 Synapses
"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
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| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 2 | 2 | 4 | | 1992 | 2 | 2 | 4 | | 1993 | 1 | 1 | 2 | | 1994 | 1 | 1 | 2 | | 1995 | 1 | 4 | 5 | | 1996 | 1 | 2 | 3 | | 1998 | 2 | 1 | 3 | | 1999 | 1 | 1 | 2 | | 2000 | 3 | 1 | 4 | | 2001 | 2 | 2 | 4 | | 2002 | 2 | 2 | 4 | | 2003 | 4 | 5 | 9 | | 2004 | 5 | 2 | 7 | | 2005 | 4 | 0 | 4 | | 2006 | 12 | 4 | 16 | | 2007 | 7 | 4 | 11 | | 2008 | 6 | 3 | 9 | | 2009 | 6 | 3 | 9 | | 2010 | 11 | 3 | 14 | | 2011 | 8 | 6 | 14 | | 2012 | 7 | 2 | 9 | | 2013 | 2 | 4 | 6 | | 2014 | 6 | 8 | 14 | | 2015 | 3 | 11 | 14 | | 2016 | 8 | 6 | 14 | | 2017 | 5 | 5 | 10 | | 2018 | 11 | 4 | 15 | | 2019 | 10 | 5 | 15 | | 2020 | 0 | 3 | 3 | | 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Svalina MN, Guthman EM, Cea-Del Rio CA, Kushner JK, Baca SM, Restrepo D, Huntsman MM. Hyperexcitability and Loss of Feedforward Inhibition Contribute to Aberrant Plasticity in the Fmr1KO Amygdala. eNeuro. 2021 May-Jun; 8(3).
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Cai Y, Nielsen BE, Boxer EE, Aoto J, Ford CP. Loss of nigral excitation of cholinergic interneurons contributes to parkinsonian motor impairments. Neuron. 2021 04 07; 109(7):1137-1149.e5.
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Tullis JE, Rumian NL, Brown CN, Bayer KU. The CaMKII K42M and K42R mutations are equivalent in suppressing kinase activity and targeting. PLoS One. 2020; 15(7):e0236478.
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Rajgor D, Purkey AM, Sanderson JL, Welle TM, Garcia JD, Dell'Acqua ML, Smith KR. Local miRNA-Dependent Translational Control of GABAAR Synthesis during Inhibitory Long-Term Potentiation. Cell Rep. 2020 06 23; 31(12):107785.
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Tesic V, Joksimovic SM, Quillinan N, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V. Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABAA currents, but are not neurotoxic to the developing rat brain. Br J Anaesth. 2020 05; 124(5):603-613.
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Poleg-Polsky A. Dendritic Spikes Expand the Range of Well Tolerated Population Noise Structures. J Neurosci. 2019 11 13; 39(46):9173-9184.
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Hughes AN, Appel B. Oligodendrocytes express synaptic proteins that modulate myelin sheath formation. Nat Commun. 2019 09 11; 10(1):4125.
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Gire DH, Zak JD, Bourne JN, Goodson NB, Schoppa NE. Balancing Extrasynaptic Excitation and Synaptic Inhibition within Olfactory Bulb Glomeruli. eNeuro. 2019 Jul/Aug; 6(4).
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Mamaligas AA, Barcomb K, Ford CP. Cholinergic Transmission at Muscarinic Synapses in the Striatum Is Driven Equally by Cortical and Thalamic Inputs. Cell Rep. 2019 07 23; 28(4):1003-1014.e3.
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Kennedy MJ, Hanus C. Architecture and Dynamics of the Neuronal Secretory Network. Annu Rev Cell Dev Biol. 2019 10 06; 35:543-566.
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