 Synapses
"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
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| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 2 | 2 | 4 | | 1992 | 2 | 2 | 4 | | 1993 | 1 | 1 | 2 | | 1994 | 1 | 1 | 2 | | 1995 | 1 | 4 | 5 | | 1996 | 1 | 2 | 3 | | 1997 | 0 | 1 | 1 | | 1998 | 2 | 1 | 3 | | 1999 | 1 | 1 | 2 | | 2000 | 3 | 1 | 4 | | 2001 | 2 | 2 | 4 | | 2002 | 2 | 2 | 4 | | 2003 | 4 | 5 | 9 | | 2004 | 5 | 3 | 8 | | 2005 | 4 | 0 | 4 | | 2006 | 12 | 4 | 16 | | 2007 | 7 | 4 | 11 | | 2008 | 6 | 4 | 10 | | 2009 | 6 | 3 | 9 | | 2010 | 12 | 3 | 15 | | 2011 | 10 | 6 | 16 | | 2012 | 7 | 2 | 9 | | 2013 | 3 | 4 | 7 | | 2014 | 7 | 7 | 14 | | 2015 | 3 | 11 | 14 | | 2016 | 7 | 6 | 13 | | 2017 | 4 | 5 | 9 | | 2018 | 11 | 3 | 14 | | 2019 | 9 | 5 | 14 | | 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Tullis JE, Rumian NL, Brown CN, Bayer KU. The CaMKII K42M and K42R mutations are equivalent in suppressing kinase activity and targeting. PLoS One. 2020; 15(7):e0236478.
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Tesic V, Joksimovic SM, Quillinan N, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V. Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABAA currents, but are not neurotoxic to the developing rat brain. Br J Anaesth. 2020 05; 124(5):603-613.
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Poleg-Polsky A. Dendritic Spikes Expand the Range of Well Tolerated Population Noise Structures. J Neurosci. 2019 11 13; 39(46):9173-9184.
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Hughes AN, Appel B. Oligodendrocytes express synaptic proteins that modulate myelin sheath formation. Nat Commun. 2019 09 11; 10(1):4125.
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Gire DH, Zak JD, Bourne JN, Goodson NB, Schoppa NE. Balancing Extrasynaptic Excitation and Synaptic Inhibition within Olfactory Bulb Glomeruli. eNeuro. 2019 Jul/Aug; 6(4).
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Mamaligas AA, Barcomb K, Ford CP. Cholinergic Transmission at Muscarinic Synapses in the Striatum Is Driven Equally by Cortical and Thalamic Inputs. Cell Rep. 2019 07 23; 28(4):1003-1014.e3.
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Kennedy MJ, Hanus C. Architecture and Dynamics of the Neuronal Secretory Network. Annu Rev Cell Dev Biol. 2019 10 06; 35:543-566.
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Dittmer PJ, Dell'Acqua ML, Sather WA. Synaptic crosstalk conferred by a zone of differentially regulated Ca2+ signaling in the dendritic shaft adjoining a potentiated spine. Proc Natl Acad Sci U S A. 2019 07 02; 116(27):13611-13620.
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Jones KA, Sumiya M, Woolfrey KM, Srivastava DP, Penzes P. Loss of EPAC2 alters dendritic spine morphology and inhibitory synapse density. Mol Cell Neurosci. 2019 07; 98:19-31.
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Martinello K, Giacalone E, Migliore M, Brown DA, Shah MM. The subthreshold-active KV7 current regulates neurotransmission by limiting spike-induced Ca2+ influx in hippocampal mossy fiber synaptic terminals. Commun Biol. 2019; 2:145.
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