7):1705-1712.
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Mehrpour O, Modi M, Mansouri B, Azadi NA, Nakhaee S, Amirabadi A, Anaei-Sarab G, Shirazi FM, Weiss ST. Comparison of Vitamin B12, Vitamin D, and Folic Acid Blood Levels in Plumbism Patients and Controls in Eastern Iran. Biol Trace Elem Res. 2021 Jan; 199(1):9-17.
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Li H, Wang X, Zhao H, Wang F, Bao Y, Guo J, Chang S, Wu L, Cheng H, Chen S, Zou J, Cui X, Niswander L, Finnell RH, Wang H, Zhang T. Low folate concentration impacts mismatch repair deficiency in neural tube defects. Epigenomics. 2020 01; 12(1):5-18.
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Passarelli MN, Barry EL, Rees JR, Mott LA, Zhang D, Ahnen DJ, Bresalier RS, Haile RW, McKeown-Eyssen G, Snover DC, Cole BF, Baron JA. Folic acid supplementation and risk of colorectal neoplasia during long-term follow-up of a randomized clinical trial. Am J Clin Nutr. 2019 10 01; 110(4):903-911.
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Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, Breton CV, Allard C, Just AC, Bakulski KM, Holloway JW, Everson TM, Xu CJ, Huang RC, van der Plaat DA, Wielscher M, Merid SK, Ullemar V, Rezwan FI, Lahti J, van Dongen J, Langie SAS, Richardson TG, Magnus MC, Nohr EA, Xu Z, Duijts L, Zhao S, Zhang W, Plusquin M, DeMeo DL, Solomon O, Heimovaara JH, Jima DD, Gao L, Bustamante M, Perron P, Wright RO, Hertz-Picciotto I, Zhang H, Karagas MR, Gehring U, Marsit CJ, Beilin LJ, Vonk JM, Jarvelin MR, Bergström A, Örtqvist AK, Ewart S, Villa PM, Moore SE, Willemsen G, Standaert ARL, Håberg SE, Sørensen TIA, Taylor JA, Räikkönen K, Yang IV, Kechris K, Nawrot TS, Silver MJ, Gong YY, Richiardi L, Kogevinas M, Litonjua AA, Eskenazi B, Huen K, Mbarek H, Maguire RL, Dwyer T, Vrijheid M, Bouchard L, Baccarelli AA, Croen LA, Karmaus W, Anderson D, de Vries M, Sebert S, Kere J, Karlsson R, Arshad SH, Hämäläinen E, Routledge MN, Boomsma DI, Feinberg AP, Newschaffer CJ, Govarts E, Moisse M, Fallin MD, Melén E, Prentice AM, Kajantie E, Almqvist C, Oken E, Dabelea D, Boezen HM, Melton PE, Wright RJ, Koppelman GH, Trevisi L, Hivert MF, Sunyer J, Munthe-Kaas MC, Murphy SK, Corpeleijn E, Wiemels J, Holland N, Herceg Z, Binder EB, Davey Smith G, Jaddoe VWV, Lie RT, Nystad W, London SJ, Lawlor DA, Relton CL, Snieder H, Felix JF. Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight. Nat Commun. 2019 04 23; 10(1):1893.
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