 Receptors, CXCR4
"Receptors, CXCR4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
CXCR receptors with specificity for CXCL12 CHEMOKINE. The receptors may play a role in HEMATOPOIESIS regulation and can also function as coreceptors for the HUMAN IMMUNODEFICIENCY VIRUS.
| Descriptor ID |
D019718
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| MeSH Number(s) |
D12.776.543.750.695.160.500.400 D12.776.543.750.705.852.125.500.400 D12.776.543.750.830.700.650
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| Concept/Terms |
Receptors, CXCR4- Receptors, CXCR4
- LESTR Receptor
- CXC Chemokine Receptor 4
- Fusin
- CXCR4 Receptor
- Receptor, CXCR4
- CXCR4 Receptors
- Leukocyte-Derived Seven-Transmembrane Domain Receptor
- Leukocyte Derived Seven Transmembrane Domain Receptor
- Receptor, LESTR
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Below are MeSH descriptors whose meaning is more general than "Receptors, CXCR4".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Chemokine [D12.776.543.750.695.160]
- Receptors, CXCR [D12.776.543.750.695.160.500]
- Receptors, CXCR4 [D12.776.543.750.695.160.500.400]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Chemokine [D12.776.543.750.705.852.125]
- Receptors, CXCR [D12.776.543.750.705.852.125.500]
- Receptors, CXCR4 [D12.776.543.750.705.852.125.500.400]
- Receptors, Virus [D12.776.543.750.830]
- Receptors, HIV [D12.776.543.750.830.700]
- Receptors, CXCR4 [D12.776.543.750.830.700.650]
Below are MeSH descriptors whose meaning is more specific than "Receptors, CXCR4".
This graph shows the total number of publications written about "Receptors, CXCR4" by people in this website by year, and whether "Receptors, CXCR4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 3 | 1 | 4 | | 2007 | 1 | 4 | 5 | | 2008 | 0 | 1 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 2 | 1 | 3 | | 2011 | 1 | 1 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 2 | 3 | | 2014 | 3 | 1 | 4 | | 2015 | 1 | 1 | 2 | | 2017 | 2 | 4 | 6 | | 2018 | 1 | 2 | 3 | | 2019 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, CXCR4" by people in Profiles.
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Almodovar S, Wade BE, Porter KM, Smith JM, Lopez-Astacio RA, Bijli K, Kang BY, Cribbs SK, Guidot DM, Molehin D, McNair BK, Pumarejo-Gomez L, Perez Hernandez J, Salazar EA, Martinez EG, Huang L, Kessing CF, Suarez-Martinez EB, Pruitt K, Hsue PY, Tyor WR, Flores SC, Sutliff RL. HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension. Sci Rep. 2020 07 16; 10(1):11696.
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Castillo JJ, Moreno DF, Arbelaez MI, Hunter ZR, Treon SP. CXCR4 mutations affect presentation and outcomes in patients with Waldenström macroglobulinemia: A systematic review. Expert Rev Hematol. 2019 10; 12(10):873-881.
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LaRocca TJ, Altman P, Jarrah AA, Gordon R, Wang E, Hadri L, Burke MW, Haddad GE, Hajjar RJ, Tarzami ST. CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy. Int J Mol Sci. 2019 May 08; 20(9).
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Dinkel BA, Kremer KN, Rollins MR, Medlyn MJ, Hedin KE. GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3K?/PREX1 signaling and T cell cytokine secretion. J Biol Chem. 2018 09 07; 293(36):14022-14039.
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Sterner RM, Kremer KN, Dudakovic A, Westendorf JJ, van Wijnen AJ, Hedin KE. Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis. J Immunol. 2018 08 01; 201(3):1086-1096.
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Barwinska D, Oueini H, Poirier C, Albrecht ME, Bogatcheva NV, Justice MJ, Saliba J, Schweitzer KS, Broxmeyer HE, March KL, Petrache I. AMD3100 ameliorates cigarette smoke-induced emphysema-like manifestations in mice. . 2018 09 01; 315(3):L382-L386.
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Jarrah AA, Schwarskopf M, Wang ER, LaRocca T, Dhume A, Zhang S, Hadri L, Hajjar RJ, Schecter AD, Tarzami ST. SDF-1 induces TNF-mediated apoptosis in cardiac myocytes. Apoptosis. 2018 01; 23(1):79-91.
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Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF. Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. Elife. 2017 11 09; 6.
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Dwyer-Nield L, Hickey GA, Friedman M, Choo K, McArthur DG, Tennis MA, New ML, Geraci M, Keith RL. The Second-Generation PGI2 Analogue Treprostinil Fails to Chemoprevent Tumors in a Murine Lung Adenocarcinoma Model. Cancer Prev Res (Phila). 2017 Nov; 10(11):671-679.
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Kremer KN, Dinkel BA, Sterner RM, Osborne DG, Jevremovic D, Hedin KE. TCR-CXCR4 signaling stabilizes cytokine mRNA transcripts via a PREX1-Rac1 pathway: implications for CTCL. Blood. 2017 08 24; 130(8):982-994.
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