Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals.

Kumar S, Raina K, Agarwal C, Agarwal R. Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals. Oncotarget. 2014 Jul 15; 5(13):4972-89.

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subject areas

Antioxidants
Cell Line, Tumor
Cell Proliferation
Cell Survival
Colonic Neoplasms
Dose-Response Relationship, Drug
Gene Expression Regulation, Neoplastic
HT29 Cells
Humans
Interleukin-4
Interleukin-6
Kinetics
Microscopy, Confocal
Neoplastic Stem Cells
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Silymarin
Spheroids, Cellular
Transcription Factors

authors with profiles

Sushil Kumar
Chapla Agarwal
Rajesh Agarwal