 Folic Acid
"Folic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
| Descriptor ID |
D005492
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| MeSH Number(s) |
D03.633.100.733.631.400
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| Concept/Terms |
Folic Acid- Folic Acid
- Vitamin M
- Vitamin B9
- B9, Vitamin
- Pteroylglutamic Acid
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Below are MeSH descriptors whose meaning is more general than "Folic Acid".
Below are MeSH descriptors whose meaning is more specific than "Folic Acid".
This graph shows the total number of publications written about "Folic Acid" by people in this website by year, and whether "Folic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 1 | 2 | | 1993 | 0 | 2 | 2 | | 1994 | 0 | 1 | 1 | | 1995 | 3 | 2 | 5 | | 1996 | 1 | 2 | 3 | | 1997 | 2 | 0 | 2 | | 1998 | 0 | 2 | 2 | | 2000 | 1 | 1 | 2 | | 2001 | 4 | 1 | 5 | | 2002 | 2 | 5 | 7 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 2 | 3 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 2 | 2 | | 2008 | 5 | 1 | 6 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 4 | 4 | | 2011 | 6 | 3 | 9 | | 2012 | 3 | 3 | 6 | | 2013 | 1 | 3 | 4 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 2 | 3 | | 2016 | 3 | 2 | 5 | | 2017 | 4 | 4 | 8 | | 2018 | 2 | 5 | 7 | | 2019 | 2 | 3 | 5 | | 2020 | 4 | 0 | 4 | | 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Folic Acid" by people in Profiles.
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Hoffman MC, Freedman R, Law AJ, Clark AM, Hunter SK. Maternal nutrients and effects of gestational COVID-19 infection on fetal brain development. Clin Nutr ESPEN. 2021 06; 43:1-8.
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Maclean KN, Jiang H, Phinney WN, Mclagan BM, Roede JR, Stabler SP. Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis. Mol Genet Metab. 2021 02; 132(2):128-138.
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Maruvada P, Stover PJ, Mason JB, Bailey RL, Davis CD, Field MS, Finnell RH, Garza C, Green R, Gueant JL, Jacques PF, Klurfeld DM, Lamers Y, MacFarlane AJ, Miller JW, Molloy AM, O'Connor DL, Pfeiffer CM, Potischman NA, Rodricks JV, Rosenberg IH, Ross SA, Shane B, Selhub J, Stabler SP, Trasler J, Yamini S, Zappalà G. Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop. Am J Clin Nutr. 2020 11 11; 112(5):1390-1403.
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Das D, Koirala N, Li X, Khan N, Dong F, Zhang W, Mulay P, Shrikhande G, Puskas J, Drazba J, McLennan G. Screening of Polymer-Based Drug Delivery Vehicles Targeting Folate Receptors in Triple-Negative Breast Cancer. J Vasc Interv Radiol. 2020 11; 31(11):1866-1873.e2.
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Stabler SP. Alterations in Sulfur Amino Acids as Biomarkers of Disease. J Nutr. 2020 10 01; 150(Suppl 1):2532S-2537S.
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Lachenauer ER, Stabler SP, Field MS, Stover PJ. p53 Disruption Increases Uracil Accumulation in DNA of Murine Embryonic Fibroblasts and Leads to Folic Acid-Nonresponsive Neural Tube Defects in Mice. J Nutr. 2020 07 01; 150(7):1705-1712.
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Mehrpour O, Modi M, Mansouri B, Azadi NA, Nakhaee S, Amirabadi A, Anaei-Sarab G, Shirazi FM, Weiss ST. Comparison of Vitamin B12, Vitamin D, and Folic Acid Blood Levels in Plumbism Patients and Controls in Eastern Iran. Biol Trace Elem Res. 2021 Jan; 199(1):9-17.
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Li H, Wang X, Zhao H, Wang F, Bao Y, Guo J, Chang S, Wu L, Cheng H, Chen S, Zou J, Cui X, Niswander L, Finnell RH, Wang H, Zhang T. Low folate concentration impacts mismatch repair deficiency in neural tube defects. Epigenomics. 2020 01; 12(1):5-18.
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Jessel RH, Rosario FJ, Chen YY, Erickson K, Teal SB, Kramer A, Cotton E, Ryan S, Jansson T, Powell TL. Decreased placental folate transporter expression and activity in first and second trimester in obese mothers. J Nutr Biochem. 2020 03; 77:108305.
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Passarelli MN, Barry EL, Rees JR, Mott LA, Zhang D, Ahnen DJ, Bresalier RS, Haile RW, McKeown-Eyssen G, Snover DC, Cole BF, Baron JA. Folic acid supplementation and risk of colorectal neoplasia during long-term follow-up of a randomized clinical trial. Am J Clin Nutr. 2019 10 01; 110(4):903-911.
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