Synapses
"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Descriptor ID |
D013569
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MeSH Number(s) |
A08.850 A11.284.149.165.420.780
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
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1992 | 1 | 2 | 3 | 1993 | 1 | 0 | 1 | 1994 | 1 | 1 | 2 | 1995 | 1 | 2 | 3 | 1996 | 1 | 2 | 3 | 1998 | 2 | 0 | 2 | 1999 | 1 | 1 | 2 | 2000 | 3 | 1 | 4 | 2001 | 1 | 2 | 3 | 2002 | 2 | 2 | 4 | 2003 | 4 | 3 | 7 | 2004 | 5 | 2 | 7 | 2005 | 3 | 0 | 3 | 2006 | 9 | 4 | 13 | 2007 | 3 | 4 | 7 | 2008 | 4 | 3 | 7 | 2009 | 4 | 2 | 6 | 2010 | 6 | 2 | 8 | 2011 | 6 | 5 | 11 | 2012 | 5 | 2 | 7 | 2013 | 1 | 2 | 3 | 2014 | 4 | 5 | 9 | 2015 | 2 | 6 | 8 | 2016 | 6 | 6 | 12 | 2017 | 4 | 4 | 8 | 2018 | 9 | 2 | 11 | 2019 | 5 | 4 | 9 | 2020 | 0 | 2 | 2 | 2021 | 2 | 6 | 8 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Basta T, Morgan GP, O'Toole ET, Rao NR, Savas JN, Stowell MHB. Electron Tomographic Methods for Studying Organelles of the Murine Chemical Synapse. Methods Mol Biol. 2022; 2473:129-139.
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Garcia JD, Gookin SE, Crosby KC, Schwartz SL, Tiemeier E, Kennedy MJ, Dell'Acqua ML, Herson PS, Quillinan N, Smith KR. Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity. Cell Rep. 2021 12 21; 37(12):110142.
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Actor-Engel HS, Schwartz SL, Crosby KC, Sinnen BL, Prikhodko O, Ramsay HJ, Bourne JN, Winborn CS, Lucas A, Smith KR, Dell'Acqua ML, Kennedy MJ. Precision Mapping of Amyloid-ß Binding Reveals Perisynaptic Localization and Spatially Restricted Plasticity Deficits. eNeuro. 2021 Nov-Dec; 8(6).
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Wilson CE, Lasher RS, Yang R, Dzowo Y, Kinnamon JC, Finger TE. Taste Bud Connectome: Implications for Taste Information Processing. J Neurosci. 2022 02 02; 42(5):804-816.
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Judd EN, Lewis SM, Person AL. Diverse inhibitory projections from the cerebellar interposed nucleus. Elife. 2021 09 20; 10.
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Kadgien CA, Kamesh A, Milnerwood AJ. Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition. Mol Brain. 2021 09 16; 14(1):143.
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Bourke AM, Schwartz SL, Bowen AB, Kleinjan MS, Winborn CS, Kareemo DJ, Gutnick A, Schwarz TL, Kennedy MJ. zapERtrap: A light-regulated ER release system reveals unexpected neuronal trafficking pathways. J Cell Biol. 2021 09 06; 220(9).
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Svalina MN, Guthman EM, Cea-Del Rio CA, Kushner JK, Baca SM, Restrepo D, Huntsman MM. Hyperexcitability and Loss of Feedforward Inhibition Contribute to Aberrant Plasticity in the Fmr1KO Amygdala. eNeuro. 2021 May-Jun; 8(3).
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Cai Y, Nielsen BE, Boxer EE, Aoto J, Ford CP. Loss of nigral excitation of cholinergic interneurons contributes to parkinsonian motor impairments. Neuron. 2021 04 07; 109(7):1137-1149.e5.
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Tullis JE, Rumian NL, Brown CN, Bayer KU. The CaMKII K42M and K42R mutations are equivalent in suppressing kinase activity and targeting. PLoS One. 2020; 15(7):e0236478.
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